Click Here for 5% Off Your First Aladdin Purchase!

N-Methyl morpholine - reagent grade,98%, high purity , CAS No.109-02-4

  • CP
  • ≥98%
Item Number
M104641
Grouped product items
SKUSizeAvailabilityPrice Qty
M104641-100ml
100ml
In stock
$25.90
M104641-500ml
500ml
In stock
$37.90

Basic Description

Synonyms4-Methylmorpholine|N-METHYLMORPHOLINE|109-02-4|Morpholine, 4-methyl-|Methylmorpholine|1-Methylmorpholine|N-methyl morpholine|4-methylmorpholin|Morpholine, N-methyl-|4-Methylmorfolin|NSC 9382|4-methyl-morpholine|11P91ANU5X|NMM|DTXSID9029146|NSC-9382|DTXCID
Specifications & PurityCP, ≥98%
Storage TempProtected from light,Room temperature
Shipped InNormal
GradeCP

Names and Identifiers

Pubchem Sid488180631
Pubchem Sid Urlhttps://pubchem.ncbi.nlm.nih.gov/substance/488180631
IUPAC Name 4-methylmorpholine
INCHI InChI=1S/C5H11NO/c1-6-2-4-7-5-3-6/h2-5H2,1H3
InChi Key SJRJJKPEHAURKC-UHFFFAOYSA-N
Canonical SMILES CN1CCOCC1
Isomeric SMILES CN1CCOCC1
WGK Germany 1
RTECS QE5775000
PubChem CID 7972
UN Number 2535
Packing Group II
Molecular Weight 101.15
Beilstein 102719

Certificates

Certificate of Analysis(COA)

Enter Lot Number to search for COA:

To view the certificate results,please click on a Lot number.For Lot numbers from past orders,please use our order status section

12 results found

Lot NumberCertificate TypeDateItem
L2122532Certificate of AnalysisSep 21, 2023 M104641
L2122535Certificate of AnalysisSep 21, 2023 M104641
E2424040Certificate of AnalysisJul 28, 2023 M104641
G2321885Certificate of AnalysisJul 28, 2023 M104641
G2321886Certificate of AnalysisJul 28, 2023 M104641
D23181177Certificate of AnalysisApr 21, 2023 M104641
D23181229Certificate of AnalysisApr 21, 2023 M104641
G2103014Certificate of AnalysisApr 12, 2023 M104641
A2306259Certificate of AnalysisJan 11, 2023 M104641
K2228284Certificate of AnalysisDec 01, 2022 M104641
L2009042Certificate of AnalysisSep 19, 2022 M104641
F2225388Certificate of AnalysisDec 27, 2021 M104641

more

Chemical and Physical Properties

SolubilityMiscible with water, soluble in benzene.
SensitivityLight sensitive.
Refractive Index1.4332
Flash Point(°F)14 ℃
Flash Point(°C)14 ℃
Boil Point(°C)111-114°C
Melt Point(°C)-65°C

Safety and Hazards(GHS)

Pictogram(s) GHS05,   GHS07,   GHS02
Signal Danger
Hazard Statements

H373:Causes damage to organs through prolonged or repeated exposure

H314:Causes severe skin burns and eye damage

H302:Harmful if swallowed

H318:Causes serious eye damage

H225:Highly Flammable liquid and vapor

H312:Harmful in contact with skin

H332:Harmful if inhaled

Precautionary Statements

P261:Avoid breathing dust/fume/gas/mist/vapors/spray.

P280:Wear protective gloves/protective clothing/eye protection/face protection.

P370+P378:In case of fire: Use ... to extinguish.

P210:Keep away from heat, hot surface, sparks, open flames and other ignition sources. - No smoking.

P302+P352:IF ON SKIN: wash with plenty of water.

P321:Specific treatment (see ... on this label).

P405:Store locked up.

P501:Dispose of contents/container to ...

P233:Keep container tightly closed.

P240:Ground/bond container and receiving equipment.

P264:Wash hands [and …] thoroughly after handling.

P403+P235:Store in a well-ventilated place. Keep cool.

P260:Do not breathe dust/fume/gas/mist/vapors/spray.

P303+P361+P353:IF ON SKIN (or hair): Take off Immediately all contaminated clothing. Rinse SKIN with water [or shower].

P271:Use only outdoors or in a well-ventilated area.

P241:Use explosion-proof [electrical/ventilating/lighting/.../] equipment.

P270:Do not eat, drink or smoke when using this product.

P301+P330+P331:IF SWALLOWED: Rinse mouth. Do NOT induce vomiting.

P304+P340:IF INHALED: Remove person to fresh air and keep comfortable for breathing.

P363:Wash contaminated clothing before reuse.

P362+P364:Take off contaminated clothing and wash it before reuse.

P330:Rinse mouth.

P242:Use only non-sparking tools.

P243:Take precautionary measures against static discharge.

P264+P265:Wash hands [and …] thoroughly after handling. Do not touch eyes.

P301+P317:IF SWALLOWED: Get medical help.

P305+P354+P338:IF IN EYES: Immediately rinse with water for several minutes. Remove contact lenses if present and easy to do. Continue rinsing.

P317:Get emergency medical help.

P302+P361+P354:IF ON SKIN: Take off Immediately all contaminated clothing. Immediately rinse with water for several minutes.

P316:Get emergency medical help immediately.

P319:Get medical help if you feel unwell.

WGK Germany 1
RTECS QE5775000
Class 3, 8
Merck Index 6277

Related Documents

References

1. Orbe J, Rodríguez JA, Sánchez-Arias JA, Salicio A, Belzunce M, Ugarte A, Chang HC, Rabal O, Oyarzabal J, Páramo JA.  (2015)  Discovery and safety profiling of a potent preclinical candidate, (4-[4-[[(3R)-3-(hydroxycarbamoyl)-8-azaspiro[4.5]decan-3-yl]sulfonyl]phenoxy]-N-methylbenzamide) (CM-352), for the prevention and treatment of hemorrhage..  J Med Chem,  58  (7): (2941-57).  [PMID:25686022]
2. B Lindegård,J A Jönsson,L Mathiasson.  (1992-01-17)  Liquid membrane work-up of blood plasma samples applied to gas chromatographic determination of aliphatic amines..  Journal of chromatography,  573  ((2)): (191-200).  [PMID:1601951]
3. L Hansén,B Akesson,J Sollenberg,T Lundh.  (1986-02-01)  Determination of N-methylmorpholine in air samples from a polyurethane foam factory. Comparison between two methods using gas chromatography and isotachophoresis for analysis..  Scandinavian journal of work, environment & health,  12  ((1)): (66-69).  [PMID:3961443]
4. B Mo,J Li,S Liang.  (1997-11-05)  Chemical carboxy-terminal sequence analysis of peptides using acetyl isothiocyanate..  Analytical biochemistry,  252  ((1)): (169-176).  [PMID:9324956]
5. K Sitarek.  (1999-12-10)  Maternal and fetal toxicity of N-methylmorpholine by oral administration in rats..  Teratogenesis, carcinogenesis, and mutagenesis,  19  ((6)): (369-376).  [PMID:10587407]
6. Denise S Ruzene,Daniel P Silva,António A Vicente,José A Teixeira,Maria T Pessoa de Amorim,Adilson R Gonçalves.  (2009-02-14)  Cellulosic films obtained from the treatment of sugarcane bagasse fibers with N-methylmorpholine-N-oxide (NMMO)..  Applied biochemistry and biotechnology,  154  ((1-3)): (38-47).  [PMID:19214797]
7. Mahdi Khodaverdi,Azam Jeihanipour,Keikhosro Karimi,Mohammad J Taherzadeh.  (2011-11-05)  Kinetic modeling of rapid enzymatic hydrolysis of crystalline cellulose after pretreatment by NMMO..  Journal of industrial microbiology & biotechnology,  39  ((3)): (429-438).  [PMID:22052078]
8. Jae H Park,Kevin P Carlin,Gang Wu,Victor I Ilyin,Donald J Kyle.  (2012-05-19)  Cysteine racemization during the Fmoc solid phase peptide synthesis of the Nav1.7-selective peptide--protoxin II..  Journal of peptide science : an official publication of the European Peptide Society,  18  ((7)): (442-448).  [PMID:22605564]
9. V Balachandran,G Mahalakshmi,A Lakshmi,A Janaki.  (2012-08-30)  DFT, FT-Raman, FT-IR, HOMO-LUMO and NBO studies of 4-Methylmorpholine..  Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy,  97  (1101-1110).  [PMID:22929905]
10. Yinghuan Li,Xuelian Zheng,Yi Sun,Zhao Ren,Xuemei Li,Guohui Cui.  (2014-04-09)  RGD-fatty alcohol-modified docetaxel liposomes improve tumor selectivity in vivo..  International journal of pharmaceutics,  468  ((1-2)): (133-141).  [PMID:24709214]
11. Hyo Jin Kang,Ju Hwan Kim,Sang J Chung.  (2014-09-15)  Homogeneous detection of caspase-3 using intrinsic fluorescence resonance energy transfer (iFRET)..  Biosensors & bioelectronics,  67  (413-418).  [PMID:25218199]
12. Antonia Patruno,Erika Fornasari,Antonio Di Stefano,Laura S Cerasa,Lisa Marinelli,Leonardo Baldassarre,Piera Sozio,Hasan Turkez,Sara Franceschelli,Alessio Ferrone,Viviana Di Giacomo,Lorenza Speranza,Mario Felaco,Ivana Cacciatore.  (2014-11-07)  Synthesis of a novel cyclic prodrug of S-allyl-glutathione able to attenuate LPS-induced ROS production through the inhibition of MAPK pathways in U937 cells..  Molecular pharmaceutics,  12  ((1)): (66-74).  [PMID:25375771]
13. Ling Hao,Xuefei Zhong,Tyler Greer,Hui Ye,Lingjun Li.  (2014-11-28)  Relative quantification of amine-containing metabolites using isobaric N,N-dimethyl leucine (DiLeu) reagents via LC-ESI-MS/MS and CE-ESI-MS/MS..  The Analyst,  140  ((2)): (467-475).  [PMID:25429371]
14. Michael R Pope,Sherry D Fleming.  (2014-12-30)  TLR2 modulates antibodies required for intestinal ischemia/reperfusion-induced damage and inflammation..  Journal of immunology (Baltimore, Md. : 1950),  194  ((3)): (1190-1198).  [PMID:25539820]
15. Delphine Knittel,Alexandra Savatier,Grégory Upert,Hugues Lortat-Jacob,Michel Léonetti.  (2015-03-11)  Acidosis increases MHC class II-restricted presentation of a protein endowed with a pH-dependent heparan sulfate-binding ability..  Journal of immunology (Baltimore, Md. : 1950),  194  ((8)): (3601-3611).  [PMID:25754736]
16. Evgeni Eltzov,Avital Cohen,Robert S Marks.  (2015-03-17)  Bioluminescent liquid light guide pad biosensor for indoor air toxicity monitoring..  Analytical chemistry,  87  ((7)): (3655-3661).  [PMID:25775008]
17. Susana Ramírez-Guízar,Hannah Sykes,John D Perry,Edward C Schwalbe,Stephen P Stanforth,Ma Cristina I Perez-Perez,John R Dean.  (2017-04-26)  A chromatographic approach to distinguish Gram-positive from Gram-negative bacteria using exogenous volatile organic compound metabolites..  Journal of chromatography. A,  1501  (79-88).  [PMID:28438317]
18. L Belin,U Wass,G Audunsson,L Mathiasson.  (1983-08-01)  Amines: possible causative agents in the development of bronchial hyperreactivity in workers manufacturing polyurethanes from isocyanates..  British journal of industrial medicine,  40  ((3)): (251-257).  [PMID:6307337]

Solution Calculators