N-Cyclohexyl-N-[2-(3,5-dimethyl-pyrazol-1-yl)-6-methyl-4-pyrimidinamine - ≥98% (HPLC), high purity , CAS No.73029-73-9, Activator of K Ca2.2;Activator of K Ca2.3

Item Number

N136726

• Synonyms: CyPPA|73029-73-9|N-cyclohexyl-2-(3,5-dimethyl-1H-pyrazol-1-yl)-6-methylpyrimidin-4-amine|cyclohexyl-[2-(3,5-dimethyl-pyrazol-1-yl)-6-methyl-pyrimidin-4-yl]-amine|CHEMBL453730|N-cyclohexyl-2-(3,5-dimethylpyrazol-1-yl)-6-methylpyrimidin-4-amine|N-Cyclohexyl
• Specifications & Purity: Moligand™, ≥98%(HPLC)
• Biochemical and Physiological Mechanisms: First selective small conductance Ca 2+ -activated K + channel (SK) activator. Selectively opens SK2 and SK3 channels (EC 50 values are 5.6 and 14 μM, respectively). Shows no activity at SK1 and IK. Additionally reduces activity and excitability of dopami
• Storage Temp: Store at -20°C
• Shipped In: Ice chest + Ice pads
• Grade: Moligand™
• Action Type: ACTIVATOR
• Mechanism of action: Activator of K Ca2.2;Activator of K Ca2.3
• Note: Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour. Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.