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Naphmethonium dibromide , CAS No.505059-27-8

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Naphmethonium dibromide , CAS No.505059-27-8

CAS#: 505059-27-8
Formula: C₃₈H₅₀Br₂N₄O₄
Molecular Weight: 786.6

Item Number

N357439

Grouped product items
SKU	Size	Availability	Price	Qty
N357439-5mg	5mg	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$209.90

Discover Naphmethonium dibromide by Aladdin Scientific in for only $209.90. Available - in Ligands at Aladdin Scientific. a potent allosteric modulator of muscarinic receptors Tags: .

Basic Description

Storage Temp	Store at 2-8°C
Shipped In	Wet ice
Product Description	Naphmethonium dibromide is a very potent allosteric modulator of muscarinic receptors, selective for M2-receptors. Retards the dissociation of the antagonist N-methylscopolamine and exhibits positive cooperativity, i.e. shows higher affinity for occupied receptors compared to free receptors. Naphmethonium dibromide's affinity for the free receptor is about 100-fold higher than with W84. pK\|A\|=8.29, p(αK\|A\|)=8.66, pEC\|50,diss\|=8.36.

Names and Identifiers

Canonical SMILES	O=C1c2ccccc2C(=O)N1CCC[N+](C)(C)CCCCCC[N+](C)(C)CC(C)(C)Cn1c(=O)c2cccc3cccc (c1=O)c23
Molecular Weight	786.6

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Chemical and Physical Properties

Solubility	Soluble in DMSO, water or aqueous buffer.

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