N-Methyl-N-(trimethylsilyl)trifluoroacetamide - for derivatization, high purity , CAS No.24589-78-4

4 Citations
Item Number
M122796
Grouped product items
SKUSizeAvailabilityPrice Qty
M122796-1ml
1ml
Available within 4-8 weeks(?)
Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience!
$181.90

Discover N-Methyl-N-(trimethylsilyl)trifluoroacetamide by Aladdin Scientific in for derivatization for only $181.90. Available - in Ligands at Aladdin Scientific. Tags: .

Basic Description

SynonymsEINECS 246-331-6 | AS-17584 | N-Trimethylsilyl-N-methyl trifluoroacetamide | FT-0647484 | MSTFA Reagent | N-Methyltrifluoroacetamide, TMS derivative | Q27158313 | DTXSID5067003 | N-Methyl-N-(trimethyl-d9-silyl)trifluoroacetamide | A817383 | N-Methyl-N-(tr
Specifications & Purityfor GC derivatization
Storage TempStore at 2-8°C,Argon charged
Shipped InWet ice
Gradefor GC derivatization
Product Description

N-Methyl-N-(trimethylsilyl)trifluoroacetamide (MSTFA) is a silylating reagent.
Suitable for the derivatization of amines, amino acids, carboxyl, hydroxyamines, indolalkylamine, n-nitrosoamino acids, nucleosides, phenolalkylamines, serotonin and tryptamine.
MSTFA may be used in silylation procedure to detemine steroid hormones 17α-ethinylestradiol (EE2) and estrone using GC-MS. MSTFA along with Trimethylsilyl chloride (TMCS) in eithyl acetate, acetonitrile and dichloromethane solvents leads to formation of trimethylsilyl (TMS) and tert-butyldimethylsilyl (TBS) derivatives.
Powerful silylating agent
Reagent for N-acetyl-N, trifluoroacetyl, trimethylsilyl, N-trimethylsilyl-N-trifluoroacetyl, and O-trimethylsilyl (TMS)

Names and Identifiers

IUPAC Name 2,2,2-trifluoro-N-methyl-N-trimethylsilylacetamide
INCHI InChI=1S/C6H12F3NOSi/c1-10(12(2,3)4)5(11)6(7,8)9/h1-4H3
InChi Key MSPCIZMDDUQPGJ-UHFFFAOYSA-N
Canonical SMILES CN(C(=O)C(F)(F)F)[Si](C)(C)C
Isomeric SMILES CN(C(=O)C(F)(F)F)[Si](C)(C)C
WGK Germany 3
PubChem CID 32510
Molecular Weight 199.25
Beilstein 1941550

Certificates

Certificate of Analysis(COA)

Enter Lot Number to search for COA:

Find and download the COA for your product by matching the lot number on the packaging.

3 results found

Lot NumberCertificate TypeDateItem
A2207903Certificate of AnalysisOct 12, 2023 M122796
F2207126Certificate of AnalysisMar 11, 2022 M122796
F2207157Certificate of AnalysisMar 11, 2022 M122796

Chemical and Physical Properties

SolubilityImmiscible with water.
SensitivityHygroscopic
Refractive Index1.38
Flash Point(°F)78.8 °F
Flash Point(°C)26 °C
Boil Point(°C)130-132°C

Safety and Hazards(GHS)

Pictogram(s) GHS07,   GHS02
Signal Warning
Hazard Statements

H315:Causes skin irritation

H319:Causes serious eye irritation

H335:May cause respiratory irritation

H226:Flammable liquid and vapor

Precautionary Statements

P261:Avoid breathing dust/fume/gas/mist/vapors/spray.

P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses if present and easy to do - continue rinsing.

P280:Wear protective gloves/protective clothing/eye protection/face protection.

P370+P378:In case of fire: Use ... to extinguish.

P210:Keep away from heat, hot surface, sparks, open flames and other ignition sources. - No smoking.

P302+P352:IF ON SKIN: wash with plenty of water.

P321:Specific treatment (see ... on this label).

P405:Store locked up.

P501:Dispose of contents/container to ...

P233:Keep container tightly closed.

P240:Ground/bond container and receiving equipment.

P264:Wash hands [and …] thoroughly after handling.

P403+P235:Store in a well-ventilated place. Keep cool.

P303+P361+P353:IF ON SKIN (or hair): Take off Immediately all contaminated clothing. Rinse SKIN with water [or shower].

P271:Use only outdoors or in a well-ventilated area.

P241:Use explosion-proof [electrical/ventilating/lighting/.../] equipment.

P304+P340:IF INHALED: Remove person to fresh air and keep comfortable for breathing.

P403+P233:Store in a well-ventilated place. Keep container tightly closed.

P362+P364:Take off contaminated clothing and wash it before reuse.

P242:Use only non-sparking tools.

P243:Take precautionary measures against static discharge.

P264+P265:Wash hands [and …] thoroughly after handling. Do not touch eyes.

P337+P317:If eye irritation persists: Get medical help.

P332+P317:If skin irritation occurs: Get medical help.

P319:Get medical help if you feel unwell.

WGK Germany 3

Related Documents

Citations of This Product

1. Hailing Huang, Bailu Duan, Sili Zheng, Yan Ye, Dongning Zhang, Zhuang Huang, Shanshan Wang, Fengyun Zhang, Ping Huang, Fang Huang, Lintao Han.  (2023)  Integrated network pharmacology and metabolomics analyses of the mechanism underlying the efficacy of Ma-Mu-Ran Antidiarrheal Capsules against dextran sulfate sodium–induced ulcerative colitis.  BIOMEDICAL CHROMATOGRAPHY,  37  (11): (e5732).  [PMID:37732359]
2. Xianxiu Li, Tao He, Yangchen Mao, Jianwei Mao, Xiaojin Lai, Hangjia Tu, Yi Zhou, Ruyi Sha.  (2023)  Changes in Physicochemical Properties, Metabolites and Antioxidant Activity of Edible Grass during Spontaneous Fermentation.  Fermentation-Basel,  (4): (377).  [PMID:]
3. Dongning Zhang, Bailu Duan, Li Sun, Yanfen Duan, Sili Zheng, Jingjing Li, Hailong Yin, Dandan Mu, Shuaihong Hou, Guoyan Mo, Lintao Han, Fang Huang, Qiang Yin.  (2022)  Mechanism of Shiliu Buxue Syrup for anemia using integrated metabolomics and network pharmacology.  ANALYTICAL BIOCHEMISTRY,      [PMID:35690102]
4. Guo Mei, Wu Zhicong, An Qi, Li Hengyang, Wang Lei, Zheng Yuguang, Guo Long, Zhang Dan.  (2021)  Comparison of Volatile Oils and Primary Metabolites of Raw and Honey-Processed Ephedrae Herba by GC–MS and Chemometrics.  JOURNAL OF AOAC INTERNATIONAL,  105  (2): (576-586).  [PMID:34626113]
5. Jin-Xiu Liang, Qun-Qun Zhang, Yan-Fei Huang, Han-Qing Pang, Xin-Guang Liu, Wen Gao, Ping Li, Hua Yang.  (2019)  Comprehensive chemical profiling of monascus-fermented rice product and screening of lipid-lowering compounds other than monacolins.  JOURNAL OF ETHNOPHARMACOLOGY,  238  (111879).  [PMID:30991138]

References

1. Hailing Huang, Bailu Duan, Sili Zheng, Yan Ye, Dongning Zhang, Zhuang Huang, Shanshan Wang, Fengyun Zhang, Ping Huang, Fang Huang, Lintao Han.  (2023)  Integrated network pharmacology and metabolomics analyses of the mechanism underlying the efficacy of Ma-Mu-Ran Antidiarrheal Capsules against dextran sulfate sodium–induced ulcerative colitis.  BIOMEDICAL CHROMATOGRAPHY,  37  (11): (e5732).  [PMID:37732359]
2. Xianxiu Li, Tao He, Yangchen Mao, Jianwei Mao, Xiaojin Lai, Hangjia Tu, Yi Zhou, Ruyi Sha.  (2023)  Changes in Physicochemical Properties, Metabolites and Antioxidant Activity of Edible Grass during Spontaneous Fermentation.  Fermentation-Basel,  (4): (377).  [PMID:]
3. Dongning Zhang, Bailu Duan, Li Sun, Yanfen Duan, Sili Zheng, Jingjing Li, Hailong Yin, Dandan Mu, Shuaihong Hou, Guoyan Mo, Lintao Han, Fang Huang, Qiang Yin.  (2022)  Mechanism of Shiliu Buxue Syrup for anemia using integrated metabolomics and network pharmacology.  ANALYTICAL BIOCHEMISTRY,      [PMID:35690102]
4. Guo Mei, Wu Zhicong, An Qi, Li Hengyang, Wang Lei, Zheng Yuguang, Guo Long, Zhang Dan.  (2021)  Comparison of Volatile Oils and Primary Metabolites of Raw and Honey-Processed Ephedrae Herba by GC–MS and Chemometrics.  JOURNAL OF AOAC INTERNATIONAL,  105  (2): (576-586).  [PMID:34626113]
5. Jin-Xiu Liang, Qun-Qun Zhang, Yan-Fei Huang, Han-Qing Pang, Xin-Guang Liu, Wen Gao, Ping Li, Hua Yang.  (2019)  Comprehensive chemical profiling of monascus-fermented rice product and screening of lipid-lowering compounds other than monacolins.  JOURNAL OF ETHNOPHARMACOLOGY,  238  (111879).  [PMID:30991138]

Solution Calculators