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Naproxen - >99.0%, high purity , CAS No.22204-53-1, Inhibitor of COX-1;Inhibitor of COX-2
Basic Description
| Synonyms | NAPROXEN|22204-53-1|(S)-Naproxen|Naprosyn|(+)-Naproxen|Naproxene|Equiproxen|(S)-2-(6-methoxynaphthalen-2-yl)propanoic acid|(S)-(+)-Naproxen|d-Naproxen|Ec-Naprosyn|(S)-(+)-2-(6-Methoxy-2-naphthyl)propionic acid|Aleve|Laraflex|Naprosyne|Naproxeno|Naproxenum |
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| Specifications & Purity | Moligand™, ≥99% |
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| Biochemical and Physiological Mechanisms | 非选择性环加氧酶(COX-1 和 COX-2)抑制剂。 |
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| Shipped In | Normal |
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| Grade | Moligand™ |
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| Action Type | INHIBITOR |
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| Mechanism of action | Inhibitor of COX-1;Inhibitor of COX-2 |
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| Product Description | Application：
(S)-(+)-6-Methoxy-α-methyl-2-naphthaleneacetic acid can be used as a chiral ligand in the synthesis of organotin (IV) carboxylate metal complexes. |
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Names and Identifiers
| IUPAC Name | (2S)-2-(6-methoxynaphthalen-2-yl)propanoic acid |
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| INCHI | InChI=1S/C14H14O3/c1-9(14(15)16)10-3-4-12-8-13(17-2)6-5-11(12)7-10/h3-9H,1-2H3,(H,15,16)/t9-/m0/s1 |
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| InChi Key | CMWTZPSULFXXJA-VIFPVBQESA-N |
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| Canonical SMILES | CC(C1=CC2=C(C=C1)C=C(C=C2)OC)C(=O)O |
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| Isomeric SMILES | C[C@@H](C1=CC2=C(C=C1)C=C(C=C2)OC)C(=O)O |
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| WGK Germany | 3 |
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| RTECS | UF5275000 |
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| PubChem CID | 156391 |
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| UN Number | 2811 |
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| Packing Group | III |
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| Molecular Weight | 230.26 |
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| Beilstein | 3591070 |
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| Reaxy-Rn | 3591067 |
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Chemical and Physical Properties
| Solubility | Insoluble in water. |
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| Sensitivity | light sensitive |
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| Specific Rotation[α] | 67.5° (C=1,CHCl3) |
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| Melt Point(°C) | 155 °C |
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Safety and Hazards(GHS)
| Pictogram(s) | GHS06, GHS08 |
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| Signal | Danger |
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| Hazard Statements | H315:Causes skin irritation H319:Causes serious eye irritation H301:Toxic if swallowed H317:May cause an allergic skin reaction H361:Suspected of damaging fertility or the unborn child |
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| Precautionary Statements | P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses if present and easy to do - continue rinsing. P280:Wear protective gloves/protective clothing/eye protection/face protection. P301+P310:IF SWALLOWED: Immediately call a POISON CENTER/doctor/... P302+P352:IF ON SKIN: wash with plenty of water. P405:Store locked up. P501:Dispose of contents/container to ... P264:Wash hands [and …] thoroughly after handling. P201:Obtain special instructions before use. P308+P313:IF exposed or concerned: Get medical advice/attention. P270:Do not eat, drink or smoke when using this product. P337+P313:IF eye irritation persists: Get medical advice/attention. P362+P364:Take off contaminated clothing and wash it before reuse. P332+P313:IF SKIN irritation occurs: Get medical advice/attention. P202:Do not handle until all safety precautions have been read and understood. P330:Rinse mouth. |
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| WGK Germany | 3 |
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| RTECS | UF5275000 |
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| Reaxy-Rn | 3591067 |
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| Class | 6.1 |
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| Merck Index | 6417 |
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