N,N-Dimethylformamide Dimethyl Acetal - 97%, high purity , CAS No.4637-24-5

  • ≥97%
Item Number
D106288
Grouped product items
SKUSizeAvailabilityPrice Qty
D106288-25ml
25ml
In stock
$37.90
D106288-100ml
100ml
In stock
$96.90
D106288-500ml
500ml
In stock
$284.90

Basic Description

SynonymsN,N-Dimethylformamide dimethyl acetal | 4637-24-5 | 1,1-dimethoxy-N,N-dimethylmethanamine | 1,1-Dimethoxytrimethylamine | Methanamine, 1,1-dimethoxy-N,N-dimethyl- | (dimethoxymethyl)dimethylamine | DMF Dimethyl acetal | DMFDMA | Dimethylformamide-dimethylacetal | Dimethylf
Specifications & Purity97%
Storage TempArgon charged
Shipped InNormal
Product Description

N,N-Dimethylformamide dimethyl acetal is a reagent for n-dimethylaminomethylene and methyl esters. It is used to catalyze the coupling of epoxides with carbon dioxide under solvent free conditions leading to cyclic carbonates.
A reagent for n-dimethylaminomethylene and methyl esters;It may be used in methylation of heterocyclic compounds which contains SH, NH, OH groups such as benzimidazole, naphth[2,3-c]imidazole, imidazo[4,5-c]-pyridine, purine, pyridine, pyrimidine, pyridazine and s-triazolo[4,3-b]pyridazine. It was used as derivatizing agent in a study to determine cocaine and benzoyl ecgonine in urine using GC with on-column alkylation. Suitable for the derivatization of primary sulfonamides and trifluoroacetic acid. Used in the preparation of formamidine derivatives, which are synthetic intermediates. Used to catalyze the coupling of epoxides with carbon dioxide under solvent free conditions leading to cyclic carbonates.

Names and Identifiers

Pubchem Sid488185569
Pubchem Sid Urlhttps://pubchem.ncbi.nlm.nih.gov/substance/488185569
IUPAC Name 1,1-dimethoxy-N,N-dimethylmethanamine
INCHI InChI=1S/C5H13NO2/c1-6(2)5(7-3)8-4/h5H,1-4H3
InChi Key ZSXGLVDWWRXATF-UHFFFAOYSA-N
Canonical SMILES CN(C)C(OC)OC
Isomeric SMILES CN(C)C(OC)OC
WGK Germany 2
PubChem CID 78373
UN Number 1993
Molecular Weight 119.16
Beilstein 506020
Reaxy-Rn 506020

Certificates

Certificate of Analysis(COA)

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32 results found

Lot NumberCertificate TypeDateItem
K2211739Certificate of AnalysisAug 22, 2024 D106288
K2211643Certificate of AnalysisAug 22, 2024 D106288
H2430599Certificate of AnalysisAug 20, 2024 D106288
H2430597Certificate of AnalysisAug 20, 2024 D106288
G2417676Certificate of AnalysisApr 24, 2024 D106288
G2417337Certificate of AnalysisApr 24, 2024 D106288
G2417282Certificate of AnalysisApr 24, 2024 D106288
F2411322Certificate of AnalysisApr 24, 2024 D106288
C2202283Certificate of AnalysisDec 11, 2023 D106288
G2310658Certificate of AnalysisJun 14, 2023 D106288
G2310674Certificate of AnalysisJun 14, 2023 D106288
G2310677Certificate of AnalysisJun 14, 2023 D106288
G2310688Certificate of AnalysisJun 14, 2023 D106288
G2310694Certificate of AnalysisJun 14, 2023 D106288
G2310716Certificate of AnalysisJun 14, 2023 D106288
G2310721Certificate of AnalysisJun 14, 2023 D106288
A2408130Certificate of AnalysisJun 14, 2023 D106288
H2125111Certificate of AnalysisMay 15, 2023 D106288
G2107111Certificate of AnalysisApr 13, 2023 D106288
F2126074Certificate of AnalysisApr 11, 2023 D106288
F2126076Certificate of AnalysisApr 11, 2023 D106288
K2211746Certificate of AnalysisJul 25, 2022 D106288
K2211733Certificate of AnalysisJul 25, 2022 D106288
F23081021Certificate of AnalysisJul 25, 2022 D106288
D2313830Certificate of AnalysisJul 25, 2022 D106288
C23311627Certificate of AnalysisJul 25, 2022 D106288
B2322981Certificate of AnalysisJul 25, 2022 D106288
H2020098Certificate of AnalysisJun 17, 2022 D106288
H2020096Certificate of AnalysisJun 17, 2022 D106288
C23311621Certificate of AnalysisJan 22, 2022 D106288
C2202278Certificate of AnalysisJan 22, 2022 D106288
F2126075Certificate of AnalysisMar 29, 2021 D106288

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Chemical and Physical Properties

SolubilityMiscible with most organic solvents.
SensitivityMoisture sensitive.
Refractive Index1.3972
Flash Point(°F)42.8 °F
Flash Point(°C)7℃
Boil Point(°C)104-108°C
Melt Point(°C)-85°C

Safety and Hazards(GHS)

Pictogram(s) GHS05,   GHS07,   GHS02
Signal Danger
Hazard Statements

H315:Causes skin irritation

H319:Causes serious eye irritation

H335:May cause respiratory irritation

H302:Harmful if swallowed

H318:Causes serious eye damage

H225:Highly Flammable liquid and vapor

H317:May cause an allergic skin reaction

H332:Harmful if inhaled

Precautionary Statements

P261:Avoid breathing dust/fume/gas/mist/vapors/spray.

P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses if present and easy to do - continue rinsing.

P280:Wear protective gloves/protective clothing/eye protection/face protection.

P370+P378:In case of fire: Use ... to extinguish.

P210:Keep away from heat, hot surface, sparks, open flames and other ignition sources. - No smoking.

P302+P352:IF ON SKIN: wash with plenty of water.

P321:Specific treatment (see ... on this label).

P405:Store locked up.

P501:Dispose of contents/container to ...

P233:Keep container tightly closed.

P240:Ground/bond container and receiving equipment.

P264:Wash hands [and …] thoroughly after handling.

P403+P235:Store in a well-ventilated place. Keep cool.

P303+P361+P353:IF ON SKIN (or hair): Take off Immediately all contaminated clothing. Rinse SKIN with water [or shower].

P271:Use only outdoors or in a well-ventilated area.

P241:Use explosion-proof [electrical/ventilating/lighting/.../] equipment.

P270:Do not eat, drink or smoke when using this product.

P304+P340:IF INHALED: Remove person to fresh air and keep comfortable for breathing.

P403+P233:Store in a well-ventilated place. Keep container tightly closed.

P272:Contaminated work clothing should not be allowed out of the workplace.

P333+P313:IF SKIN irritation or rash occurs: Get medical advice/attention.

P362+P364:Take off contaminated clothing and wash it before reuse.

P330:Rinse mouth.

P242:Use only non-sparking tools.

P243:Take precautionary measures against static discharge.

P264+P265:Wash hands [and …] thoroughly after handling. Do not touch eyes.

P301+P317:IF SWALLOWED: Get medical help.

P305+P354+P338:IF IN EYES: Immediately rinse with water for several minutes. Remove contact lenses if present and easy to do. Continue rinsing.

P317:Get emergency medical help.

P337+P317:If eye irritation persists: Get medical help.

P332+P317:If skin irritation occurs: Get medical help.

P319:Get medical help if you feel unwell.

WGK Germany 2
Reaxy-Rn 506020

Related Documents

References

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2. C Rodier,C Laurent,C Szopa,R Sternberg,F Raulin.  (2002-07-12)  Chirality and the origin of life: in situ enantiomeric separation for future space missions..  Chirality,  14  ((6)): (527-532).  [PMID:12112349]
3. Wim Schepens,Dirk Van Haver,Maurits Vandewalle,Roger Bouillon,Annemieke Verstuyf,Pierre J De Clercq.  (2006-09-08)  Synthesis of spiro[4.5]decane CF-ring analogues of 1 alpha,25-dihydroxyvitamin D3..  Organic letters,  ((19)): (4247-4250).  [PMID:16956198]
4. Khadijah M Al-Zaydi,Rita M Borik.  (2007-10-26)  Microwave assisted condensation reactions of 2-aryl hydrazonopropanals with nucleophilic reagents and dimethyl acetylenedicarboxylate..  Molecules (Basel, Switzerland),  12  ((8)): (2061-2079).  [PMID:17960106]
5. Toshiaki Sasada,Norio Sakai,Takeo Konakahara.  (2008-07-30)  Me3SiCl-promoted three-component coupling reaction of a functionalized enamine, an acetal, and an alkyne: an unprecedented approach to the synthesis of tetrasubstituted pyridines via a [3 + 2 + 1] intermolecular cyclization..  The Journal of organic chemistry,  73  ((17)): (6905-6908).  [PMID:18661946]
6. Jie Hu,Yali Zhang,Lili Dong,Zhe Wang,Lingfeng Chen,Dandan Liang,Dengjian Shi,Xiaoou Shan,Guang Liang.  (2014-10-21)  Design, Synthesis, and Biological Evaluation of Novel Quinazoline Derivatives as Anti-inflammatory Agents against Lipopolysaccharide-induced Acute Lung Injury in Rats..  Chemical biology & drug design,  85  ((6)): (672-684).  [PMID:25327896]
7. R J Perchalski,B J Wilder.  (1980-01-01)  GLC analysis of carbamazepine..  Therapeutic drug monitoring,  ((3)): (289-289).  [PMID:7222183]
8. Qingfen Zhang,Vicki H Wysocki,Patricia Y Scaraffia,Michael A Wells.  (2005-06-01)  Fragmentation pathway for glutamine identification: loss of 73 Da from dimethylformamidine glutamine isobutyl ester..  Journal of the American Society for Mass Spectrometry,  16  ((7)): (1192-1203).  [PMID:15922620]
9. C Freissinet,A Buch,R Sternberg,C Szopa,C Geffroy-Rodier,C Jelinek,M Stambouli.  (2009-12-29)  Search for evidence of life in space: analysis of enantiomeric organic molecules by N,N-dimethylformamide dimethylacetal derivative dependant Gas Chromatography-Mass Spectrometry..  Journal of chromatography. A,  1217  ((5)): (731-740).  [PMID:20036768]
10. Anirban Sarkar,Sudipta Raha Roy,Dinesh Kumar,Chetna Madaan,Santosh Rudrawar,Asit K Chakraborti.  (2011-11-08)  Lack of correlation between catalytic efficiency and basicity of amines during the reaction of aryl methyl ketones with DMF-DMA: an unprecedented supramolecular domino catalysis..  Organic & biomolecular chemistry,  10  ((2)): (281-286).  [PMID:22057389]
11. Brad S Lambert,Kevin L Shimkus,James D Fluckey,Steven E Riechman,Nicholas P Greene,Jessica M Cardin,Stephen F Crouse.  (2014-11-27)  Anabolic responses to acute and chronic resistance exercise are enhanced when combined with aquatic treadmill exercise..  American journal of physiology. Endocrinology and metabolism,  308  ((3)): (E192-E200).  [PMID:25425002]

Solution Calculators