| SKU | Size | Availability | Price | Qty |
|---|---|---|---|---|
| N408193-1ml | 1ml | Available within 4-8 weeks(?) Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience! | $73.90 |
| Specifications & Purity | 10mM in DMSO |
|---|---|
| Biochemical and Physiological Mechanisms | Neohesperidin (NSC 31048), a flavanone glycoside found in citrus fruits, is an antioxidant agent. |
| Storage Temp | Store at -80°C |
| Shipped In | Ice chest + Ice pads |
| Product Description | Information Neohesperidin (NSC 31048), a flavanone glycoside found in citrus fruits, is an antioxidant agent. Neohesperidin, a flavanone glycoside found in citrus fruits, is an antioxidant agent. Neohesperidin is an antioxidant agent with an IC50 of 22.31 μg/ml in the 1,1-diphenyl-2-picryldydrazyl (DPPH) radical-scavenging assay. Neohesperidin (50 mg/kg) significantly inhibits HCl/ethanol-induced gastric lesions, and increases the mucus content. In pylorus ligated rats, neohesperidin (50 mg/kg) significantly decreases the volume of gastric secretion and gastric acid output, and increases the pH. In addition, Neohesperidin inhibits the growth of Caco-2, CEM/ADR5000 and CCRF-CEM leukaemia cells with IC50 of 0.17, 0.17 and 0.12 mM, respectively. In vivo
cell lines： Concentrations： Incubation Time： Powder Purity:≥98% |
| Canonical SMILES | COC1=CC(=CC(=C1)C2CC(=O)C3=C(O)C=C(OC4OC(CO)C(O)C(O)C4OC5OC(C)C(O)C(O)C5O)C=C3O2)O |
|---|---|
| Molecular Weight | 610.56 |
Enter Lot Number to search for COA:
| 1. Yu Bo, Luo Shiyu, Ding Yuhan, Gong Zijie, Nie Ting. (2022) Insights into glycosidic bond specificity of an engineered selective α-L-rhamnosidase N12-Rha via activity assays and molecular modelling. AMB Express, 12 (1): (1-14). [PMID:36370155] [10.1186/s13568-022-01489-5] |
| 2. Dan Yu, Fei Liu, Changdong Zou, Xiao Yang. (2023) Municipal green waste promotes iron release from steelmaking slag in water. RESOURCES CONSERVATION AND RECYCLING, 188 (106722). [PMID:] [10.1016/j.resconrec.2022.106722] |
| 3. Jie Zhao, Lin Huang, Renjie Li, Zhuangwei Zhang, Jin Chen, Hongjin Tang. (2022) Insights from multi-spectroscopic analysis and molecular modeling to understand the structure–affinity relationship and the interaction mechanism of flavonoids with gliadin. Food & Function, 13 (9): (5061-5074). [PMID:35404372] [10.1039/D1FO03816H] |
| 4. Lu Shao Hua, Zhang Ming Cai, Zhai Hong Lin, Bi Ke Xin, Zhao Bing Qiang. (2022) Rapid Determination in the Quality Control of Chinese Patent Medicine. Journal of Pharmaceutical Innovation, 17 (4): (1305-1313). [PMID:] [10.1007/s12247-021-09608-8] |
| 5. Lingrong Wen, Mingyang He, Chunxiao Yin, Yueming Jiang, Donghui Luo, Bao Yang. (2021) Phenolics in Citrus aurantium fruit identified by UHPLC-MS/MS and their bioactivities. LWT-FOOD SCIENCE AND TECHNOLOGY, 147 (111671). [PMID:] [10.1016/j.lwt.2021.111671] |
| 6. Hongjin Tang, Lin Huang, Dongsheng Zhao, Chunyong Sun, Ping Song. (2020) Interaction mechanism of flavonoids on bovine serum albumin: Insights from molecular property-binding affinity relationship. SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY, 239 (118519). [PMID:32480277] [10.1016/j.saa.2020.118519] |
| 7. Jie Zhao, Lin Huang, Chunyong Sun, Dongsheng Zhao, Hongjin Tang. (2020) Studies on the structure-activity relationship and interaction mechanism of flavonoids and xanthine oxidase through enzyme kinetics, spectroscopy methods and molecular simulations. FOOD CHEMISTRY, 323 (126807). [PMID:32330646] [10.1016/j.foodchem.2020.126807] |
| 1. Yu Bo, Luo Shiyu, Ding Yuhan, Gong Zijie, Nie Ting. (2022) Insights into glycosidic bond specificity of an engineered selective α-L-rhamnosidase N12-Rha via activity assays and molecular modelling. AMB Express, 12 (1): (1-14). [PMID:36370155] [10.1186/s13568-022-01489-5] |
| 2. Dan Yu, Fei Liu, Changdong Zou, Xiao Yang. (2023) Municipal green waste promotes iron release from steelmaking slag in water. RESOURCES CONSERVATION AND RECYCLING, 188 (106722). [PMID:] [10.1016/j.resconrec.2022.106722] |
| 3. Jie Zhao, Lin Huang, Renjie Li, Zhuangwei Zhang, Jin Chen, Hongjin Tang. (2022) Insights from multi-spectroscopic analysis and molecular modeling to understand the structure–affinity relationship and the interaction mechanism of flavonoids with gliadin. Food & Function, 13 (9): (5061-5074). [PMID:35404372] [10.1039/D1FO03816H] |
| 4. Lu Shao Hua, Zhang Ming Cai, Zhai Hong Lin, Bi Ke Xin, Zhao Bing Qiang. (2022) Rapid Determination in the Quality Control of Chinese Patent Medicine. Journal of Pharmaceutical Innovation, 17 (4): (1305-1313). [PMID:] [10.1007/s12247-021-09608-8] |
| 5. Lingrong Wen, Mingyang He, Chunxiao Yin, Yueming Jiang, Donghui Luo, Bao Yang. (2021) Phenolics in Citrus aurantium fruit identified by UHPLC-MS/MS and their bioactivities. LWT-FOOD SCIENCE AND TECHNOLOGY, 147 (111671). [PMID:] [10.1016/j.lwt.2021.111671] |
| 6. Hongjin Tang, Lin Huang, Dongsheng Zhao, Chunyong Sun, Ping Song. (2020) Interaction mechanism of flavonoids on bovine serum albumin: Insights from molecular property-binding affinity relationship. SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY, 239 (118519). [PMID:32480277] [10.1016/j.saa.2020.118519] |
| 7. Jie Zhao, Lin Huang, Chunyong Sun, Dongsheng Zhao, Hongjin Tang. (2020) Studies on the structure-activity relationship and interaction mechanism of flavonoids and xanthine oxidase through enzyme kinetics, spectroscopy methods and molecular simulations. FOOD CHEMISTRY, 323 (126807). [PMID:32330646] [10.1016/j.foodchem.2020.126807] |
