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Halogenated Heterocycles
N-Ethyl-N-isopropylpropan-2-aminium 4-Oxo-3-(perfluoropyridin-4-yl)-1,5-dioxaspiro[5.5]undec-2-en-2-olate - ≥95%, high purity , CAS No.1632145-10-8

N-Ethyl-N-isopropylpropan-2-aminium 4-Oxo-3-(perfluoropyridin-4-yl)-1,5-dioxaspiro[5.5]undec-2-en-2-olate - ≥95%, high purity , CAS No.1632145-10-8

Item Number

N463373

Grouped product items
SKU	Size	Availability	Price	Qty
N463373-1g	1g	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$309.90	+-

Basic Description

Specifications & Purity	≥95%
Storage Temp	Store at 2-8°C
Shipped In	Wet ice
Product Description	Description N-Ethyl-N-isopropylpropan-2-aminium 4-oxo-3-(perfluoropyridin-4-yl)-1,5-dioxaspiro[5.5]undec-2-en-2-olate is a fluoroarylated-Meldrum′s acid adduct. It can be prepared by reacting pentafluoropyridine with cyclohexyl-Meldrum′s acid in the presence ofN,N-diisopropylethylamine and acetonitrile.This compound undergoes cycloreversion to form the fluoro(hetero)aryl ketene, which undergoes efficient coupling with nucleophiles and allows rapid incorporation of highly fluorinated α-fluoro(hetero)aryl acetic acid derivatives.N-Ethyl-N-isopropylpropan-2-aminium 4-oxo-3-(perfluoropyridin-4-yl)-1,5-dioxaspiro[5.5]undec-2-en-2-olate may be used to synthesize ethyl 2-(2-(perfluoropyridin-4-yl)acetamido)-acetate andN-methoxy-N-methyl-2-(perfluoropyridin-4-yl)-acetamide.

IUPAC Name	ethyl-di(propan-2-yl)azanium;4-oxo-3-(2,3,5,6-tetrafluoropyridin-4-yl)-1,5-dioxaspiro[5.5]undec-2-en-2-olate
INCHI	InChI=1S/C14H11F4NO4.C8H19N/c15-8-6(9(16)11(18)19-10(8)17)7-12(20)22-14(23-13(7)21)4-2-1-3-5-14;1-6-9(7(2)3)8(4)5/h20H,1-5H2;7-8H,6H2,1-5H3
InChi Key	RCRKIJBXPWODMA-UHFFFAOYSA-N
Canonical SMILES	CC[NH+](C(C)C)C(C)C.C1CCC2(CC1)OC(=C(C(=O)O2)C3=C(C(=NC(=C3F)F)F)F)[O-]
PubChem CID	124203082
Molecular Weight	462.48

C of A & Other Certificates(BSE/TSE, COO):

Analytical Chart:

RIDADR	NONHforallmodesoftransport

1. Sameera M Senaweera, Jimmie D Weaver,. (2014-10-02) Selective perfluoro- and polyfluoroarylation of Meldrum's acid.. The Journal of organic chemistry, 79 ((21)): ( 10466-10476 ). [PMID:25271542]

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