NH-3 , CAS No.N612290, Antagonist of Thyroid hormone receptor-α;Antagonist of Thyroid hormone receptor-β

Item Number

N612290

Grouped product items
SKU	Size	Availability	Price	Qty
N612290-5mg	5mg	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$1,334.90
N612290-25mg	25mg	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$1,820.90

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Basic Description

Synonyms	NH-3\|447415-26-1\|thyromimetic, 5b\|54KY638G8W\|UNII-54KY638G8W\|CHEMBL109279\|Acetic acid, (4-((4-hydroxy-3-(1-methylethyl)-5-((4-nitrophenyl)ethynyl)phenyl)methyl)-3,5-dimethylphenoxy)-\|Acetic acid, 2-(4-((4-hydroxy-3-(1-methylethyl)-5-(2-(4-nitrophenyl)ethy
Grade	Moligand™
Action Type	ANTAGONIST
Mechanism of action	Antagonist of Thyroid hormone receptor-α;Antagonist of Thyroid hormone receptor-β

Associated Targets

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

Names and Identifiers

IUPAC Name	2-[4-[[4-hydroxy-3-[2-(4-nitrophenyl)ethynyl]-5-propan-2-ylphenyl]methyl]-3,5-dimethylphenoxy]acetic acid
INCHI	InChI=1S/C28H27NO6/c1-17(2)25-14-21(15-26-18(3)11-24(12-19(26)4)35-16-27(30)31)13-22(28(25)32)8-5-20-6-9-23(10-7-20)29(33)34/h6-7,9-14,17,32H,15-16H2,1-4H3,(H,30,31)
InChi Key	IXMROOKFPWGDGF-UHFFFAOYSA-N
Canonical SMILES	OC(=O)COc1cc(C)c(c(c1)C)Cc1cc(C(C)C)c(c(c1)C#Cc1ccc(cc1)[N+](=O)[O-])O
Isomeric SMILES	CC1=CC(=CC(=C1CC2=CC(=C(C(=C2)C(C)C)O)C#CC3=CC=C(C=C3)[N+](=O)[O-])C)OCC(=O)O
PubChem CID	10027822

PubChem CID

ChEMBL Ligand

BindingDB Ligand

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Basic Description