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N-Acetyl-S-farnesyl-L-cysteine (AFC) - ≥98%, high purity , CAS No.135304-07-3

  • ≥98%
Item Number
A275559
Grouped product items
SKUSizeAvailabilityPrice Qty
A275559-5mg
5mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$85.90
A275559-25mg
25mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$361.90

Specific S-farnesylcysteine methyl transferase inhibitor

Basic Description

Synonyms135304-07-3|Ac-Cys(farnesyl)-OH|Arazine|N-Acetyl-S-trans,trans-farnesyl-L-cysteine|N-acetyl-S-farnesylcysteine|acetyl-farnesyl-cysteine|Acetyl farnesylcysteine|N-ACETYL-S-FARNESYL-L-CYSTEINE|CHEMBL1555989|N-acetyl-L-farnesylcysteine|KK6984C8O3|(2R)-2-acet
Specifications & Purity≥98%
Biochemical and Physiological MechanismsSpecific S-farnesylcysteine methyl transferase inhibitor (K m = 20 µM). Modulator of G protein and G protein coupled receptor signaling. Inhibits neutrophil chemotaxis and other inflammatory responses in vitro .
Storage TempStore at -20°C,Desiccated
Shipped InIce chest + Ice pads
NoteWherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour. Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
Product Description

Store at -20°C. Store under desiccating conditions. The product can be stored for up to 12 months.

Associated Targets

VDR Tclin Vitamin D3 receptor 0 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

ICMT Tchem Protein-S-isoprenylcysteine O-methyltransferase 0 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

EPHX2 Tchem Bifunctional epoxide hydrolase 2 0 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

HDAC6 Tclin Histone deacetylase 6 0 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

KAT2A Tchem Histone acetyltransferase KAT2A 0 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

MAPT Tclin Microtubule-associated protein tau 0 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

Names and Identifiers

IUPAC Name (2R)-2-acetamido-3-[(2E,6E)-3,7,11-trimethyldodeca-2,6,10-trienyl]sulfanylpropanoic acid
INCHI InChI=1S/C20H33NO3S/c1-15(2)8-6-9-16(3)10-7-11-17(4)12-13-25-14-19(20(23)24)21-18(5)22/h8,10,12,19H,6-7,9,11,13-14H2,1-5H3,(H,21,22)(H,23,24)/b16-10+,17-12+/t19-/m0/s1
InChi Key XTURYZYJYQRJDO-BNAHBJSTSA-N
Canonical SMILES CC(=CCCC(=CCCC(=CCSCC(C(=O)O)NC(=O)C)C)C)C
Isomeric SMILES CC(=CCC/C(=C/CC/C(=C/CSC[C@@H](C(=O)O)NC(=O)C)/C)/C)C
PubChem CID 6438381
Molecular Weight 367.55

Certificates

Certificate of Analysis(COA)

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Chemical and Physical Properties

SolubilitySoluble in water to 50 mM (with warming), in DMSO to 50 mM and in ethanol to 50 mM

Related Documents

Solution Calculators