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Price

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M102026-5g

Available within 8-12 weeks(?)

$12.90

M102026-25g

25g

In stock

$36.90

M102026-100g

100g

In stock

$109.90

M102026-500g

500g

Available within 4-8 weeks(?)

$491.90

Basic Description

Synonyms	N-METHYLTHIOUREA \| 1-Methylthiourea \| 598-52-7 \| Methylthiourea \| 1-Methyl-2-thiourea \| Thiourea, methyl- \| Methylthiocarbamide \| Monomethylthiourea \| 1-Methylthiocarbamide \| N-Methylthiocarbamide \| Methyl thiourea \| Urea, 1-methyl-2-thio- \| methyl-thiourea \| Pseudourea, 1-methyl-
Specifications & Purity	≥98%
Shipped In	Normal
Product Description	N-Methylthiourea can be used as a novel coolant composition for electric vehicle.

Associated Targets(Human)

TAS2R38 Tchem Taste receptor type 2 member 38 (37 Activities)

Discover Target: TAS2R38

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Names and Identifiers

IUPAC Name	methylthiourea
INCHI	InChI=1S/C2H6N2S/c1-4-2(3)5/h1H3,(H3,3,4,5)
InChi Key	KQJQICVXLJTWQD-UHFFFAOYSA-N
Canonical SMILES	CNC(=S)N
Isomeric SMILES	CNC(=S)N
WGK Germany	3
RTECS	YT9000000
PubChem CID	2723704
Molecular Weight	90.15
Beilstein	506162
Reaxy-Rn	506162

Certificates

Certificate of Analysis(COA)

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5 results found

Lot Number	Certificate Type	Date	Item
D2407386	Certificate of Analysis	Mar 11, 2024	M102026
E2410183	Certificate of Analysis	Mar 11, 2024	M102026
D2215044	Certificate of Analysis	Mar 03, 2022	M102026
D2215045	Certificate of Analysis	Mar 03, 2022	M102026
D2215048	Certificate of Analysis	Mar 03, 2022	M102026

Chemical and Physical Properties

Solubility	Soluble in water; Degree of Solubility in water: 165 g/l 20 °C
Melt Point(°C)	120°C

Safety and Hazards(GHS)

Pictogram(s)	GHS06, GHS08
Signal	Danger
Hazard Statements	H300:Fatal if swallowed H361:Suspected of damaging fertility or the unborn child
Precautionary Statements	P280:Wear protective gloves/protective clothing/eye protection/face protection. P321:Specific treatment (see ... on this label). P405:Store locked up. P501:Dispose of contents/container to ... P264:Wash hands [and …] thoroughly after handling. P270:Do not eat, drink or smoke when using this product. P330:Rinse mouth. P203:Obtain, read and follow all safety instructions before use. P301+P316:IF SWALLOWED: Get emergency medical help immediately. P318:if exposed or concerned, get medical advice.
WGK Germany	3
RTECS	YT9000000
Reaxy-Rn	506162

Citations of This Product

1. Zhenkun Mao, Jinxiu Chen, Dandan Jiang, Ningmin Zhao, Yinhui Qin, Xiangju Mao, Fengqin Fang, Peizhi Ma. (2024) Itaconic Acid-Based Organic-Polymer Monolithic Column for Hydrophilic Capillary Electrochromatography and Its Application in Pharmaceutical Analysis. ACS Omega, 9 (1): (1554–1561). [PMID:38222631]
2. Wei Yaru, Zhang Kaili, Cheng Tiexin, Zhou Guangdong. (2023) Characteristics and Mechanisms of Cr(VI) Removal from Aqueous Solution by FeSm/BC Composite. WATER AIR AND SOIL POLLUTION, 234 (2): (1-13). [PMID:]
3. Shengming Xu, Jing Xu, Linying Hu, Ye Liu, Lijun Ma. (2021) S-Scheme heterojunction based on the in situ coated core–shell NiCo2S4@WS2 photocatalyst was constructed for efficient photocatalytic hydrogen evolution. NEW JOURNAL OF CHEMISTRY, 46 (1): (57-69). [PMID:]

References

1. S P Gorman,D F McCafferty,A D Woolfson,L Anderson. (1986-04-01) Decrease in adherence of bacteria and yeasts to human mucosal epithelial cells by noxythiolin in vitro.. The Journal of applied bacteriology, 60 ((4)): (311-317). [PMID:3087930]
2. S P Gorman,D F McCafferty,A D Woolfson,L Anderson. (1985-06-01) A comparison of the antimicrobial activities of noxythiolin and formaldehyde solutions.. Journal of clinical and hospital pharmacy, 10 ((2)): (185-192). [PMID:3926827]
3. J Maldonado,J Haring,M Lanza. (1980-05-01) [Proper use of noxythiolin: an experimental rat study on interaction with lactic acid].. Therapie, 35 ((3)): (409-412). [PMID:6775385]
4. M Yabuki,J Shimakura,M Ito,H Kanamaru,K Iba,I Nakatsuka. (1997-01-01) Metabolism of 4-[1-(2-fluoro-4-biphenylyl)ethyl]-2-methylaminothiazole (SM-8849) in rats.. European journal of drug metabolism and pharmacokinetics, 22 ((1)): (25-33). [PMID:9179557]
5. T Mizutani,K Yoshida,M Murakami,M Shirai,S Kawazoe. (2000-03-22) Evidence for the involvement of N-methylthiourea, a ring cleavage metabolite, in the hepatotoxicity of methimazole in glutathione-depleted mice: structure-toxicity and metabolic studies.. Chemical research in toxicology, 13 ((3)): (170-176). [PMID:10725113]
6. Reza Heidari,Hossein Babaei,Mohammad Ali Eghbal. (2012-12-25) Ameliorative effects of taurine against methimazole-induced cytotoxicity in isolated rat hepatocytes.. Scientia pharmaceutica, 80 ((4)): (987-999). [PMID:23264945]
7. Shruti Sharma,Xutong Sun,Saurabh Agarwal,Ruslan Rafikov,Sridevi Dasarathy,Sanjiv Kumar,Stephen M Black. (2013-01-25) Role of carnitine acetyl transferase in regulation of nitric oxide signaling in pulmonary arterial endothelial cells.. International journal of molecular sciences, 14 ((1)): (255-272). [PMID:23344032]
8. Christine M Gross,Ruslan Rafikov,Sanjiv Kumar,Saurabh Aggarwal,P Benson Ham,Mary Louise Meadows,Mary Cherian-Shaw,Archana Kangath,Supriya Sridhar,Rudolf Lucas,Stephen M Black. (2015-03-19) Endothelial nitric oxide synthase deficient mice are protected from lipopolysaccharide induced acute lung injury.. PloS one, 10 ((3)): (e0119918-e0119918). [PMID:25786132]
9. Renata Studzińska,Renata Kołodziejska,Wojciech Płaziński,Daria Kupczyk,Tomasz Kosmalski,Katarzyna Jasieniecka,Bożena Modzelewska-Banachiewicz. (2019-04-24) Synthesis of the N-methyl Derivatives of 2-Aminothiazol-4(5H)-one and Their Interactions with 11βHSD1-Molecular Modeling and in Vitro Studies.. Chemistry & biodiversity, 16 ((6)): (e1900065-e1900065). [PMID:31012543]
10. S P Gorman,D F McCafferty,A D Woolfson,L Anderson. (1986-04-01) Inhibition of hyphal development and kill of Candida albicans blastospores by noxythiolin in vitro.. The Journal of applied bacteriology, 60 ((4)): (319-325). [PMID:3087931]
11. D Debruyne,M A Moulin,H Bricard,M C Bigot. (1985-02-01) Liquid chromatographic determination of noxytiolin and 1-methyl-2-thiourea in serum: application to pharmacokinetic studies in rabbits and humans.. Journal of pharmaceutical sciences, 74 ((2)): (224-226). [PMID:3921689]
12. D F McCafferty,K Furness,L Anderson. (1984-09-01) Stability of noxythiolin solutions stored in plastic and glass containers.. Journal of clinical and hospital pharmacy, 9 ((3)): (241-247). [PMID:6436322]
13. H Kobayashi,M Kaneda,S Teramoto. (1982-07-01) Identification of 1-methylthiourea as the metabolite of ethylenethiourea in rats by high-performance liquid chromatography.. Toxicology letters, 12 ((2-3)): (109-113). [PMID:6810507]
14. Eiko Satoh,Iho Yasuda,Tomoko Yamada,Yasuyuki Suzuki,Takao Ohyashiki. (2007-08-02) Involvement of NO generation in aluminum-induced cell death.. Biological & pharmaceutical bulletin, 30 ((8)): (1390-1394). [PMID:17666791]
15. Yohan Park,Suckchang Hong,Myungmo Lee,Hyojun Jung,Won-Jea Cho,Eun-Jin Kim,Ho-Young Son,Mi-Ock Lee,Hyeung-Geun Park. (2012-09-04) N-methylthioureas as new agonists of retinoic acid receptor-related orphan receptor.. Archives of pharmacal research, 35 ((8)): (1393-1401). [PMID:22941482]
16. Shruti Sharma,Xutong Sun,Ruslan Rafikov,Sanjiv Kumar,Yali Hou,Peter E Oishi,Sanjeev A Datar,Gary Raff,Jeffrey R Fineman,Stephen M Black. (2012-09-11) PPAR-γ regulates carnitine homeostasis and mitochondrial function in a lamb model of increased pulmonary blood flow.. PloS one, 7 ((9)): (e41555-e41555). [PMID:22962578]
17. Zhenkun Mao, Jinxiu Chen, Dandan Jiang, Ningmin Zhao, Yinhui Qin, Xiangju Mao, Fengqin Fang, Peizhi Ma. (2024) Itaconic Acid-Based Organic-Polymer Monolithic Column for Hydrophilic Capillary Electrochromatography and Its Application in Pharmaceutical Analysis. ACS Omega, 9 (1): (1554–1561). [PMID:38222631]
18. Wei Yaru, Zhang Kaili, Cheng Tiexin, Zhou Guangdong. (2023) Characteristics and Mechanisms of Cr(VI) Removal from Aqueous Solution by FeSm/BC Composite. WATER AIR AND SOIL POLLUTION, 234 (2): (1-13). [PMID:]
19. Shengming Xu, Jing Xu, Linying Hu, Ye Liu, Lijun Ma. (2021) S-Scheme heterojunction based on the in situ coated core–shell NiCo2S4@WS2 photocatalyst was constructed for efficient photocatalytic hydrogen evolution. NEW JOURNAL OF CHEMISTRY, 46 (1): (57-69). [PMID:]

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N-Methylthiourea - 98%, high purity , CAS No.598-52-7