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Basic Description
| Specifications & Purity | sufficient for 100colorimetrictests |
|---|---|
| Storage Temp | Store at -80°C |
| Shipped In | Ice chest + Ice pads |
| Product Description | Nicotinamide adenine dinucleotide phosphate (NADP) is an enzymatic cofactor involved in many redox reactions where it cycles between the reduced (NADPH) and oxidized (NADP) forms. NADP is also involved in biosynthetic reactions such as lipid and nucleic acid synthesis where it functions as a reducing agent. The oxidative branch of the Pentose Phosphate Pathway (PPP) is the major source of NADPH produced in animal cells.NADP/NADPH (nicotinamide adenine dinucleotide phosphate) Quantitation Kit has been used for quantification of NADP/NADPH. It has been used to quantify NAD(P)H in order to determine SHMT2 (serine hydroxymethyltransferase 2) specific enzyme activity.Suitability: Suitable for the detection of NADP, NADPH and their ratio in a variety of biological samples including cell and tissue lysatesPrinciple: The NADP/NADPH Quantification Kit provides a convenient tool for sensitive detection of the intracellular nucleotides, NADP (nicotinamide adenine dinucleotide phosphate) and NADPH, and their ratio. There is no requirement to purify NADP/NADPH from samples. This assay is specific for NADP and NADPH and does not detect NAD or NADH. NADPt (NADP and NADPH) or NADPH are quantified in a colorimetric assay (450 nm). |
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References
| 1. Jade Mims,Nidhi Bansal,Manish S Bharadwaj,Xiaofei Chen,Anthony J Molina,Allen W Tsang,Cristina M Furdui. (2015-03-05) Energy metabolism in a matched model of radiation resistance for head and neck squamous cell cancer.. Radiation research, 183 ((3)): (291-304). [PMID:25738895] |
| 2. Chao Wang,Desong Tang,Yong-Gui Gao,Lian-Hui Zhang. (2016-01-13) Succinic Semialdehyde Promotes Prosurvival Capability of Agrobacterium tumefaciens.. Journal of bacteriology, 198 ((6)): (930-940). [PMID:26755630] |
| 3. Gayle M Gordillo,Ayan Biswas,Savita Khanna,James M Spieldenner,Xueliang Pan,Chandan K Sen. (2016-03-11) Multidrug Resistance-associated Protein-1 (MRP-1)-dependent Glutathione Disulfide (GSSG) Efflux as a Critical Survival Factor for Oxidant-enriched Tumorigenic Endothelial Cells.. The Journal of biological chemistry, 291 ((19)): (10089-10103). [PMID:26961872] |
| 4. May Al-Maghrebi,Waleed M Renno. (2016-07-22) Altered expression profile of glycolytic enzymes during testicular ischemia reperfusion injury is associated with the p53/TIGAR pathway: effect of fructose 1,6-diphosphate.. PeerJ, 4 (e2195-e2195). [PMID:27441124] |
| 5. Anders E Berglund,Kristen E N Scott,Weimin Li,Chunying Yang,Mario R Fernandez,Franz X Schaub,John L Cleveland,Robert J Rounbehler. (2016-11-09) Tristetraprolin disables prostate cancer maintenance by impairing proliferation and metabolic function.. Oncotarget, 7 ((50)): (83462-83475). [PMID:27825143] |
| 6. Raju V S Rajala,Ammaji Rajala,Christopher Kooker,Yuhong Wang,Robert E Anderson. (2016-11-25) The Warburg Effect Mediator Pyruvate Kinase M2 Expression and Regulation in the Retina.. Scientific reports, 6 (37727-37727). [PMID:27883057] |
| 7. Shanshan Sun,Fangyuan Hu,Jihong Wu,Shenghai Zhang. (2017-01-23) Cannabidiol attenuates OGD/R-induced damage by enhancing mitochondrial bioenergetics and modulating glucose metabolism via pentose-phosphate pathway in hippocampal neurons.. Redox biology, 11 (577-585). [PMID:28110213] |
| 8. Xin Yang,Zhe Wang,Xin Li,Boya Liu,Minghui Liu,Lu Liu,Shuaiyi Chen,Mengmeng Ren,Yankun Wang,Miao Yu,Bo Wang,Junhua Zou,Wei-Guo Zhu,Yuxin Yin,Wei Gu,Jianyuan Luo. (2017-11-29) SHMT2 Desuccinylation by SIRT5 Drives Cancer Cell Proliferation.. Cancer research, 78 ((2)): (372-386). [PMID:29180469] |
| 9. Andreas Carstensen,Andrei Herdean,Sidsel Birkelund Schmidt,Anurag Sharma,Cornelia Spetea,Mathias Pribil,Søren Husted. (2018-03-16) The Impacts of Phosphorus Deficiency on the Photosynthetic Electron Transport Chain.. Plant physiology, 177 ((1)): (271-284). [PMID:29540590] |
| 10. Zaijun Ma,Hui Wang,Yuping Cai,Han Wang,Kongyan Niu,Xiaofen Wu,Huanhuan Ma,Yun Yang,Wenhua Tong,Feng Liu,Zhandong Liu,Yaoyang Zhang,Rui Liu,Zheng-Jiang Zhu,Nan Liu. (2018-05-29) Epigenetic drift of H3K27me3 in aging links glycolysis to healthy longevity in Drosophila.. eLife, 7 [PMID:29809154] |
| 11. Xiaolong Zhang,Yanfeng Liu,Long Liu,Miao Wang,Jianghua Li,Guocheng Du,Jian Chen. (2018-06-14) Modular pathway engineering of key carbon-precursor supply-pathways for improved N-acetylneuraminic acid production in Bacillus subtilis.. Biotechnology and bioengineering, 115 ((9)): (2217-2231). [PMID:29896807] |
| 12. Cody J Champion,Jiannong Xu. (2018-08-31) Redox state affects fecundity and insecticide susceptibility in Anopheles gambiae.. Scientific reports, 8 ((1)): (13054-13054). [PMID:30158658] |
| 13. Marina Musa,Matea Perić,Peter Bou Dib,Sandra Sobočanec,Ana Šarić,Anita Lovrić,Marina Rudan,Andrea Nikolić,Ira Milosević,Kristian Vlahoviček,Nuno Raimundo,Anita Kriško. (2018-09-19) Heat-induced longevity in budding yeast requires respiratory metabolism and glutathione recycling.. Aging, 10 ((9)): (2407-2427). [PMID:30227387] |
| 14. Oleg Vetrovoy,Kseniia Sarieva,Olga Galkina,Natalia Eschenko,Andrey Lyanguzov,Tatjana Gluschenko,Ekaterina Tyulkova,Elena Rybnikova. (2018-11-19) Neuroprotective Mechanism of Hypoxic Post-conditioning Involves HIF1-Associated Regulation of the Pentose Phosphate Pathway in Rat Brain.. Neurochemical research, 44 ((6)): (1425-1436). [PMID:30448928] |
| 15. Matthew Wortham,Jacqueline R Benthuysen,Martina Wallace,Jeffrey N Savas,Francesca Mulas,Ajit S Divakaruni,Fenfen Liu,Verena Albert,Brandon L Taylor,Yinghui Sui,Enrique Saez,Anne N Murphy,John R Yates,Christian M Metallo,Maike Sander. (2018-12-06) Integrated In\xa0Vivo Quantitative Proteomics and Nutrient Tracing Reveals Age-Related Metabolic Rewiring of Pancreatic β Cell Function.. Cell reports, 25 ((10)): (2904-2918). [PMID:30517875] |
| 16. Ji Heon Noh,Kyoung Mi Kim,Poonam R Pandey,Nicole Noren Hooten,Rachel Munk,Gautam Kundu,Supriyo De,Jennifer L Martindale,Xiaoling Yang,Michele K Evans,Kotb Abdelmohsen,Myriam Gorospe. (2019-02-13) Loss of RNA-binding protein GRSF1 activates mTOR to elicit a proinflammatory transcriptional program.. Nucleic acids research, 47 ((5)): (2472-2486). [PMID:30753671] |
| 17. Gerta Hoxhaj,Issam Ben-Sahra,Sophie E Lockwood,Rebecca C Timson,Vanessa Byles,Graham T Henning,Peng Gao,Laura M Selfors,John M Asara,Brendan D Manning. (2019-03-09) Direct stimulation of NADP+ synthesis through Akt-mediated phosphorylation of NAD kinase.. Science (New York, N.Y.), 363 ((6431)): (1088-1092). [PMID:30846598] |
| 18. Chun-Mei Hu,Sui-Chih Tien,Ping-Kun Hsieh,Yung-Ming Jeng,Ming-Chu Chang,Yu-Ting Chang,Yi-Ju Chen,Yu-Ju Chen,Eva Y-H P Lee,Wen-Hwa Lee. (2019-03-12) High Glucose Triggers Nucleotide Imbalance through O-GlcNAcylation of Key Enzymes and Induces KRAS Mutation in Pancreatic Cells.. Cell metabolism, 29 ((6)): (1334-1349). [PMID:30853214] |
| 19. Jinrong Zhu,Geyan Wu,Libing Song,Lixue Cao,Zhanyao Tan,Miaoling Tang,Ziwen Li,Dongni Shi,Shuxia Zhang,Jun Li. (2019-05-03) NKX2-8 deletion-induced reprogramming of fatty acid metabolism confers chemoresistance in epithelial ovarian cancer.. EBioMedicine, 43 (238-252). [PMID:31047858] |
| 20. Tanakarn Monshupanee,Chayanee Chairattanawat,Aran Incharoensakdi. (2019-06-05) Disruption of cyanobacterial γ-aminobutyric acid shunt pathway reduces metabolites levels in tricarboxylic acid cycle, but enhances pyruvate and poly(3-hydroxybutyrate) accumulation.. Scientific reports, 9 ((1)): (8184-8184). [PMID:31160681] |
| 21. P P Akalin,Y Ergün,N Başpinar,G Doğruer,A Küçükgül,Z Cantekin,M İşgör,M Saribay,E Koldaş,A Baştan,S Salar,S Pehlivanlar. (2019-07-04) Glucose-6-phosphate dehydrogenase, glutathione peroxidase, total glutatione and reduced nicotinamide adenine dinucleotide phosphate in milk cells of subclinical mastitic cows.. Polish journal of veterinary sciences, 22 ((2)): (271-278). [PMID:31269353] |
| 22. Rajendran Velmurugan,Aran Incharoensakdi. (2019-07-06) Metal Oxide Mediated Extracellular NADPH Regeneration Improves Ethanol Production by Engineered Synechocystis sp. PCC 6803.. Frontiers in bioengineering and biotechnology, 7 (148-148). [PMID:31275934] |
| 23. Chuanchuan Lu,Yanfeng Liu,Jianghua Li,Long Liu,Guocheng Du. (2020-01-03) Engineering of Biosynthesis Pathway and NADPH Supply for Improved L-5-Methyltetrahydrofolate Production by Lactococcus lactis.. Journal of microbiology and biotechnology, 31 ((1)): (154-162). [PMID:31893598] |
| 24. Kateryna Shostak,Zheshen Jiang,Benoit Charloteaux,Alice Mayer,Yvette Habraken,Lars Tharun,Sebastian Klein,Xinyi Xu,Hong Quan Duong,Andrii Vislovukh,Pierre Close,Alexandra Florin,Florian Rambow,Jean-Christophe Marine,Reinhard Büttner,Alain Chariot. (2020-03-11) The X-linked trichothiodystrophy-causing gene RNF113A links the spliceosome to cell survival upon DNA damage.. Nature communications, 11 ((1)): (1270-1270). [PMID:32152280] |
| 25. Yang, et al.. (2020) Effectiveness and mechanism study of glutamine on alleviating hypermetabolism in burned rats.. Nutrition, (110934-110934). [PMID:32847775] |
| 26. Wonjae Seong,Gui Hwan Han,Hyun Seung Lim,Ji In Baek,Soo-Jung Kim,Donghyuk Kim,Seong Keun Kim,Hyewon Lee,Haseong Kim,Seung-Goo Lee,Dae-Hee Lee. (2020-09-16) Adaptive laboratory evolution of Escherichia coli lacking cellular byproduct formation for enhanced acetate utilization through compensatory ATP consumption.. Metabolic engineering, 62 (249-259). [PMID:32931907] |
| 27. Ling Guo,Chunhong Cui,Jiaxin Wang,Jifan Yuan,Qingyang Yang,Ping Zhang,Wen Su,Ruolu Bao,Jingchao Ran,Chuanyue Wu. (2020-10-03) PINCH-1 regulates mitochondrial dynamics to promote proline synthesis and tumor growth.. Nature communications, 11 ((1)): (4913-4913). [PMID:33004813] |
| 28. Thanh H Nguyen,Prasantha L Vemu,Gregory E Hoy,Salah Boudjadi,Bishwanath Chatterjee,Jack F Shern,Javed Khan,Wenyue Sun,Frederic G Barr. (2021-06-25) Serine hydroxymethyltransferase 2 expression promotes tumorigenesis in rhabdomyosarcoma with 12q13-q14 amplification.. The Journal of clinical investigation, 131 ((15)): [PMID:34166228] |
| 29. Hao Yang,Sha Xie,Beibei Liang,Qiqi Tang,Huanchen Liu,Dongliang Wang,Gang Huang. (2021-07-09) Exosomal IDH1 increases the resistance of colorectal cancer cells to 5-Fluorouracil.. Journal of Cancer, 12 ((16)): (4862-4872). [PMID:34234856] |
| 30. Diéssica Padilha Dalenogare,Camila Ritter,Fernando Roberto Antunes Bellinaso,Sabrina Qader Kudsi,Gabriele Cheiran Pereira,Maria Fernanda Pessano Fialho,Débora Denardin Lückemeyer,Caren Tatiane de David Antoniazzi,Lorenzo Landini,Juliano Ferreira,Guilherme Vargas Bochi,Sara Marchesan Oliveira,Francesco De Logu,Romina Nassini,Pierangelo Geppetti,Gabriela Trevisan. (2021-08-29) Periorbital Nociception in a Progressive Multiple Sclerosis Mouse Model Is Dependent on TRPA1 Channel Activation.. Pharmaceuticals (Basel, Switzerland), 14 ((8)): [PMID:34451927] |
| 31. Jennifer L Szczytkowski,Donald T Lysle. (2008-11-01) Conditioned effects of heroin on proinflammatory mediators require the basolateral amygdala.. The European journal of neuroscience, 28 ((9)): (1867-1876). [PMID:18973600] |
| 32. Enrico Desideri,Rolando Vegliante,Simone Cardaci,Ridvan Nepravishta,Maurizio Paci,Maria Rosa Ciriolo. (2014-07-22) MAPK14/p38α-dependent modulation of glucose metabolism affects ROS levels and autophagy during starvation.. Autophagy, 10 ((9)): (1652-1665). [PMID:25046111] |
| 33. Guo-Qing Chen,Cheng-Fang Tang,Xiao-Ke Shi,Cheng-Yuan Lin,Sarwat Fatima,Xiao-Hua Pan,Da-Jian Yang,Ge Zhang,Ai-Ping Lu,Shu-Hai Lin,Zhao-Xiang Bian. (2015-07-15) Halofuginone inhibits colorectal cancer growth through suppression of Akt/mTORC1 signaling and glucose metabolism.. Oncotarget, 6 ((27)): (24148-24162). [PMID:26160839] |
| 34. Luigi Mele,Francesca Paino,Federica Papaccio,Tarik Regad,David Boocock,Paola Stiuso,Angela Lombardi,Davide Liccardo,Gabriella Aquino,Antonio Barbieri,Claudio Arra,Clare Coveney,Marcella La Noce,Gianpaolo Papaccio,Michele Caraglia,Virginia Tirino,Vincenzo Desiderio. (2018-05-16) A new inhibitor of glucose-6-phosphate dehydrogenase blocks pentose phosphate pathway and suppresses malignant proliferation and metastasis in vivo.. Cell death & disease, 9 ((5)): (572-572). [PMID:29760380] |
| 35. Inge Grondman,Rob J W Arts,Rebecca M Koch,Guus P Leijte,Jelle Gerretsen,Niklas Bruse,Rosalie W M Kempkes,Rob Ter Horst,Matthijs Kox,Peter Pickkers,Mihai G Netea,Mark S Gresnigt. (2019-06-07) Frontline Science: Endotoxin-induced immunotolerance is associated with loss of monocyte metabolic plasticity and reduction of oxidative burst.. Journal of leukocyte biology, 106 ((1)): (11-25). [PMID:31169935] |
| 36. Wei Zeng,Zeting Xing,Meiyun Tan,Yanwen Wu,Chunyuan Zhang. (2021-03-23) Propofol regulates activated macrophages metabolism through inhibition of ROS-mediated GLUT1 expression.. Inflammation research : official journal of the European Histamine Research Society ... [et al.], 70 ((4)): (473-481). [PMID:33751130] |