Skip to the beginning of the images gallery

Naringenin - natural (US), 98%, high purity , CAS No.67604-48-2, Agonist of TAS2R39;Channel blocker of TRPM3

from natural
Moligand™
≥98%

CAS#: 67604-48-2
Formula: C₁₅H₁₂O₅
Molecular Weight: 272.26
Beilstein Registry Number: 8503
EC Number: 266-769-1
MDL number: MFCD00006844
PubChem CID: 932

Item Number

N486154

Grouped product items
SKU	Size	Availability	Price	Qty
N486154-500g	500g	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$2,773.90

View related series

TAS2R39 Agonist TRPM3 Channel blocker

Basic Description

Synonyms	naringenin\|67604-48-2\|5,7-Dihydroxy-2-(4-hydroxyphenyl)chroman-4-one\|(+/-)-Naringenin\|4',5,7-Trihydroxyflavanone\|naringetol\|93602-28-9\|(-)-Naringenin\|( inverted exclamation markA)-Naringenin\|5,7-dihydroxy-2-(4-hydroxyphenyl)-2,3-dihydrochromen-4-one\|CHEMB
Specifications & Purity	Moligand™, from natural, ≥98%
Grade	from natural, Moligand™
Action Type	AGONIST, CHANNEL BLOCKER
Mechanism of action	Agonist of TAS2R39;Channel blocker of TRPM3
Product Description	Naringenin is a bioactive flavonoid found in citrus and grapefruit.Naringenin has been used in a study to compare its antigenotoxic and antioxidative activity with that of naringenin-oxime.

Associated Targets

CYP3A4 Tclin Cytochrome P450 3A4 0 Activities

Discover Target: CYP3A4

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

DPP4 Tclin Dipeptidyl peptidase 4 0 Activities

Discover Target: DPP4

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

CCNE1 Tchem G1/S-specific cyclin-E1 0 Activities

Discover Target: CCNE1

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

DGAT1 Tclin Diacylglycerol O-acyltransferase 1 0 Activities

Discover Target: DGAT1

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

GMNN Tbio Geminin 0 Activities

Discover Target: GMNN

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

RORC Tchem Nuclear receptor ROR-gamma 0 Activities

Discover Target: RORC

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

TRPM3 Tchem Transient receptor potential cation channel subfamily M member 3 1 Activities

Discover Target: TRPM3

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

FTL Tbio Ferritin light chain 0 Activities

Discover Target: FTL

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

KMT2A Tchem Histone-lysine N-methyltransferase 2A 0 Activities

Discover Target: KMT2A

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

TAS2R39 Tchem Taste receptor type 2 member 39 0 Activities

Discover Target: TAS2R39

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

POLI Tchem DNA polymerase iota 0 Activities

Discover Target: POLI

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

PDK1 Tchem [Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 1, mitochondrial 0 Activities

Discover Target: PDK1

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

ALOX12 Tchem Arachidonate 12-lipoxygenase, 12S-type 0 Activities

Discover Target: ALOX12

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

ALOX5 Tclin Arachidonate 5-lipoxygenase 0 Activities

Discover Target: ALOX5

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

LRAT Tbio Lecithin retinol acyltransferase 0 Activities

Discover Target: LRAT

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

CACNA1C Tclin Voltage-dependent L-type calcium channel subunit alpha-1C 0 Activities

Discover Target: CACNA1C

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

APEX1 Tchem DNA-(apurinic or apyrimidinic site) lyase 0 Activities

Discover Target: APEX1

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

ACHE Tclin Acetylcholinesterase 0 Activities

Discover Target: ACHE

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

BCHE Tclin Cholinesterase 0 Activities

Discover Target: BCHE

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

Names and Identifiers

IUPAC Name	5,7-dihydroxy-2-(4-hydroxyphenyl)-2,3-dihydrochromen-4-one
INCHI	InChI=1S/C15H12O5/c16-9-3-1-8(2-4-9)13-7-12(19)15-11(18)5-10(17)6-14(15)20-13/h1-6,13,16-18H,7H2
InChi Key	FTVWIRXFELQLPI-UHFFFAOYSA-N
Canonical SMILES	C1C(OC2=CC(=CC(=C2C1=O)O)O)C3=CC=C(C=C3)O
Isomeric SMILES	C1C(OC2=CC(=CC(=C2C1=O)O)O)C3=CC=C(C=C3)O
WGK Germany	3
Alternate CAS	480-41-1,67604-48-2
PubChem CID	932
NSC Number	11855
MeSH Entry Terms	(2S)-naringenin;4',5,7-trihydroxyflavanone;BE 14348A;BE-14348A;naringenin;naringenin-7-sulfate
Molecular Weight	272.26
Beilstein	8503
Reaxy-Rn	280888

Certificates

Certificate of Analysis(COA)

Enter Lot Number to search for COA:

Chemical and Physical Properties

Boil Point(°C)	577.47 °C
Melt Point(°C)	247-250°C

Safety and Hazards(GHS)

Pictogram(s)	GHS07
Signal	Warning
Hazard Statements	H315:Causes skin irritation H319:Causes serious eye irritation H335:May cause respiratory irritation
Precautionary Statements	P261:Avoid breathing dust/fume/gas/mist/vapors/spray. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses if present and easy to do - continue rinsing. P280:Wear protective gloves/protective clothing/eye protection/face protection. P302+P352:IF ON SKIN: wash with plenty of water. P321:Specific treatment (see ... on this label). P405:Store locked up. P501:Dispose of contents/container to ... P264:Wash hands [and …] thoroughly after handling. P271:Use only outdoors or in a well-ventilated area. P304+P340:IF INHALED: Remove person to fresh air and keep comfortable for breathing. P403+P233:Store in a well-ventilated place. Keep container tightly closed. P362+P364:Take off contaminated clothing and wash it before reuse. P264+P265:Wash hands [and …] thoroughly after handling. Do not touch eyes. P337+P317:If eye irritation persists: Get medical help. P332+P317:If skin irritation occurs: Get medical help. P319:Get medical help if you feel unwell.
WGK Germany	3
Reaxy-Rn	280888
Merck Index	6424

References

1. Straub I, Mohr F, Stab J, Konrad M, Philipp SE, Oberwinkler J, Schaefer M. (2013) Citrus fruit and fabacea secondary metabolites potently and selectively block TRPM3.. Br J Pharmacol, 168 (8): (1835-50). [PMID:23190005]
2. Xuemei Yu,Bruno Sainz,Susan L Uprichard. (2009-07-22) Development of a cell-based hepatitis C virus infection fluorescent resonance energy transfer assay for high-throughput antiviral compound screening.. Antimicrobial agents and chemotherapy, 53 ((10)): (4311-4319). [PMID:19620334]
3. Xin Xiong,Junjie Jiang,Jingli Duan,Yanming Xie,Jiannong Wang,Suodi Zhai. (2013-07-11) Development and validation of a sensitive liquid chromatography-tandem mass spectrometry method for the determination of naringin and its metabolite, naringenin, in human plasma.. Journal of chromatographic science, 52 ((7)): (654-660). [PMID:23839803]
4. M Surya Sandeep,V Sridhar,Y Puneeth,P Ravindra Babu,K Naveen Babu. (2013-07-26) Enhanced oral bioavailability of felodipine by naringenin in Wistar rats and inhibition of P-glycoprotein in everted rat gut sacs in vitro.. Drug development and industrial pharmacy, 40 ((10)): (1371-1377). [PMID:23883365]
5. S Bhattacharya,N Oksbjerg,J F Young,P B Jeppesen. (2013-11-12) Caffeic acid, naringenin and quercetin enhance glucose-stimulated insulin secretion and glucose sensitivity in INS-1E cells.. Diabetes, obesity & metabolism, 16 ((7)): (602-612). [PMID:24205999]
6. Nada Oršolić,Eleonora Goluža,Domagoj Dikić,Duje Lisičić,Kristijan Sašilo,Edi Rođak,Zelko Jeleč,Maja Vihnanek Lazarus,Tatjana Orct. (2013-11-26) Role of flavonoids on oxidative stress and mineral contents in the retinoic acid-induced bone loss model of rat.. European journal of nutrition, 53 ((5)): (1217-1227). [PMID:24271527]
7. Mai Furumiya,Katsuhisa Inoue,Chihiro Nishijima,Takahiro Yamashiro,Erina Inaoka,Kinya Ohta,Yayoi Hayashi,Hiroaki Yuasa. (2014-02-05) Noncompetitive inhibition of proton-coupled folate transporter by myricetin.. Drug metabolism and pharmacokinetics, 29 ((4)): (312-316). [PMID:24492671]
8. Abdul Wadood Khan,Sabna Kotta,Shahid Husain Ansari,Rakesh Kumar Sharma,Javed Ali. (2014-03-29) Enhanced dissolution and bioavailability of grapefruit flavonoid Naringenin by solid dispersion utilizing fourth generation carrier.. Drug development and industrial pharmacy, 41 ((5)): (772-779). [PMID:24669978]
9. Mohammad Ali Esmaeili,Mostafa Alilou. (2014-04-02) Naringenin attenuates CCl4 -induced hepatic inflammation by the activation of an Nrf2-mediated pathway in rats.. Clinical and experimental pharmacology & physiology, 41 ((6)): (416-422). [PMID:24684352]
10. N Singh,S Ravichandran,K Spelman,S D Fugmann,R Moaddel. (2014-04-08) The identification of a novel SIRT6 modulator from Trigonella foenum-graecum using ligand fishing with protein coated magnetic beads.. Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 968 (105-111). [PMID:24704183]
11. Qian Lou,Yali Liu,Yinyan Qi,Shuzhen Jiao,Feifei Tian,Ling Jiang,Yuejin Wang. (2014-05-03) Transcriptome sequencing and metabolite analysis reveals the role of delphinidin metabolism in flower colour in grape hyacinth.. Journal of experimental botany, 65 ((12)): (3157-3164). [PMID:24790110]
12. Sophie Dufay,Alan Worsley,Aymeric Monteillier,Charlotte Avanzi,Jaclyn Sy,Ting Fat Ng,Jean-Michel Garcia,Man-Fai Lam,Paul Vanhoutte,Ian C K Wong. (2014-05-16) Herbal tea extracts inhibit Cytochrome P450 3A4 in vitro.. The Journal of pharmacy and pharmacology, 66 ((10)): (1478-1490). [PMID:24824478]
13. Partha Pratim Roy,Sarbani Dey Ray,Supratim Ray. (2014-06-03) Combined experimental and in silico approaches for exploring antiperoxidative potential of structurally diverse classes of antioxidants on docetaxel-induced lipid peroxidation using 4-HNE as the model marker.. Bioorganic chemistry, 56 (1-7). [PMID:24887149]
14. Philipp Zeyhle,Judith S Bauer,Jörn Kalinowski,Kazuo Shin-ya,Harald Gross,Lutz Heide. (2014-06-04) Genome-based discovery of a novel membrane-bound 1,6-dihydroxyphenazine prenyltransferase from a marine actinomycete.. PloS one, 9 ((6)): (e99122-e99122). [PMID:24892559]
15. Panpan Guo,Lihua Dong,Wenying Yan,Jianceng Wei,Chunying Wang,Zijian Zhang. (2014-06-13) Simultaneous determination of linarin, naringenin and formononetin in rat plasma by LC-MS/MS and its application to a pharmacokinetic study after oral administration of Bushen Guchi Pill.. Biomedical chromatography : BMC, 29 ((2)): (246-253). [PMID:24920553]
16. Wei Zou,Yulong Luo,Menghua Liu,Si Chen,Sheng Wang,Yichu Nie,Guohua Cheng,Weiwei Su,Kejian Zhang. (2014-06-18) Human intestinal microbial metabolism of naringin.. European journal of drug metabolism and pharmacokinetics, 40 ((3)): (363-367). [PMID:24935725]
17. Gabriel Mazzi Leme,Francesco Cacciola,Paola Donato,Alberto José Cavalheiro,Paola Dugo,Luigi Mondello. (2014-06-22) Continuous vs. segmented second-dimension system gradients for comprehensive two-dimensional liquid chromatography of sugarcane (Saccharum spp.).. Analytical and bioanalytical chemistry, 406 ((18)): (4315-4324). [PMID:24951131]
18. Dima Albals,Ans Hendrickx,Lies Clincke,Bezhan Chankvetadze,Yvan Vander Heyden,Debby Mangelings. (2014-07-02) A chiral separation strategy for acidic drugs in capillary electrochromatography using both chlorinated and nonchlorinated polysaccharide-based selectors.. Electrophoresis, 35 ((19)): (2807-2818). [PMID:24981586]
19. ZiHuan Yang,Ao Pan,WuLin Zuo,JingHui Guo,WenLiang Zhou. (2014-07-06) Relaxant effect of flavonoid naringenin on contractile activity of rat colonic smooth muscle.. Journal of ethnopharmacology, 155 ((2)): (1177-1183). [PMID:24997391]
20. Brandon T Gufford,Gang Chen,Philip Lazarus,Tyler N Graf,Nicholas H Oberlies,Mary F Paine. (2014-07-11) Identification of diet-derived constituents as potent inhibitors of intestinal glucuronidation.. Drug metabolism and disposition: the biological fate of chemicals, 42 ((10)): (1675-1683). [PMID:25008344]
21. Peng-Fei Yue,Gang Li,Ji-Xiu Dan,Zhen-Feng Wu,Chang-Hong Wang,Wei-Feng Zhu,Ming Yang. (2014-08-27) Study on formability of solid nanosuspensions during solidification: II novel roles of freezing stress and cryoprotectant property.. International journal of pharmaceutics, 475 ((1-2)): (35-48). [PMID:25158243]
22. Chung-Hsi Chou,Cheng-Wei Liu,Deng-Jye Yang,Yi-Hsieng Samuel Wu,Yi-Chen Chen. (2014-08-31) Amino acid, mineral, and polyphenolic profiles of black vinegar, and its lipid lowering and antioxidant effects in vivo.. Food chemistry, 168 (63-69). [PMID:25172684]
23. Antonelle Pardo,Laetitia Mespouille,Bertrand Blankert,Patrick Trouillas,Mathieu Surin,Philippe Dubois,Pierre Duez. (2014-09-10) Quercetin-imprinted chromatographic sorbents revisited: optimization of synthesis and rebinding protocols for application to natural resources.. Journal of chromatography. A, 1364 (128-139). [PMID:25194624]
24. Clint M Alfaro,Agbo-Oma Uwakweh,Daniel A Todd,Brandie M Ehrmann,Nadja B Cech. (2014-10-01) Investigations of analyte-specific response saturation and dynamic range limitations in atmospheric pressure ionization mass spectrometry.. Analytical chemistry, 86 ((21)): (10639-10645). [PMID:25268329]
25. John T Barr,Jeffrey P Jones,Nicholas H Oberlies,Mary F Paine. (2014-10-19) Inhibition of human aldehyde oxidase activity by diet-derived constituents: structural influence, enzyme-ligand interactions, and clinical relevance.. Drug metabolism and disposition: the biological fate of chemicals, 43 ((1)): (34-41). [PMID:25326286]
26. Wei Zhang,Haishi Qiao,Yuanzi Lv,Jingjing Wang,Xiaoqing Chen,Yayi Hou,Renxiang Tan,Erguang Li. (2014-10-21) Apigenin inhibits enterovirus-71 infection by disrupting viral RNA association with trans-acting factors.. PloS one, 9 ((10)): (e110429-e110429). [PMID:25330384]
27. Burcu Bekdeşer,Nazan Durusoy,Mustafa Özyürek,Kubilay Güçlü,Reşat Apak. (2014-11-05) Optimization of microwave-assisted extraction of polyphenols from herbal teas and evaluation of their in vitro hypochlorous acid scavenging activity.. Journal of agricultural and food chemistry, 62 ((46)): (11109-11115). [PMID:25365495]
28. Kyoung Sik Park. (2014-11-29) Raspberry ketone, a naturally occurring phenolic compound, inhibits adipogenic and lipogenic gene expression in 3T3-L1 adipocytes.. Pharmaceutical biology, 53 ((6)): (870-875). [PMID:25429790]
29. Marely G Figueroa-Pérez,Nuria Elizabeth Rocha-Guzmán,Iza F Pérez-Ramírez,Edmundo Mercado-Silva,Rosalía Reynoso-Camacho. (2014-12-03) Metabolite profile, antioxidant capacity, and inhibition of digestive enzymes in infusions of peppermint (Mentha piperita) grown under drought stress.. Journal of agricultural and food chemistry, 62 ((49)): (12027-12033). [PMID:25439559]
30. Hiroki Yoshida,Hideaki Watanabe,Akiko Ishida,Wataru Watanabe,Keiko Narumi,Toshiyuki Atsumi,Chihiro Sugita,Masahiko Kurokawa. (2014-12-03) Naringenin suppresses macrophage infiltration into adipose tissue in an early phase of high-fat diet-induced obesity.. Biochemical and biophysical research communications, 454 ((1)): (95-101). [PMID:25450363]
31. Miriam Martínez-Huélamo,Sara Tulipani,Ramón Estruch,Elvira Escribano,Montserrat Illán,Dolores Corella,Rosa M Lamuela-Raventós. (2014-12-04) The tomato sauce making process affects the bioaccessibility and bioavailability of tomato phenolics: a pharmacokinetic study.. Food chemistry, 173 (864-872). [PMID:25466100]
32. Panpan Guo,Wenying Yan,Qingjie Han,Chunying Wang,Zijian Zhang. (2015-01-27) Simultaneous quantification of 25 active constituents in the total flavonoids extract from Herba Desmodii Styracifolii by high-performance liquid chromatography with electrospray ionization tandem mass spectrometry.. Journal of separation science, 38 ((7)): (1156-1163). [PMID:25620156]
33. Rui-Fang Li,Ying-Qian Feng,Jun-Hui Chen,Lin-Tong Ge,Shu-Yuan Xiao,Xue-Lan Zuo. (2015-02-11) Naringenin suppresses K562 human leukemia cell proliferation and ameliorates Adriamycin-induced oxidative damage in polymorphonuclear leukocytes.. Experimental and therapeutic medicine, 9 ((3)): (697-706). [PMID:25667616]
34. Milica Vujicic,Ivana Nikolic,Vassiliki G Kontogianni,Tamara Saksida,Pantelis Charisiadis,Zorana Orescanin-Dusic,Dusko Blagojevic,Stanislava Stosic-Grujicic,Andreas G Tzakos,Ivana Stojanovic. (2015-02-12) Methanolic extract of Origanum vulgare ameliorates type 1 diabetes through antioxidant, anti-inflammatory and anti-apoptotic activity.. The British journal of nutrition, 113 ((5)): (770-782). [PMID:25671817]
35. Ping Ji,Changmai Chen,Yanan Hu,Zixuan Zhan,Wei Pan,Rongrong Li,Erguang Li,Hui-Ming Ge,Guang Yang. (2015-03-07) Antiviral activity of Paulownia tomentosa against enterovirus 71 of hand, foot, and mouth disease.. Biological & pharmaceutical bulletin, 38 ((1)): (1-6). [PMID:25744451]
36. Longhai Dai,Can Liu,Yueming Zhu,Jiangsheng Zhang,Yan Men,Yan Zeng,Yuanxia Sun. (2015-03-12) Functional Characterization of Cucurbitadienol Synthase and Triterpene Glycosyltransferase Involved in Biosynthesis of Mogrosides from Siraitia grosvenorii.. Plant & cell physiology, 56 ((6)): (1172-1182). [PMID:25759326]
37. Sebastian Koob,Miguel Barrera,Ruchika Anand,Andreas S Reichert. (2015-03-15) The non-glycosylated isoform of MIC26 is a constituent of the mammalian MICOS complex and promotes formation of crista junctions.. Biochimica et biophysica acta, 1853 ((7)): (1551-1563). [PMID:25764979]
38. Manuel Y Schär,Peter J Curtis,Sara Hazim,Luisa M Ostertag,Colin D Kay,John F Potter,Aedín Cassidy. (2015-03-20) Orange juice-derived flavanone and phenolic metabolites do not acutely affect cardiovascular risk biomarkers: a randomized, placebo-controlled, crossover trial in men at moderate risk of cardiovascular disease.. The American journal of clinical nutrition, 101 ((5)): (931-938). [PMID:25788001]
39. Motofumi Kumazoe,Yoshinori Fujimura,Shiori Hidaka,Yoonhee Kim,Kanako Murayama,Mika Takai,Yuhui Huang,Shuya Yamashita,Motoki Murata,Daisuke Miura,Hiroyuki Wariishi,Mari Maeda-Yamamoto,Hirofumi Tachibana. (2015-04-01) Metabolic profiling-based data-mining for an effective chemical combination to induce apoptosis of cancer cells.. Scientific reports, 5 (9474-9474). [PMID:25824377]
40. Lizhen Qiao,Xianzhe Shi,Xin Lu,Guowang Xu. (2015-04-22) Preparation and evaluation of surface-bonded tricationic ionic liquid silica as stationary phases for high-performance liquid chromatography.. Journal of chromatography. A, 1396 (62-71). [PMID:25890438]
41. Szymon Bocian,Bogusław Buszewski. (2015-04-23) Comparison of retention properties of stationary phases imitated cell membrane in RP HPLC.. Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 990 (198-202). [PMID:25899871]
42. R N Gacche,R J Meshram,H D Shegokar,D S Gond,S S Kamble,V N Dhabadge,B G Utage,K K Patil,R A More. (2015-05-06) Flavonoids as a scaffold for development of novel anti-angiogenic agents: An experimental and computational enquiry.. Archives of biochemistry and biophysics, 577-578 (35-48). [PMID:25937258]
43. Yoshihiro Hirade,Naoyuki Kotoku,Kazuyoshi Terasaka,Yumiko Saijo-Hamano,Akemi Fukumoto,Hajime Mizukami. (2015-05-17) Identification and functional analysis of 2-hydroxyflavanone C-glucosyltransferase in soybean (Glycine max).. FEBS letters, 589 ((15)): (1778-1786). [PMID:25979175]
44. Hitoshi Ashida,Kiyonari Harada,Sakiho Mishima,Takakazu Mitani,Yoko Yamashita,Fumio Matsumura. (2015-05-20) Luteolin suppresses TCDD-induced wasting syndrome in a cultured adipocyte model.. Pesticide biochemistry and physiology, 120 (14-20). [PMID:25987215]
45. Saikh Mohammad Wabaidur,Yacine Badjah Hadj Ahmed,Zeid Abdullah Alothman,Munir Saeed Obbed,Nasser Mohamed AL-Harbi,Turki Mohammad AL-Turki. (2015-05-20) Ultra high performance liquid chromatography with mass spectrometry method for the simultaneous determination of phenolic constituents in honey from various floral sources using multiwalled carbon nanotubes as extraction sorbents.. Journal of separation science, 38 ((15)): (2597-2606). [PMID:25989240]
46. Ayuta Funaki,Toshiyuki Waki,Akio Noguchi,Yosuke Kawai,Satoshi Yamashita,Seiji Takahashi,Toru Nakayama. (2015-05-29) Identification of a Highly Specific Isoflavone 7-O-glucosyltransferase in the soybean (Glycine max (L.) Merr.).. Plant & cell physiology, 56 ((8)): (1512-1520). [PMID:26019269]
47. Yassine Chtourou,Ahlem Ben Slima,Radhouane Gdoura,Hamadi Fetoui. (2015-06-08) Naringenin Mitigates Iron-Induced Anxiety-Like Behavioral Impairment, Mitochondrial Dysfunctions, Ectonucleotidases and Acetylcholinesterase Alteration Activities in Rat Hippocampus.. Neurochemical research, 40 ((8)): (1563-1575). [PMID:26050208]
48. Jose Valdo Madeira,Gabriela Alves Macedo. (2015-06-18) Simultaneous extraction and biotransformation process to obtain high bioactivity phenolic compounds from Brazilian citrus residues.. Biotechnology progress, 31 ((5)): (1273-1279). [PMID:26081498]
49. Naiara Orrego-Lagarón,Miriam Martínez-Huélamo,Anna Vallverdú-Queralt,Rosa M Lamuela-Raventos,Elvira Escribano-Ferrer. (2015-06-18) High gastrointestinal permeability and local metabolism of naringenin: influence of antibiotic treatment on absorption and metabolism.. The British journal of nutrition, 114 ((2)): (169-180). [PMID:26083965]
50. Hyun Lim,Haeil Park,Hyun Pyo Kim. (2015-06-21) Effects of flavonoids on senescence-associated secretory phenotype formation from bleomycin-induced senescence in BJ fibroblasts.. Biochemical pharmacology, 96 ((4)): (337-348). [PMID:26093063]
51. Linlin Chang,Sheng Jia,Yingying Fu,Tianyi Zhou,Ji Cao,Qiaojun He,Bo Yang,Xian Li,Chongde Sun,Dan Su,Hong Zhu,Kunsong Chen. (2015-07-02) Ougan (Citrus reticulata cv. Suavissima) flavedo extract suppresses cancer motility by interfering with epithelial-to-mesenchymal transition in SKOV3 cells.. Chinese medicine, 10 (14-14). [PMID:26131016]
52. Oscar D Rangel-Huerta,Concepcion M Aguilera,Maria V Martin,Maria J Soto,Maria C Rico,Fernando Vallejo,Francisco Tomas-Barberan,Antonio J Perez-de-la-Cruz,Angel Gil,Maria D Mesa. (2015-07-03) Normal or High Polyphenol Concentration in Orange Juice Affects Antioxidant Activity, Blood Pressure, and Body Weight in Obese or Overweight Adults.. The Journal of nutrition, 145 ((8)): (1808-1816). [PMID:26136593]
53. Shingo Miyata,Jun Inoue,Makoto Shimizu,Ryuichiro Sato. (2015-07-05) Xanthohumol Improves Diet-induced Obesity and Fatty Liver by Suppressing Sterol Regulatory Element-binding Protein (SREBP) Activation.. The Journal of biological chemistry, 290 ((33)): (20565-20579). [PMID:26140926]
54. Ming-Jun Tsai,Yaw-Bin Huang,Jhih-Wun Fang,Yaw-Syan Fu,Pao-Chu Wu. (2015-07-15) Preparation and Characterization of Naringenin-Loaded Elastic Liposomes for Topical Application.. PloS one, 10 ((7)): (e0131026-e0131026). [PMID:26158639]
55. Tsiry Rasamiravaka,Olivier M Vandeputte,Laurent Pottier,Joelle Huet,Christian Rabemanantsoa,Martin Kiendrebeogo,Abel Andriantsimahavandy,Andry Rasamindrakotroka,Caroline Stévigny,Pierre Duez,Mondher El Jaziri. (2015-07-18) Pseudomonas aeruginosa Biofilm Formation and Persistence, along with the Production of Quorum Sensing-Dependent Virulence Factors, Are Disrupted by a Triterpenoid Coumarate Ester Isolated from Dalbergia trichocarpa, a Tropical Legume.. PloS one, 10 ((7)): (e0132791-e0132791). [PMID:26186595]
56. Nor Nadiah Abdul Karim Shah,Russly Abdul Rahman,Rosnah Shamsuddin,Noranizan Mohd Adzahan. (2015-08-06) Effects of pectinase\xa0clarification treatment on phenolic compounds of pummelo (Citrus grandis l. Osbeck) fruit juice.. Journal of food science and technology, 52 ((8)): (5057-5065). [PMID:26243926]
57. Jason Liang Pin Ng,Samira Hassan,Thy T Truong,Charles H Hocart,Carole Laffont,Florian Frugier,Ulrike Mathesius. (2015-08-09) Flavonoids and Auxin Transport Inhibitors Rescue Symbiotic Nodulation in the Medicago truncatula Cytokinin Perception Mutant cre1.. The Plant cell, 27 ((8)): (2210-2226). [PMID:26253705]
58. Rubén Álvarez-Álvarez,Alma Botas,Silvia M Albillos,Angel Rumbero,Juan F Martín,Paloma Liras. (2015-11-11) Molecular genetics of naringenin biosynthesis, a typical plant secondary metabolite produced by Streptomyces clavuligerus.. Microbial cell factories, 14 (178-178). [PMID:26553209]
59. Miriam Martínez-Huélamo,Sara Tulipani,Olga Jáuregui,Palmira Valderas-Martinez,Anna Vallverdú-Queralt,Ramón Estruch,Xavier Torrado,Rosa M Lamuela-Raventós. (2015-11-19) Sensitive and Rapid UHPLC-MS/MS for the Analysis of Tomato Phenolics in Human Biological Samples.. Molecules (Basel, Switzerland), 20 ((11)): (20409-20425). [PMID:26580589]
60. Beata Żyszka,Mirosław Anioł,Jacek Lipok. (2017-05-13) Modulation of the growth and metabolic response of cyanobacteria by the multifaceted activity of naringenin.. PloS one, 12 ((5)): (e0177631-e0177631). [PMID:28498848]
61. Ruibing Chen,Xianghui Chen,Tingting Zhu,Jianghua Liu,Xing Xiang,Jian Yu,Hexin Tan,Shouhong Gao,Qing Li,Yichao Fang,Wansheng Chen,Lei Zhang,Baokang Huang. (2018-07-18) Integrated Transcript and Metabolite Profiles Reveal That EbCHI Plays an Important Role in Scutellarin Accumulation in Erigeron breviscapus Hairy Roots.. Frontiers in plant science, 9 (789-789). [PMID:30013578]
62. Zhaorui Meng,Jing Zhao,Hongxia Duan,Yuanyuan Guan,Longshan Zhao. (2018-09-03) Green and efficient extraction of four bioactive flavonoids from Pollen Typhae by ultrasound-assisted deep eutectic solvents extraction.. Journal of pharmaceutical and biomedical analysis, 161 (246-253). [PMID:30172879]
63. Barbara Napoli,Sentiljana Gumeni,Alessia Forgiarini,Marianna Fantin,Concetta De Filippis,Elena Panzeri,Chiara Vantaggiato,Genny Orso. (2019-12-06) Naringenin Ameliorates Drosophila ReepA Hereditary Spastic Paraplegia-Linked Phenotypes.. Frontiers in neuroscience, 13 (1202-1202). [PMID:31803000]
64. Katarzyna Stec,Joanna Kozłowska,Anna Wróblewska-Kurdyk,Bożena Kordan,Mirosław Anioł,Beata Gabryś. (2020-07-17) Effect of Naringenin and Its Derivatives on the Probing Behavior of Myzus persicae (Sulz.).. Molecules (Basel, Switzerland), 25 ((14)): [PMID:32668610]
65. Xingyuan Shi,Xueping Luo,Ting Chen,Wei Guo,Chanjin Liang,Sihan Tang,Jianming Mo. (2021-02-02) Naringenin inhibits migration, invasion, induces apoptosis in human lung cancer cells and arrests tumour progression in vitro.. Journal of cellular and molecular medicine, 25 ((5)): (2563-2571). [PMID:33523599]
66. Malaysha Rice,Bokey Wong,Mare Oja,Kelley Samuels,Alicia K Williams,Jenny Fong,Anne-Marie Sapse,Uko Maran,Ekaterina A Korobkova. (2021-02-03) A role of flavonoids in cytochrome c-cardiolipin interactions.. Bioorganic & medicinal chemistry, 33 (116043-116043). [PMID:33530021]
67. Talia Hatkevich,Joseph Ramos,Idalys Santos-Sanchez,Yashomati M Patel. (2014-06-03) A naringenin-tamoxifen combination impairs cell proliferation and survival of MCF-7 breast cancer cells.. Experimental cell research, 327 ((2)): (331-339). [PMID:24881818]
68. Antonella Smeriglio,Domenico Trombetta,Daniele Marcoccia,Laura Narciso,Alberto Mantovani,Stefano Lorenzetti. (2014-06-26) Intracellular distribution and biological effects of phytochemicals in a sex steroid- sensitive model of human prostate adenocarcinoma.. Anti-cancer agents in medicinal chemistry, 14 ((10)): (1386-1396). [PMID:24962071]
69. Joo Ae Kim,Somyoung Lee,Da-Eun Kim,Moonil Kim,Byoung-Mog Kwon,Dong Cho Han. (2015-04-05) Fisetin, a dietary flavonoid, induces apoptosis of cancer cells by inhibiting HSF1 activity through blocking its binding to the hsp70 promoter.. Carcinogenesis, 36 ((6)): (696-706). [PMID:25840992]
70. Vladimir Ajdžanović,V Jakovljević,D Milenković,A Konić-Ristić,J Živanović,I Jarić,V Milošević. (2015-06-24) Positive effects of naringenin on near-surface membrane fluidity in human erythrocytes.. Acta physiologica Hungarica, 102 ((2)): (131-136). [PMID:26100302]
71. Salim S Al-Rejaie,Abdulaziz M Aleisa,Hatem M Abuohashish,Mihir Y Parmar,Mohammad S Ola,Abdulaziz A Al-Hosaini,Mohammed M Ahmed. (2015-07-19) Naringenin neutralises oxidative stress and nerve growth factor discrepancy in experimental diabetic neuropathy.. Neurological research, 37 ((10)): (924-933). [PMID:26187552]
72. Tsz Yan Wong,Shu-mei Lin,Lai K Leung. (2015-08-25) The Flavone Luteolin Suppresses SREBP-2 Expression and Post-Translational Activation in Hepatic Cells.. PloS one, 10 ((8)): (e0135637-e0135637). [PMID:26302339]
73. Mirko De Rosso,Annarita Panighel,Antonio Dalla Vedova,Massimo Gardiman,Riccardo Flamini. (2015-10-09) Characterization of Non-Anthocyanic Flavonoids in Some Hybrid Red Grape Extracts Potentially Interesting for Industrial Uses.. Molecules (Basel, Switzerland), 20 ((10)): (18095-18106). [PMID:26445038]
74. Guobin Han,Qiaoling Zeng,Zhongwei Jiang,Tiantian Xing,Chengzhi Huang,Yuanfang Li. (2017-01-22) MIL-101(Cr) as matrix for sensitive detection of quercetin by matrix-assisted laser desorption/ionization mass spectrometry.. Talanta, 164 (355-361). [PMID:28107941]
75. Thomas Uebel,Markus Wilken,Hung Vu Chi,Melanie Esselen. (2019-05-03) In vitro combinatory cytotoxicity of hepatocarcinogenic asarone isomers and flavonoids.. Toxicology in vitro : an international journal published in association with BIBRA, 60 (19-26). [PMID:31047974]
76. Sema Demirci Çekiç,Asli Neslihan Avan,Seda Uzunboy,Reşat Apak. (2015-03-04) A colourimetric sensor for the simultaneous determination of oxidative status and antioxidant activity on the same membrane: N,N-dimethyl-p-phenylene diamine (DMPD) on Nafion.. Analytica chimica acta, 865 (60-70). [PMID:25732585]

Solution Calculators

Molarity Calculator

Determine the necessary mass, volume, or concentration for preparing a solution.

Dilution Calculator

Determine the dilution needed to prepare a stock solution.