NDSB-221 - ≥97%, high purity , CAS No.160788-56-7

  • ≥97%
Item Number
N276111
Grouped product items
SKUSizeAvailabilityPrice Qty
N276111-5g
5g
In stock
$125.90
N276111-25g
25g
In stock
$422.90

Discover NDSB-221 by Aladdin Scientific in ≥97% for only $125.90. Available - in Ligands at Aladdin Scientific. Zwitterionic non-detergent sulfobetaine. Tags: .

Basic Description

SynonymsNDSB 221 | CS-0112975 | 3-(1-methylpiperidinio)-1-propanesulfonate | J-009754 | SCHEMBL2396073 | non-detergent sulfobetaine 221 | DTXSID001213424 | 3-(1-Methylpiperidin-1-ium-1-yl)propane-1-sulfonate | HY-135463 | CHEBI:63318 | LCZC1460 | non detergent su
Specifications & Purity≥97%
Storage TempRoom temperature,Argon charged
Shipped InNormal
Product Description

Product description
NDSB 221 is a nondetergent sulfobetaine that has been found to improve unfolding reversibility.
Product Application

NDSB 221 has been used in a study to identify a novel ligand binding site in phosphoserine phosphatase from Thermococcus onnurineus. It has also been used in a study to investigate its effects on acidic fibroblast growth factor (aFGF).
Non-detergent sulfobetaine is a compound used for non-denaturing protien purification. Increases the extraction yield of membrane, nuclear and cytoskeletal associated proteins. Zwitterionic over a wide pH range, easily removed by dialysis and no significant absorption in the near UV range. Specific applications include microsomal protein extraction, nuclear protein recovery, precipitation reduction in IEF, and membrane-bound protease purification. The typical usage concentration is 0.5 - 2.0 M.


Names and Identifiers

Pubchem Sid488196547
IUPAC Name 3-(1-methylpiperidin-1-ium-1-yl)propane-1-sulfonate
INCHI InChI=1S/C9H19NO3S/c1-10(6-3-2-4-7-10)8-5-9-14(11,12)13/h2-9H2,1H3
InChi Key DQNQWAVIDNVATL-UHFFFAOYSA-N
Canonical SMILES C[N+]1(CCCCC1)CCCS(=O)(=O)[O-]
Isomeric SMILES C[N+]1(CCCCC1)CCCS(=O)(=O)[O-]
PubChem CID 10130697
Molecular Weight 221.32

Certificates

Certificate of Analysis(COA)

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4 results found

Lot NumberCertificate TypeDateItem
I2320758Certificate of AnalysisJul 11, 2024 N276111
I2320759Certificate of AnalysisJul 11, 2024 N276111
I2320761Certificate of AnalysisJul 09, 2024 N276111
I2320760Certificate of AnalysisJul 09, 2024 N276111

Chemical and Physical Properties

SolubilitySoluble in water to 100 mM
SensitivityMoisture sensitive

Safety and Hazards(GHS)

Pictogram(s) GHS05
Signal Danger
Hazard Statements

H314:Causes severe skin burns and eye damage

Precautionary Statements

P280:Wear protective gloves/protective clothing/eye protection/face protection.

P321:Specific treatment (see ... on this label).

P405:Store locked up.

P501:Dispose of contents/container to ...

P264:Wash hands [and …] thoroughly after handling.

P260:Do not breathe dust/fume/gas/mist/vapors/spray.

P301+P330+P331:IF SWALLOWED: Rinse mouth. Do NOT induce vomiting.

P304+P340:IF INHALED: Remove person to fresh air and keep comfortable for breathing.

P363:Wash contaminated clothing before reuse.

P305+P354+P338:IF IN EYES: Immediately rinse with water for several minutes. Remove contact lenses if present and easy to do. Continue rinsing.

P302+P361+P354:IF ON SKIN: Take off Immediately all contaminated clothing. Immediately rinse with water for several minutes.

P316:Get emergency medical help immediately.

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