N-Methylthiourea - 98%, high purity , CAS No.598-52-7

  • ≥98%
Item Number
M102026
Grouped product items
SKUSizeAvailabilityPrice Qty
M102026-5g
5g
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$12.90
M102026-25g
25g
In stock
$36.90
M102026-100g
100g
In stock
$109.90
M102026-500g
500g
Available within 4-8 weeks(?)
Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience!
$491.90

Basic Description

SynonymsN-Methylthiourea, 97% | STL122193 | NSC30213 | NSC-30213 | 1-Methylthiocarbamide | FT-0647492 | Methylthiocarbamide | methylisothiourea | 2-Chloro-6-methoxyquinoline-3-carbaldehydeoxime | DTXSID90208533 | Methylthiourea | methyl-thiourea | HRK3DMO87X | CH
Specifications & Purity≥98%
Shipped InNormal
Product Description

N-Methylthiourea can be used as a novel coolant composition for electric vehicle.

Mechanisms of Action

Mechanism of ActionAction Typetarget IDTarget NameTarget TypeTarget OrganismBinding Site NameReferences

Names and Identifiers

IUPAC Name methylthiourea
INCHI InChI=1S/C2H6N2S/c1-4-2(3)5/h1H3,(H3,3,4,5)
InChi Key KQJQICVXLJTWQD-UHFFFAOYSA-N
Canonical SMILES CNC(=S)N
Isomeric SMILES CNC(=S)N
WGK Germany 3
RTECS YT9000000
PubChem CID 2723704
Molecular Weight 90.15
Beilstein 506162
Reaxy-Rn 506162

Certificates

Certificate of Analysis(COA)

Enter Lot Number to search for COA:

Find and download the COA for your product by matching the lot number on the packaging.

6 results found

Lot NumberCertificate TypeDateItem
D2407386Certificate of AnalysisMar 11, 2024 M102026
E2410183Certificate of AnalysisMar 11, 2024 M102026
D2215044Certificate of AnalysisMar 03, 2022 M102026
D2215045Certificate of AnalysisMar 03, 2022 M102026
D2215048Certificate of AnalysisMar 03, 2022 M102026
I2423662Certificate of AnalysisMar 03, 2022 M102026

Chemical and Physical Properties

SolubilitySoluble in water; Degree of Solubility in water: 165 g/l 20 °C
Melt Point(°C)120°C

Safety and Hazards(GHS)

Pictogram(s) GHS06,   GHS08
Signal Danger
Hazard Statements

H300:Fatal if swallowed

H361:Suspected of damaging fertility or the unborn child

Precautionary Statements

P280:Wear protective gloves/protective clothing/eye protection/face protection.

P321:Specific treatment (see ... on this label).

P405:Store locked up.

P501:Dispose of contents/container to ...

P264:Wash hands [and …] thoroughly after handling.

P270:Do not eat, drink or smoke when using this product.

P330:Rinse mouth.

P203:Obtain, read and follow all safety instructions before use.

P301+P316:IF SWALLOWED: Get emergency medical help immediately.

P318:if exposed or concerned, get medical advice.

WGK Germany 3
RTECS YT9000000
Reaxy-Rn 506162

Related Documents

Citations of This Product

1. Zhenkun Mao, Jinxiu Chen, Dandan Jiang, Ningmin Zhao, Yinhui Qin, Xiangju Mao, Fengqin Fang, Peizhi Ma.  (2024)  Itaconic Acid-Based Organic-Polymer Monolithic Column for Hydrophilic Capillary Electrochromatography and Its Application in Pharmaceutical Analysis.  ACS Omega,  (1): (1554–1561).  [PMID:38222631] [10.1021/acsomega.3c08031]
2. Wei Yaru, Zhang Kaili, Cheng Tiexin, Zhou Guangdong.  (2023)  Characteristics and Mechanisms of Cr(VI) Removal from Aqueous Solution by FeSm/BC Composite.  WATER AIR AND SOIL POLLUTION,  234  (2): (1-13).  [PMID:] [10.1007/s11270-023-06084-3]
3. Shengming Xu, Jing Xu, Linying Hu, Ye Liu, Lijun Ma.  (2021)  S-Scheme heterojunction based on the in situ coated core–shell NiCo2S4@WS2 photocatalyst was constructed for efficient photocatalytic hydrogen evolution.  NEW JOURNAL OF CHEMISTRY,  46  (1): (57-69).  [PMID:] [10.1039/D1NJ04409E]
4. Xuhong Jiang, Mengmeng Sun, Zhuoyuan Chen, Jiangping Jing, Guiying Lu, Chang Feng.  (2021)  Boosted photoinduced cathodic protection performance of ZnIn2S4/TiO2 nanoflowerbush with efficient photoelectric conversion in NaCl solution.  JOURNAL OF ALLOYS AND COMPOUNDS,  876  (160144).  [PMID:] [10.1016/j.jallcom.2021.160144]
5. Xiaoyun Chen, Huizhi Sun, Dong-Hau Kuo, Adugna Boke Abdeta, Osman Ahmed Zelekew, Yuanbo Guo, Jubin Zhang, Zhanhui Yuan, Jinguo Lin.  (2021)  Spherical nanoflower-like bimetallic (Mo,Ni)(S,O)3-x sulfo-oxide catalysts for efficient hydrogen evolution under visible light.  APPLIED CATALYSIS B-ENVIRONMENTAL,  287  (119992).  [PMID:] [10.1016/j.apcatb.2021.119992]
6. Yu Haitao, Xue Zhimin, Lan Xue, Liu Qiaoling, Shi Ruifen, Mu Tiancheng.  (2020)  Highly efficient dissolution of xylan in ionic liquid-based deep eutectic solvents.  CELLULOSE,  27  (11): (6175-6188).  [PMID:] [10.1007/s10570-020-03213-7]
7. Chen Zhi, Chen Suilong, Zhang Hanfu, Liu Mingqiang, Feng Zhjun, Li Xibao, Huang Juntong, Guo Di.  (2020)  Exfoliated MoS2@C nanosheets as anode for sodium/potassium storage.  IONICS,  26  (4): (1779-1786).  [PMID:] [10.1007/s11581-019-03351-4]
8. Qiaoling Liu, Hongyu Mou, Wenjun Chen, Xinhui Zhao, Haitao Yu, Zhimin Xue, Tiancheng Mu.  (2019)  Highly Efficient Dissolution of Lignin by Eutectic Molecular Liquids.  INDUSTRIAL & ENGINEERING CHEMISTRY RESEARCH,  58  (51): (23438–23444).  [PMID:] [10.1021/acs.iecr.9b05059]
9. Xiaolei Zhao, Yu He, Yanan Wang, Shuo Wang, Junping Wang.  (2020)  Hollow molecularly imprinted polymer based quartz crystal microbalance sensor for rapid detection of methimazole in food samples.  FOOD CHEMISTRY,  309  (125787).  [PMID:31771917] [10.1016/j.foodchem.2019.125787]
10. Tingting Wang.  (2018)  Polyethyleneimine-modified hybrid silica sorbent for hydrophilic solid-phase extraction of thyreostats in animal tissues.  JOURNAL OF CHROMATOGRAPHY A,  1581-1582  (16).  [PMID:30424967] [10.1016/j.chroma.2018.11.006]
11. Ka Wang, Weilan Guo, Shancheng Yan, Haizeng Song, Yi Shi.  (2018)  Hierarchical Co–FeS2/CoS2 heterostructures as a superior bifunctional electrocatalyst.  RSC Advances,  (50): (28684-28691).  [PMID:35542473] [10.1039/C8RA05237A]
12. Weili Dai, Wanyuan Yang, Ya Zhang, Dan Wang, Xubiao Luo, Xinman Tu.  (2017)  Novel isothiouronium ionic liquid as efficient catalysts for the synthesis of cyclic carbonates from CO2 and epoxides.  Journal of CO2 Utilization,  17  (256).  [PMID:] [10.1016/j.jcou.2016.12.010]

References

1. S P Gorman,D F McCafferty,A D Woolfson,L Anderson.  (1986-04-01)  Decrease in adherence of bacteria and yeasts to human mucosal epithelial cells by noxythiolin in vitro..  The Journal of applied bacteriology,  60  ((4)): (311-317).  [PMID:3087930]
2. S P Gorman,D F McCafferty,A D Woolfson,L Anderson.  (1985-06-01)  A comparison of the antimicrobial activities of noxythiolin and formaldehyde solutions..  Journal of clinical and hospital pharmacy,  10  ((2)): (185-192).  [PMID:3926827]
3. J Maldonado,J Haring,M Lanza.  (1980-05-01)  [Proper use of noxythiolin: an experimental rat study on interaction with lactic acid]..  Therapie,  35  ((3)): (409-412).  [PMID:6775385]
4. M Yabuki,J Shimakura,M Ito,H Kanamaru,K Iba,I Nakatsuka.  (1997-01-01)  Metabolism of 4-[1-(2-fluoro-4-biphenylyl)ethyl]-2-methylaminothiazole (SM-8849) in rats..  European journal of drug metabolism and pharmacokinetics,  22  ((1)): (25-33).  [PMID:9179557]
5. T Mizutani,K Yoshida,M Murakami,M Shirai,S Kawazoe.  (2000-03-22)  Evidence for the involvement of N-methylthiourea, a ring cleavage metabolite, in the hepatotoxicity of methimazole in glutathione-depleted mice: structure-toxicity and metabolic studies..  Chemical research in toxicology,  13  ((3)): (170-176).  [PMID:10725113]
6. Reza Heidari,Hossein Babaei,Mohammad Ali Eghbal.  (2012-12-25)  Ameliorative effects of taurine against methimazole-induced cytotoxicity in isolated rat hepatocytes..  Scientia pharmaceutica,  80  ((4)): (987-999).  [PMID:23264945]
7. Shruti Sharma,Xutong Sun,Saurabh Agarwal,Ruslan Rafikov,Sridevi Dasarathy,Sanjiv Kumar,Stephen M Black.  (2013-01-25)  Role of carnitine acetyl transferase in regulation of nitric oxide signaling in pulmonary arterial endothelial cells..  International journal of molecular sciences,  14  ((1)): (255-272).  [PMID:23344032]
8. Christine M Gross,Ruslan Rafikov,Sanjiv Kumar,Saurabh Aggarwal,P Benson Ham,Mary Louise Meadows,Mary Cherian-Shaw,Archana Kangath,Supriya Sridhar,Rudolf Lucas,Stephen M Black.  (2015-03-19)  Endothelial nitric oxide synthase deficient mice are protected from lipopolysaccharide induced acute lung injury..  PloS one,  10  ((3)): (e0119918-e0119918).  [PMID:25786132]
9. Renata Studzińska,Renata Kołodziejska,Wojciech Płaziński,Daria Kupczyk,Tomasz Kosmalski,Katarzyna Jasieniecka,Bożena Modzelewska-Banachiewicz.  (2019-04-24)  Synthesis of the N-methyl Derivatives of 2-Aminothiazol-4(5H)-one and Their Interactions with 11βHSD1-Molecular Modeling and in Vitro Studies..  Chemistry & biodiversity,  16  ((6)): (e1900065-e1900065).  [PMID:31012543]
10. S P Gorman,D F McCafferty,A D Woolfson,L Anderson.  (1986-04-01)  Inhibition of hyphal development and kill of Candida albicans blastospores by noxythiolin in vitro..  The Journal of applied bacteriology,  60  ((4)): (319-325).  [PMID:3087931]
11. D Debruyne,M A Moulin,H Bricard,M C Bigot.  (1985-02-01)  Liquid chromatographic determination of noxytiolin and 1-methyl-2-thiourea in serum: application to pharmacokinetic studies in rabbits and humans..  Journal of pharmaceutical sciences,  74  ((2)): (224-226).  [PMID:3921689]
12. D F McCafferty,K Furness,L Anderson.  (1984-09-01)  Stability of noxythiolin solutions stored in plastic and glass containers..  Journal of clinical and hospital pharmacy,  ((3)): (241-247).  [PMID:6436322]
13. H Kobayashi,M Kaneda,S Teramoto.  (1982-07-01)  Identification of 1-methylthiourea as the metabolite of ethylenethiourea in rats by high-performance liquid chromatography..  Toxicology letters,  12  ((2-3)): (109-113).  [PMID:6810507]
14. Eiko Satoh,Iho Yasuda,Tomoko Yamada,Yasuyuki Suzuki,Takao Ohyashiki.  (2007-08-02)  Involvement of NO generation in aluminum-induced cell death..  Biological & pharmaceutical bulletin,  30  ((8)): (1390-1394).  [PMID:17666791]
15. Yohan Park,Suckchang Hong,Myungmo Lee,Hyojun Jung,Won-Jea Cho,Eun-Jin Kim,Ho-Young Son,Mi-Ock Lee,Hyeung-Geun Park.  (2012-09-04)  N-methylthioureas as new agonists of retinoic acid receptor-related orphan receptor..  Archives of pharmacal research,  35  ((8)): (1393-1401).  [PMID:22941482]
16. Shruti Sharma,Xutong Sun,Ruslan Rafikov,Sanjiv Kumar,Yali Hou,Peter E Oishi,Sanjeev A Datar,Gary Raff,Jeffrey R Fineman,Stephen M Black.  (2012-09-11)  PPAR-γ regulates carnitine homeostasis and mitochondrial function in a lamb model of increased pulmonary blood flow..  PloS one,  ((9)): (e41555-e41555).  [PMID:22962578]
17. Zhenkun Mao, Jinxiu Chen, Dandan Jiang, Ningmin Zhao, Yinhui Qin, Xiangju Mao, Fengqin Fang, Peizhi Ma.  (2024)  Itaconic Acid-Based Organic-Polymer Monolithic Column for Hydrophilic Capillary Electrochromatography and Its Application in Pharmaceutical Analysis.  ACS Omega,  (1): (1554–1561).  [PMID:38222631] [10.1021/acsomega.3c08031]
18. Wei Yaru, Zhang Kaili, Cheng Tiexin, Zhou Guangdong.  (2023)  Characteristics and Mechanisms of Cr(VI) Removal from Aqueous Solution by FeSm/BC Composite.  WATER AIR AND SOIL POLLUTION,  234  (2): (1-13).  [PMID:] [10.1007/s11270-023-06084-3]
19. Shengming Xu, Jing Xu, Linying Hu, Ye Liu, Lijun Ma.  (2021)  S-Scheme heterojunction based on the in situ coated core–shell NiCo2S4@WS2 photocatalyst was constructed for efficient photocatalytic hydrogen evolution.  NEW JOURNAL OF CHEMISTRY,  46  (1): (57-69).  [PMID:] [10.1039/D1NJ04409E]
20. Xuhong Jiang, Mengmeng Sun, Zhuoyuan Chen, Jiangping Jing, Guiying Lu, Chang Feng.  (2021)  Boosted photoinduced cathodic protection performance of ZnIn2S4/TiO2 nanoflowerbush with efficient photoelectric conversion in NaCl solution.  JOURNAL OF ALLOYS AND COMPOUNDS,  876  (160144).  [PMID:] [10.1016/j.jallcom.2021.160144]
21. Xiaoyun Chen, Huizhi Sun, Dong-Hau Kuo, Adugna Boke Abdeta, Osman Ahmed Zelekew, Yuanbo Guo, Jubin Zhang, Zhanhui Yuan, Jinguo Lin.  (2021)  Spherical nanoflower-like bimetallic (Mo,Ni)(S,O)3-x sulfo-oxide catalysts for efficient hydrogen evolution under visible light.  APPLIED CATALYSIS B-ENVIRONMENTAL,  287  (119992).  [PMID:] [10.1016/j.apcatb.2021.119992]
22. Yu Haitao, Xue Zhimin, Lan Xue, Liu Qiaoling, Shi Ruifen, Mu Tiancheng.  (2020)  Highly efficient dissolution of xylan in ionic liquid-based deep eutectic solvents.  CELLULOSE,  27  (11): (6175-6188).  [PMID:] [10.1007/s10570-020-03213-7]
23. Chen Zhi, Chen Suilong, Zhang Hanfu, Liu Mingqiang, Feng Zhjun, Li Xibao, Huang Juntong, Guo Di.  (2020)  Exfoliated MoS2@C nanosheets as anode for sodium/potassium storage.  IONICS,  26  (4): (1779-1786).  [PMID:] [10.1007/s11581-019-03351-4]
24. Qiaoling Liu, Hongyu Mou, Wenjun Chen, Xinhui Zhao, Haitao Yu, Zhimin Xue, Tiancheng Mu.  (2019)  Highly Efficient Dissolution of Lignin by Eutectic Molecular Liquids.  INDUSTRIAL & ENGINEERING CHEMISTRY RESEARCH,  58  (51): (23438–23444).  [PMID:] [10.1021/acs.iecr.9b05059]
25. Xiaolei Zhao, Yu He, Yanan Wang, Shuo Wang, Junping Wang.  (2020)  Hollow molecularly imprinted polymer based quartz crystal microbalance sensor for rapid detection of methimazole in food samples.  FOOD CHEMISTRY,  309  (125787).  [PMID:31771917] [10.1016/j.foodchem.2019.125787]
26. Tingting Wang.  (2018)  Polyethyleneimine-modified hybrid silica sorbent for hydrophilic solid-phase extraction of thyreostats in animal tissues.  JOURNAL OF CHROMATOGRAPHY A,  1581-1582  (16).  [PMID:30424967] [10.1016/j.chroma.2018.11.006]
27. Ka Wang, Weilan Guo, Shancheng Yan, Haizeng Song, Yi Shi.  (2018)  Hierarchical Co–FeS2/CoS2 heterostructures as a superior bifunctional electrocatalyst.  RSC Advances,  (50): (28684-28691).  [PMID:35542473] [10.1039/C8RA05237A]
28. Weili Dai, Wanyuan Yang, Ya Zhang, Dan Wang, Xubiao Luo, Xinman Tu.  (2017)  Novel isothiouronium ionic liquid as efficient catalysts for the synthesis of cyclic carbonates from CO2 and epoxides.  Journal of CO2 Utilization,  17  (256).  [PMID:] [10.1016/j.jcou.2016.12.010]

Solution Calculators