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N-Phenylanthranilic acid - Analytical Reagent,95%, high purity , CAS No.91-40-7, Channel blocker of ClC-2
Basic Description Synonyms N-phenylanthranilic acid|91-40-7|Fenamic acid|2-(Phenylamino)benzoic acid|2-Anilinobenzoic acid|Diphenylamine-2-carboxylic acid|Phenylanthranilic acid|Benzoic acid, 2-(phenylamino)-|2-Carboxydiphenylamine|o-Anilinobenzoic acid|N-Phenyl-o-aminobenzoic acid Specifications & Purity Moligand™, AR, ≥95% Shipped In Normal Grade AR, Moligand™ Action Type CHANNEL BLOCKER Mechanism of action Channel blocker of ClC-2 Product Description DPC is a potent, non-specific blocker of Cl- channel and chloride-bicarbonate exchange. DPC also inhibits CFTR (cystic fibrosis transmembrane regulator) ATPase activity.
Names and Identifiers IUPAC Name 2-anilinobenzoic acid INCHI InChI=1S/C13H11NO2/c15-13(16)11-8-4-5-9-12(11)14-10-6-2-1-3-7-10/h1-9,14H,(H,15,16) InChi Key ZWJINEZUASEZBH-UHFFFAOYSA-N Canonical SMILES C1=CC=C(C=C1)NC2=CC=CC=C2C(=O)O Isomeric SMILES C1=CC=C(C=C1)NC2=CC=CC=C2C(=O)O WGK Germany 3 RTECS CB3730000 PubChem CID 4386 Molecular Weight 213.23 Beilstein 1456607 Reaxy-Rn 1456607
Chemical and Physical Properties Solubility Soluble in ethanol, DMSO (50 mg/ml), hot alcohol, and methanol. Insoluble in water Melt Point(°C) 185-188°C
Safety and Hazards(GHS) Pictogram(s) GHS07 Signal Warning Hazard Statements H315: Causes skin irritation
H319: Causes serious eye irritation
H335: May cause respiratory irritation
Precautionary Statements P261: Avoid breathing dust/fume/gas/mist/vapors/spray.
P305+P351+P338: IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses if present and easy to do - continue rinsing.
P280: Wear protective gloves/protective clothing/eye protection/face protection.
P302+P352: IF ON SKIN: wash with plenty of water.
P321: Specific treatment (see ... on this label).
P405: Store locked up.
P501: Dispose of contents/container to ...
P264: Wash hands [and …] thoroughly after handling.
P271: Use only outdoors or in a well-ventilated area.
P304+P340: IF INHALED: Remove person to fresh air and keep comfortable for breathing.
P403+P233: Store in a well-ventilated place. Keep container tightly closed.
P362+P364: Take off contaminated clothing and wash it before reuse.
P264+P265: Wash hands [and …] thoroughly after handling. Do not touch eyes.
P337+P317: If eye irritation persists: Get medical help.
P332+P317: If skin irritation occurs: Get medical help.
P319: Get medical help if you feel unwell.
WGK Germany 3 RTECS CB3730000 Reaxy-Rn 1456607 Merck Index 7273
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