Nα-p-Tosyl-L-arginine methyl ester hydrochloride - 98%, high purity , CAS No.1784-03-8

  • ≥98%
Item Number
T105948
Grouped product items
SKUSizeAvailabilityPrice Qty
T105948-1g
1g
In stock
$22.90
T105948-5g
5g
In stock
$102.90
T105948-25g
25g
In stock
$176.90
T105948-100g
100g
In stock
$636.90

Competitive ubiquitin ligase APC/C inhibitor.

Basic Description

SynonymsCCG-268391 | methyl tosyl-L-argininate hydrochloride | T0330 | N2-[(4-Methylphenyl)sulfonyl]-L-arginine methyl ester hydrochloride | D92326 | N-a-Tosyl-L-arginine methyl ester HCl | (S)-Methyl 5-guanidino-2-(4-methylphenylsulfonamido)pentanoate hydrochlor
Specifications & Purity≥98%
Biochemical and Physiological MechanismsNα-p-Tosyl-L-arginine methyl ester (TAME) binds to anaphase-promoting complex (APC) and prevents its activation by Cdc20 and Cdh1.Competitive ubiquitin ligase anaphase-promoting complex/cyclosome (APC/C) inhibitor. Promotes Cdc20 autoubiquitination by eje
Storage TempStore at -20°C
Shipped InIce chest + Ice pads
NoteWherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour. Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
Product Description

Substrate for trypsin, thrombin, plasmin,and other proteases.

Names and Identifiers

Pubchem Sid488192192
Pubchem Sid Urlhttps://pubchem.ncbi.nlm.nih.gov/substance/488192192
IUPAC Name methyl (2S)-5-(diaminomethylideneamino)-2-[(4-methylphenyl)sulfonylamino]pentanoate;hydrochloride
INCHI InChI=1S/C14H22N4O4S.ClH/c1-10-5-7-11(8-6-10)23(20,21)18-12(13(19)22-2)4-3-9-17-14(15)16;/h5-8,12,18H,3-4,9H2,1-2H3,(H4,15,16,17);1H/t12-;/m0./s1
InChi Key JIQFFACVQXXHMY-YDALLXLXSA-N
Canonical SMILES CC1=CC=C(C=C1)S(=O)(=O)NC(CCCN=C(N)N)C(=O)OC.Cl
Isomeric SMILES CC1=CC=C(C=C1)S(=O)(=O)N[C@@H](CCCN=C(N)N)C(=O)OC.Cl
WGK Germany 3
PubChem CID 2723792
Molecular Weight 378.87
Beilstein 3922357
Reaxy-Rn 10499395

Certificates

Certificate of Analysis(COA)

Enter Lot Number to search for COA:

Find and download the COA for your product by matching the lot number on the packaging.

11 results found

Lot NumberCertificate TypeDateItem
G1604030Certificate of AnalysisMar 13, 2024 T105948
B23021134Certificate of AnalysisOct 25, 2022 T105948
B2302718Certificate of AnalysisOct 25, 2022 T105948
B2302757Certificate of AnalysisOct 25, 2022 T105948
B2302767Certificate of AnalysisOct 25, 2022 T105948
B2302934Certificate of AnalysisOct 25, 2022 T105948
B2303563Certificate of AnalysisOct 25, 2022 T105948
B2303570Certificate of AnalysisOct 25, 2022 T105948
B2303571Certificate of AnalysisOct 25, 2022 T105948
I2402439Certificate of AnalysisOct 26, 2021 T105948
J2213139Certificate of AnalysisOct 26, 2021 T105948

Show more⌵

Chemical and Physical Properties

Specific Rotation[α]-14 ° (C=4, H2O)
Melt Point(°C)146-149°C

Safety and Hazards(GHS)

WGK Germany 3
Reaxy-Rn 10499395

Related Documents

Citations of This Product

1. Hanfei Ye, Wenwen Yu.  (2024)  Different influences of dietary fiber from various sources on the in vitro digestibility of casein as uncovered by the study of protein-dietary fiber interactions.  FOOD RESEARCH INTERNATIONAL,  176  (113845).  [PMID:38163735] [10.1016/j.foodres.2023.113845]

References

1. Hanfei Ye, Wenwen Yu.  (2024)  Different influences of dietary fiber from various sources on the in vitro digestibility of casein as uncovered by the study of protein-dietary fiber interactions.  FOOD RESEARCH INTERNATIONAL,  176  (113845).  [PMID:38163735] [10.1016/j.foodres.2023.113845]

Solution Calculators