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Synonyms | N,N-Dimethylformamide dimethyl acetal | 4637-24-5 | 1,1-dimethoxy-N,N-dimethylmethanamine | 1,1-Dimethoxytrimethylamine | Methanamine, 1,1-dimethoxy-N,N-dimethyl- | (dimethoxymethyl)dimethylamine | DMF Dimethyl acetal | DMFDMA | Dimethylformamide-dimethylacetal | Dimethylf |
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Specifications & Purity | 97% |
Storage Temp | Argon charged |
Shipped In | Normal |
Product Description | N,N-Dimethylformamide dimethyl acetal is a reagent for n-dimethylaminomethylene and methyl esters. It is used to catalyze the coupling of epoxides with carbon dioxide under solvent free conditions leading to cyclic carbonates. |
Pubchem Sid | 488185569 |
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Pubchem Sid Url | https://pubchem.ncbi.nlm.nih.gov/substance/488185569 |
IUPAC Name | 1,1-dimethoxy-N,N-dimethylmethanamine |
INCHI | InChI=1S/C5H13NO2/c1-6(2)5(7-3)8-4/h5H,1-4H3 |
InChi Key | ZSXGLVDWWRXATF-UHFFFAOYSA-N |
Canonical SMILES | CN(C)C(OC)OC |
Isomeric SMILES | CN(C)C(OC)OC |
WGK Germany | 2 |
PubChem CID | 78373 |
UN Number | 1993 |
Molecular Weight | 119.16 |
Beilstein | 506020 |
Reaxy-Rn | 506020 |
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Lot Number | Certificate Type | Date | Item |
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K2211739 | Certificate of Analysis | Aug 22, 2024 | D106288 |
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H2430599 | Certificate of Analysis | Aug 20, 2024 | D106288 |
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F2126075 | Certificate of Analysis | Mar 29, 2021 | D106288 |
Solubility | Miscible with most organic solvents. |
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Sensitivity | Moisture sensitive. |
Refractive Index | 1.3972 |
Flash Point(°F) | 42.8 °F |
Flash Point(°C) | 7℃ |
Boil Point(°C) | 104-108°C |
Melt Point(°C) | -85°C |
Pictogram(s) | GHS05, GHS07, GHS02 |
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Signal | Danger |
Hazard Statements | H315:Causes skin irritation H319:Causes serious eye irritation H335:May cause respiratory irritation H302:Harmful if swallowed H318:Causes serious eye damage H225:Highly Flammable liquid and vapor H317:May cause an allergic skin reaction H332:Harmful if inhaled |
Precautionary Statements | P261:Avoid breathing dust/fume/gas/mist/vapors/spray. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses if present and easy to do - continue rinsing. P280:Wear protective gloves/protective clothing/eye protection/face protection. P370+P378:In case of fire: Use ... to extinguish. P210:Keep away from heat, hot surface, sparks, open flames and other ignition sources. - No smoking. P302+P352:IF ON SKIN: wash with plenty of water. P321:Specific treatment (see ... on this label). P405:Store locked up. P501:Dispose of contents/container to ... P233:Keep container tightly closed. P240:Ground/bond container and receiving equipment. P264:Wash hands [and …] thoroughly after handling. P403+P235:Store in a well-ventilated place. Keep cool. P303+P361+P353:IF ON SKIN (or hair): Take off Immediately all contaminated clothing. Rinse SKIN with water [or shower]. P271:Use only outdoors or in a well-ventilated area. P241:Use explosion-proof [electrical/ventilating/lighting/.../] equipment. P270:Do not eat, drink or smoke when using this product. P304+P340:IF INHALED: Remove person to fresh air and keep comfortable for breathing. P403+P233:Store in a well-ventilated place. Keep container tightly closed. P272:Contaminated work clothing should not be allowed out of the workplace. P333+P313:IF SKIN irritation or rash occurs: Get medical advice/attention. P362+P364:Take off contaminated clothing and wash it before reuse. P330:Rinse mouth. P242:Use only non-sparking tools. P243:Take precautionary measures against static discharge. P264+P265:Wash hands [and …] thoroughly after handling. Do not touch eyes. P301+P317:IF SWALLOWED: Get medical help. P305+P354+P338:IF IN EYES: Immediately rinse with water for several minutes. Remove contact lenses if present and easy to do. Continue rinsing. P317:Get emergency medical help. P337+P317:If eye irritation persists: Get medical help. P332+P317:If skin irritation occurs: Get medical help. P319:Get medical help if you feel unwell. |
WGK Germany | 2 |
Reaxy-Rn | 506020 |
Starting at $69.90
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5. Toshiaki Sasada,Norio Sakai,Takeo Konakahara. (2008-07-30) Me3SiCl-promoted three-component coupling reaction of a functionalized enamine, an acetal, and an alkyne: an unprecedented approach to the synthesis of tetrasubstituted pyridines via a [3 + 2 + 1] intermolecular cyclization.. The Journal of organic chemistry, 73 ((17)): (6905-6908). [PMID:18661946] |
6. Jie Hu,Yali Zhang,Lili Dong,Zhe Wang,Lingfeng Chen,Dandan Liang,Dengjian Shi,Xiaoou Shan,Guang Liang. (2014-10-21) Design, Synthesis, and Biological Evaluation of Novel Quinazoline Derivatives as Anti-inflammatory Agents against Lipopolysaccharide-induced Acute Lung Injury in Rats.. Chemical biology & drug design, 85 ((6)): (672-684). [PMID:25327896] |
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8. Qingfen Zhang,Vicki H Wysocki,Patricia Y Scaraffia,Michael A Wells. (2005-06-01) Fragmentation pathway for glutamine identification: loss of 73 Da from dimethylformamidine glutamine isobutyl ester.. Journal of the American Society for Mass Spectrometry, 16 ((7)): (1192-1203). [PMID:15922620] |
9. C Freissinet,A Buch,R Sternberg,C Szopa,C Geffroy-Rodier,C Jelinek,M Stambouli. (2009-12-29) Search for evidence of life in space: analysis of enantiomeric organic molecules by N,N-dimethylformamide dimethylacetal derivative dependant Gas Chromatography-Mass Spectrometry.. Journal of chromatography. A, 1217 ((5)): (731-740). [PMID:20036768] |
10. Anirban Sarkar,Sudipta Raha Roy,Dinesh Kumar,Chetna Madaan,Santosh Rudrawar,Asit K Chakraborti. (2011-11-08) Lack of correlation between catalytic efficiency and basicity of amines during the reaction of aryl methyl ketones with DMF-DMA: an unprecedented supramolecular domino catalysis.. Organic & biomolecular chemistry, 10 ((2)): (281-286). [PMID:22057389] |
11. Brad S Lambert,Kevin L Shimkus,James D Fluckey,Steven E Riechman,Nicholas P Greene,Jessica M Cardin,Stephen F Crouse. (2014-11-27) Anabolic responses to acute and chronic resistance exercise are enhanced when combined with aquatic treadmill exercise.. American journal of physiology. Endocrinology and metabolism, 308 ((3)): (E192-E200). [PMID:25425002] |