| SKU | Size | Availability | Price | Qty |
|---|---|---|---|---|
| N408054-1ml | 1ml | Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding. | $173.90 |
β-lactamase Inhibitors
| Specifications & Purity | 10mM in DMSO |
|---|---|
| Storage Temp | Store at -80°C |
| Shipped In | Ice chest + Ice pads |
| Product Description | Information Nafcillin Sodium Nafcillin sodium (CL 8491) reversibly inhibits β-lactamase with K d of 33 mM. Nafcillin sodium inactivates β-lactamase through forming a covalent acyl-enzyme intermediate with β-lactamase via Ser-70. At concentrations above 80 mM, Nafcillin displays complete inhibition of β-lactamase within 200 s. Upon removal of the excess Nafcillin, the inhibited enzyme can be re-activated completely, with a rate constant of 2×10-3/s (25 ℃). Nafcillin sodium is activity against penicillin-resistant staphylococci. The minimal concentration necessary for antistaphylococcic activity in vitro ranges from 0.2 μg/mL to 2 μg/mL. In vivo
cell lines： Concentrations： Incubation Time： Powder Purity:≥99% |
| Canonical SMILES | O.CCOC1=C(C(=O)NC2C3SC(C)(C)C(N3C2=O)C(=O)O[Na])C4=C(C=CC=C4)C=C1 |
|---|---|
| Molecular Weight | 454.47 |
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