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N-Isobutyryl-L-cysteine - ≥97%, high purity , CAS No.124529-02-8

  • ≥97%
Item Number
N337613
Grouped product items
SKUSizeAvailabilityPrice Qty
N337613-250mg
250mg
4
$80.90
N337613-1g
1g
1
$267.90

an agent for chiral derivitization

View related series
Amine (116) Amino acids (127)

Basic Description

Synonyms(2R)-2-(2-methylpropanamido)-3-sulfanylpropanoic acid | N-(2-Methylpropionyl)-L-cysteine | (2R)-2-(2-methylpropanoylamino)-3-sulfanylpropanoic acid | N-Isobutyryl-L-cysteine | (R)-2-Isobutyramido-3-mercaptopropanoic acid | L-Cysteine, N-(2-methyl-1-oxopro
Specifications & Purity≥97%
Storage TempStore at 2-8°C,Argon charged
Shipped InWet ice
Product Description

N-Isobutyryl-L-cysteine is a thiol compound, which distinguishes chirality in assays involving amino acids with OPA. N-Isobutyryl-L-cysteine is employed along with gold particles on a monolayer surface to separate single stranded DNA, via the interaction between the dipole moment of N-Isobutyryl-L-cysteine and the negative charge of single stranded DNA. These studies determined that N-Isobutyryl-L-cysteine is an essential tool along with gold nanoparticles in vibrational circular dichroism (VCD) and circular dichroism (CD) spectroscopy. Furthermore, the L isomer is more effective in adsorption of relaxed DNA compared to the D form which causes DNA to supercoil and results in a weaker binding strength.

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Mechanisms of Action

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Mechanism of ActionAction Typetarget IDTarget NameTarget TypeTarget OrganismBinding Site NameReferences

Names and Identifiers

Pubchem Sid488187806
Pubchem Sid Urlhttps://pubchem.ncbi.nlm.nih.gov/substance/488187806
IUPAC Name (2R)-2-(2-methylpropanoylamino)-3-sulfanylpropanoic acid
INCHI InChI=1S/C7H13NO3S/c1-4(2)6(9)8-5(3-12)7(10)11/h4-5,12H,3H2,1-2H3,(H,8,9)(H,10,11)/t5-/m0/s1
InChi Key BWBQXMAXLAHHTK-YFKPBYRVSA-N
Canonical SMILES CC(C)C(=O)NC(CS)C(=O)O
Isomeric SMILES CC(C)C(=O)N[C@@H](CS)C(=O)O
PubChem CID 130211
Molecular Weight 191.25

Certificates(CoA,COO,BSE/TSE and Analysis Chart)

C of A & Other Certificates(BSE/TSE, COO):
Analytical Chart:

Find and download the COA for your product by matching the lot number on the packaging.

9 results found

Lot NumberCertificate TypeDateItem
H2408386Certificate of AnalysisJun 17, 2024 N337613
H2408387Certificate of AnalysisJun 17, 2024 N337613
E2305616Certificate of AnalysisApr 15, 2023 N337613
E2305637Certificate of AnalysisApr 15, 2023 N337613
E2305638Certificate of AnalysisApr 15, 2023 N337613
E2305671Certificate of AnalysisApr 15, 2023 N337613
A2305137Certificate of AnalysisSep 23, 2022 N337613
L2213405Certificate of AnalysisSep 23, 2022 N337613
L2213484Certificate of AnalysisSep 23, 2022 N337613

Chemical and Physical Properties

SensitivityMoisture sensitive;Air sensitive
Melt Point(°C)97-101° C
Molecular Weight191.250 g/mol
XLogP30.500
Hydrogen Bond Donor Count3
Hydrogen Bond Acceptor Count4
Rotatable Bond Count4
Exact Mass191.062 Da
Monoisotopic Mass191.062 Da
Topological Polar Surface Area67.400 Ų
Heavy Atom Count12
Formal Charge0
Complexity181.000
Isotope Atom Count0
Defined Atom Stereocenter Count1
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
The total count of all stereochemical bonds0
Covalently-Bonded Unit Count1

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