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SKU | Size | Availability | Price | Qty |
---|---|---|---|---|
I287459-5mg | 5mg | 7 | $157.90 | |
I287459-25mg | 25mg | 6 | $444.90 | |
I287459-100mg | 100mg | 5 | $969.90 | |
I287459-250mg | 250mg | 4 | $2,182.90 |
Broad spectrum cysteine reactive probe
Synonyms | IA-Alkyne |
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Specifications & Purity | ≥97% |
Biochemical and Physiological Mechanisms | Broad spectrum cysteine reactive probe. Covalently binds cysteine residues in proteins. Can be utilized for covalent fragment-based ligand discovery (FBLD) and to identify Zn2+-binding cysteines. Used as a click-chemistry handle to attach a fluorophore or |
Storage Temp | Protected from light,Store at -20°C |
Shipped In | Ice chest + Ice pads |
Product Description | IA-Alkyne is a TRP channel (TRPC) agonist and has the potential for the study of respiratory infection. IA-Alkyne can be used to develop an isotopically tagged probe for quantitative cysteine-reactivity profiling. |
Mechanism of Action | Action Type | target ID | Target Name | Target Type | Target Organism | Binding Site Name | References |
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Pubchem Sid | 504770346 |
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Pubchem Sid Url | https://pubchem.ncbi.nlm.nih.gov/substance/504770346 |
IUPAC Name | N-hex-5-ynyl-2-iodoacetamide |
INCHI | InChI=1S/C8H12INO/c1-2-3-4-5-6-10-8(11)7-9/h1H,3-7H2,(H,10,11) |
InChi Key | YCRUVTMZPHEOAM-UHFFFAOYSA-N |
Canonical SMILES | C#CCCCCNC(=O)CI |
Isomeric SMILES | C#CCCCCNC(=O)CI |
PubChem CID | 44448710 |
Molecular Weight | 265.09 |
Find and download the COA for your product by matching the lot number on the packaging.
9 results found
Lot Number | Certificate Type | Date | Item |
---|---|---|---|
Certificate of Analysis | May 23, 2023 | I287459 | |
Certificate of Analysis | May 23, 2023 | I287459 | |
Certificate of Analysis | May 23, 2023 | I287459 | |
Certificate of Analysis | May 23, 2023 | I287459 | |
Certificate of Analysis | May 23, 2023 | I287459 | |
Certificate of Analysis | May 23, 2023 | I287459 | |
Certificate of Analysis | May 23, 2023 | I287459 | |
Certificate of Analysis | May 23, 2023 | I287459 | |
Certificate of Analysis | May 23, 2023 | I287459 |
Solubility | Solvent:DMSO, Max Conc. mg/mL: 26.51, Max Conc. mM: 100; Solvent:ethanol, Max Conc. mg/mL: 26.51, Max Conc. mM: 100 |
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Sensitivity | Light sensitive |
Molecular Weight | 265.090 g/mol |
XLogP3 | 1.500 |
Hydrogen Bond Donor Count | 1 |
Hydrogen Bond Acceptor Count | 1 |
Rotatable Bond Count | 5 |
Exact Mass | 264.996 Da |
Monoisotopic Mass | 264.996 Da |
Topological Polar Surface Area | 29.100 Ų |
Heavy Atom Count | 11 |
Formal Charge | 0 |
Complexity | 159.000 |
Isotope Atom Count | 0 |
Defined Atom Stereocenter Count | 0 |
Undefined Atom Stereocenter Count | 0 |
Defined Bond Stereocenter Count | 0 |
Undefined Bond Stereocenter Count | 0 |
The total count of all stereochemical bonds | 0 |
Covalently-Bonded Unit Count | 1 |