Determine the necessary mass, volume, or concentration for preparing a solution.
Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) |
---|
SKU | Size | Availability | Price | Qty |
---|---|---|---|---|
N334810-1mg | 1mg | Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding. | $89.90 | |
N334810-2.5mg | 2.5mg | Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding. | $199.90 | |
N334810-5mg | 5mg | Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding. | $359.90 |
a metabolite of galanthamine
Synonyms | Norgalanthamine|N-Desmethyl Galanthamine|41303-74-6|N-Desmethylgalantamine|Norgalantamine|N-Norgalanthamine|N-Demethylgalanthamine|N-Desmethylgalanthamine|UNII-2BPQ4IVQ21|2BPQ4IVQ21|CHEMBL1385|CHEBI:31919|(1S,12S,14R)-9-methoxy-11-oxa-4-azatetracyclo[8.6. |
---|---|
Specifications & Purity | ≥95% |
Biochemical and Physiological Mechanisms | N-Desmethyl Galanthamine is a metabolite of Galanthamine. Galanthamine is a potent acetylcholinesterase (AChE) inhibitor with an IC50 of 500 nM. |
Storage Temp | Protected from light,Store at -20°C |
Shipped In | Ice chest + Ice pads |
Product Description | N-Desmethyl Galanthamine is a metabolite of Galanthamine, a selective acetylcholinesterase inhibitor. |
Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) |
---|
IUPAC Name | (1S,12S,14R)-9-methoxy-11-oxa-4-azatetracyclo[8.6.1.01,12.06,17]heptadeca-6(17),7,9,15-tetraen-14-ol |
---|---|
INCHI | InChI=1S/C16H19NO3/c1-19-12-3-2-10-9-17-7-6-16-5-4-11(18)8-13(16)20-15(12)14(10)16/h2-5,11,13,17-18H,6-9H2,1H3/t11-,13-,16-/m0/s1 |
InChi Key | AIXQQSTVOSFSMO-RBOXIYTFSA-N |
Canonical SMILES | COC1=C2C3=C(CNCCC34C=CC(CC4O2)O)C=C1 |
Isomeric SMILES | COC1=C2C3=C(CNCC[C@]34C=C[C@@H](C[C@@H]4O2)O)C=C1 |
PubChem CID | 9838394 |
Molecular Weight | 273.33 |
Enter Lot Number to search for COA:
Solubility | Souluble in dichloromethane, ethyl acetate and methanol. |
---|---|
Sensitivity | Light sensitive |
Melt Point(°C) | >135°C (lit.)(dec.) |
Pictogram(s) | GHS06, GHS07 |
---|---|
Signal | Danger |
Hazard Statements | H315:Causes skin irritation H301:Toxic if swallowed H331:Toxic if inhaled H317:May cause an allergic skin reaction |
Precautionary Statements | P261:Avoid breathing dust/fume/gas/mist/vapors/spray. P280:Wear protective gloves/protective clothing/eye protection/face protection. P302+P352:IF ON SKIN: wash with plenty of water. P321:Specific treatment (see ... on this label). P405:Store locked up. P501:Dispose of contents/container to ... P264:Wash hands [and …] thoroughly after handling. P271:Use only outdoors or in a well-ventilated area. P270:Do not eat, drink or smoke when using this product. P304+P340:IF INHALED: Remove person to fresh air and keep comfortable for breathing. P403+P233:Store in a well-ventilated place. Keep container tightly closed. P272:Contaminated work clothing should not be allowed out of the workplace. P333+P313:IF SKIN irritation or rash occurs: Get medical advice/attention. P362+P364:Take off contaminated clothing and wash it before reuse. P330:Rinse mouth. P301+P316:IF SWALLOWED: Get emergency medical help immediately. P332+P317:If skin irritation occurs: Get medical help. P316:Get emergency medical help immediately. |