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N,N'-Bis(3-aminopropyl)-1,4-butanediamine Tetrahydrochloride - 10mM in Water, high purity , CAS No.306-67-2

  • 10mM in Water
Item Number
N423174
Grouped product items
SKUSizeAvailabilityPrice Qty
N423174-1ml
1ml
Available within 4-8 weeks(?)
Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience!
$74.90

Polyamine used for precipitation of DNA from low salt aqueous buffers.

Basic Description

SynonymsSpermine tetrahydrochloride|306-67-2|N,N'-Bis(3-aminopropyl)-1,4-butanediamine tetrahydrochloride|Gerontine tetrahydrochloride|Neuridine tetrahydrochloride|Musculamine tetrahydrochloride|N1,N1'-(Butane-1,4-diyl)bis(propane-1,3-diamine) tetrahydrochloride|
Specifications & Purity10mM in Water
Biochemical and Physiological MechanismsMixed NMDA agonist/antagonist at the polyamine site. Neuroprotective effects have been observed at high concentrations (1 mM), while neurotoxicity is observed at lower concentrations. It enhances agonist effectiveness at the strychnine-insensitive glycine
Storage TempStore at -80°C
Shipped InIce chest + Ice pads
Product Description

Mixed NMDA agonist/antagonist at the polyamine site. Neuroprotective effects have been observed at high concentrations (1 mM), while neurotoxicity is observed at lower concentrations. It enhances agonist effectiveness at the strychnine-insensitive glycine site. Plays a role in cellular proliferation and differentiation; inhibits neuronal nitric oxide synthase (nNOS). Mixed NMDA agonist/antagonist at the polyamine site. Plays a role in cellular proliferation and differentiation; inhibits neuronal nitric oxide synthase (nNOS).

Associated Targets

PMP22 Tbio Peripheral myelin protein 22 0 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

MAPT Tclin Microtubule-associated protein tau 0 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

Names and Identifiers

IUPAC Name N,N'-bis(3-aminopropyl)butane-1,4-diamine;tetrahydrochloride
INCHI InChI=1S/C10H26N4.4ClH/c11-5-3-9-13-7-1-2-8-14-10-4-6-12;;;;/h13-14H,1-12H2;4*1H
InChi Key XLDKUDAXZWHPFH-UHFFFAOYSA-N
Canonical SMILES C(CCNCCCN)CNCCCN.Cl.Cl.Cl.Cl
Isomeric SMILES C(CCNCCCN)CNCCCN.Cl.Cl.Cl.Cl
WGK Germany 3
RTECS EJ7230000
Alternate CAS 1255099-40-1
PubChem CID 9384
Molecular Weight 348.18
Reaxy-Rn 3911771

Certificates

Certificate of Analysis(COA)

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Chemical and Physical Properties

SensitivityHygroscopic
Melt Point(°C)315°C

Safety and Hazards(GHS)

Pictogram(s) GHS07
Signal Warning
Hazard Statements

H315:Causes skin irritation

H319:Causes serious eye irritation

H335:May cause respiratory irritation

Precautionary Statements

P261:Avoid breathing dust/fume/gas/mist/vapors/spray.

P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses if present and easy to do - continue rinsing.

P280:Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352:IF ON SKIN: wash with plenty of water.

P321:Specific treatment (see ... on this label).

P405:Store locked up.

P501:Dispose of contents/container to ...

P264:Wash hands [and …] thoroughly after handling.

P271:Use only outdoors or in a well-ventilated area.

P304+P340:IF INHALED: Remove person to fresh air and keep comfortable for breathing.

P403+P233:Store in a well-ventilated place. Keep container tightly closed.

P362+P364:Take off contaminated clothing and wash it before reuse.

P264+P265:Wash hands [and …] thoroughly after handling. Do not touch eyes.

P337+P317:If eye irritation persists: Get medical help.

P332+P317:If skin irritation occurs: Get medical help.

P319:Get medical help if you feel unwell.

WGK Germany 3
RTECS EJ7230000
Reaxy-Rn 3911771

Related Documents

Solution Calculators