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N-Desmethyl Galanthamine - ≥95%, high purity , CAS No.41303-74-6

  • ≥95%
Item Number
N334810
Grouped product items
SKUSizeAvailabilityPrice Qty
N334810-1mg
1mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$89.90
N334810-2.5mg
2.5mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$199.90
N334810-5mg
5mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$359.90

a metabolite of galanthamine

View related series
Cholinesterase (ChE)

Basic Description

SynonymsNorgalanthamine|N-Desmethyl Galanthamine|41303-74-6|N-Desmethylgalantamine|Norgalantamine|N-Norgalanthamine|N-Demethylgalanthamine|N-Desmethylgalanthamine|UNII-2BPQ4IVQ21|2BPQ4IVQ21|CHEMBL1385|CHEBI:31919|(1S,12S,14R)-9-methoxy-11-oxa-4-azatetracyclo[8.6.
Specifications & Purity≥95%
Biochemical and Physiological MechanismsN-Desmethyl Galanthamine is a metabolite of Galanthamine. Galanthamine is a potent acetylcholinesterase (AChE) inhibitor with an IC50 of 500 nM.
Storage TempProtected from light,Store at -20°C
Shipped InIce chest + Ice pads
Product Description

N-Desmethyl Galanthamine is a metabolite of Galanthamine, a selective acetylcholinesterase inhibitor.

Associated Targets

ACHE Tclin Acetylcholinesterase 0 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

Names and Identifiers

IUPAC Name (1S,12S,14R)-9-methoxy-11-oxa-4-azatetracyclo[8.6.1.01,12.06,17]heptadeca-6(17),7,9,15-tetraen-14-ol
INCHI InChI=1S/C16H19NO3/c1-19-12-3-2-10-9-17-7-6-16-5-4-11(18)8-13(16)20-15(12)14(10)16/h2-5,11,13,17-18H,6-9H2,1H3/t11-,13-,16-/m0/s1
InChi Key AIXQQSTVOSFSMO-RBOXIYTFSA-N
Canonical SMILES COC1=C2C3=C(CNCCC34C=CC(CC4O2)O)C=C1
Isomeric SMILES COC1=C2C3=C(CNCC[C@]34C=C[C@@H](C[C@@H]4O2)O)C=C1
PubChem CID 9838394
Molecular Weight 273.33

Certificates

Certificate of Analysis(COA)

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Chemical and Physical Properties

SolubilitySouluble in dichloromethane, ethyl acetate and methanol.
SensitivityLight sensitive
Melt Point(°C)>135°C (lit.)(dec.)

Safety and Hazards(GHS)

Pictogram(s) GHS06,   GHS07
Signal Danger
Hazard Statements

H315:Causes skin irritation

H301:Toxic if swallowed

H331:Toxic if inhaled

H317:May cause an allergic skin reaction

Precautionary Statements

P261:Avoid breathing dust/fume/gas/mist/vapors/spray.

P280:Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352:IF ON SKIN: wash with plenty of water.

P321:Specific treatment (see ... on this label).

P405:Store locked up.

P501:Dispose of contents/container to ...

P264:Wash hands [and …] thoroughly after handling.

P271:Use only outdoors or in a well-ventilated area.

P270:Do not eat, drink or smoke when using this product.

P304+P340:IF INHALED: Remove person to fresh air and keep comfortable for breathing.

P403+P233:Store in a well-ventilated place. Keep container tightly closed.

P272:Contaminated work clothing should not be allowed out of the workplace.

P333+P313:IF SKIN irritation or rash occurs: Get medical advice/attention.

P362+P364:Take off contaminated clothing and wash it before reuse.

P330:Rinse mouth.

P301+P316:IF SWALLOWED: Get emergency medical help immediately.

P332+P317:If skin irritation occurs: Get medical help.

P316:Get emergency medical help immediately.

Related Documents

Solution Calculators