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NBI-31772 hydrate - 98%, high purity , CAS No.N658887

  • ≥98%
Item Number
N658887
Grouped product items
SKUSizeAvailabilityPrice Qty
N658887-5mg
5mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$470.90
View related series
IGF-1R Protein Tyrosine Kinase/RTK

Basic Description

Specifications & Purity98%
Storage TempStore at 2-8°C,Argon charged
Shipped InWet ice
Product Description

NBI-31772 hydrate is a potent inhibitor of interaction between insulin-like growth factor (IGF) and IGF-binding proteins (IGFBPs) . NBI-31772 hydrate is also a nonpeptide ligand that releases bioactive IGF-I from the IGF-I/IGFBP-3 complex ( K i s=1-24 nM

Appearance:Solid

In Vivo:NBI-31772 (5-100 μg; icv; immediately or at 1, 2, or, 3 hours after MCAO) at the time of ischemia onset also dose-dependently reduced infarct size, and the highest dose (100 μg) significantly reduced both total and cortical infarct volume. MCE has no

Biological Activity:NBI-31772 hydrate is a potent inhibitor of interaction between insulin-like growth factor (IGF) and IGF-binding proteins (IGFBPs) . NBI-31772 hydrate is also a nonpeptide ligand that releases bioactive IGF-I from the IGF-I/IGFBP-3 complex ( K i s=1-24 nM

Names and Identifiers

Canonical SMILES O=C(C1=CC(O)=C(O)C=C1)C2=NC(C(O)=O)=CC3=C2C=C(O)C(O)=C3.[7/4].O
Molecular Weight 372.82

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