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Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) |
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SKU | Size | Availability | Price | Qty |
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N131765-5g | 5g | In stock | $109.90 | |
N131765-25g | 25g | In stock | $330.90 | |
N131765-100g | 100g | In stock | $1,190.90 |
Discover N-Benzyl-p-Toluenesulfonamide by Aladdin Scientific in ≥98.0%(HPLC) for only $109.90. Available - in Ligands at Aladdin Scientific. Selective inhibitor of Ca2+-stimulated myosin S1 ATPase Tags: Non heterocyclic block, Sulfur containing compounds.
Synonyms | N-Benzyl-p-toluenesulfonamide|1576-37-0|N-Tosylbenzylamine|N-Benzyl-4-methylbenzenesulfonamide|N-Benzyl-4-methyl-benzenesulfonamide|N-Benzyl-p-toluenesulphonamide|p-Toluenesulfonamide, N-benzyl-|Benzenesulfonamide, 4-methyl-N-(phenylmethyl)-|N-benzyl-4-me |
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Specifications & Purity | ≥98.0%(HPLC) |
Storage Temp | Protected from light,Store at -20°C,Argon charged |
Shipped In | Dry ice |
Product Description | product description: An aryl sulphonamide that acts as a potent inhibitor of Ca2+-stimulated myosin S1 actin-stimulated ATPase activity (IC50 = ~5 µM). Also blocks actin-stimulated ATPase activity with similar potency (IC50 = 5 µM). Reversibly blocks gliding motility of skeletal muscle myosin (IC50<2 µM). Less effective in suppressing contraction in rat myocardial and rabbit slow twitch muscle compared to skeletal muscle. Does not inhibit platelet myosin II. A potent inhibitor of Ca2+-stimulated myosin S1 ATPase (IC50 = ~ 5 µM) and reversibly blocks the gliding motility. It also weakens myosin’s interaction with F-actin. Much less effective in suppressing contraction in rat myocardial or rabbit slow twitch muscle and has no effect on platelet myosin II. |
Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) |
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Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) |
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IUPAC Name | N-benzyl-4-methylbenzenesulfonamide |
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INCHI | InChI=1S/C14H15NO2S/c1-12-7-9-14(10-8-12)18(16,17)15-11-13-5-3-2-4-6-13/h2-10,15H,11H2,1H3 |
InChi Key | WTHKAJZQYNKTCJ-UHFFFAOYSA-N |
Canonical SMILES | CC1=CC=C(C=C1)S(=O)(=O)NCC2=CC=CC=C2 |
Isomeric SMILES | CC1=CC=C(C=C1)S(=O)(=O)NCC2=CC=CC=C2 |
RTECS | XT5490000 |
PubChem CID | 95801 |
Molecular Weight | 261.34 |
Beilstein | 12(3)2328 |
Reaxy-Rn | 2217277 |
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Lot Number | Certificate Type | Date | Item |
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L2121042 | Certificate of Analysis | Oct 23, 2023 | N131765 |
D2315257 | Certificate of Analysis | Apr 23, 2023 | N131765 |
D2315258 | Certificate of Analysis | Apr 23, 2023 | N131765 |
D2315287 | Certificate of Analysis | Apr 23, 2023 | N131765 |
D2315293 | Certificate of Analysis | Apr 23, 2023 | N131765 |
D2315863 | Certificate of Analysis | Apr 23, 2023 | N131765 |
D2315872 | Certificate of Analysis | Apr 23, 2023 | N131765 |
E2011034 | Certificate of Analysis | Apr 13, 2022 | N131765 |
Solubility | Chloroform (Slightly), Dichloromethane, Ethyl Acetate (Slightly) |
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Sensitivity | light sensitive |
Melt Point(°C) | 115 °C |
Pictogram(s) | GHS06 |
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Signal | Danger |
Hazard Statements | H301:Toxic if swallowed |
Precautionary Statements | P321:Specific treatment (see ... on this label). P405:Store locked up. P501:Dispose of contents/container to ... P264:Wash hands [and …] thoroughly after handling. P270:Do not eat, drink or smoke when using this product. P330:Rinse mouth. P301+P316:IF SWALLOWED: Get emergency medical help immediately. |
RTECS | XT5490000 |
Reaxy-Rn | 2217277 |