A flavanone glycoside. Neuroprotective. Activates Nrf2. Inhibits expression of pro-inflammatory mediators.
Storage Temp
Argon charged
Shipped In
Normal
Grade
analytical standard, Moligand™
Action Type
INHIBITOR
Mechanism of action
Inhibitor of OATP1A2
Note
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour. Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
Product Description
Naringin has been used: • as a bitter tastant to compare the behavioral response of the Drosophila larva and adult • to study its anti-inflammatory property and to determine its effect on nucleus pulposus (NP) cells • to determine its effect on bone metabolism like osteogenic differentiation, inhibition of osteoclast formation
1.Bailey DG, Dresser GK, Leake BF, Kim RB. (2007) Naringin is a major and selective clinical inhibitor of organic anion-transporting polypeptide 1A2 (OATP1A2) in grapefruit juice.. Clin Pharmacol Ther, 81 (4):(495-502). [PMID:17301733]
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F2429291