Your company account is blocked and you cannot place orders. If you have questions, please contact your company administrator.

Niazinin - 99%, high purity , CAS No.147821-57-6

  • ≥99%
Item Number
N646390
Grouped product items
SKUSizeAvailabilityPrice Qty
N646390-1mg
1mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$309.90
N646390-5mg
5mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$650.90
N646390-10mg
10mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$980.90

Basic Description

SynonymsNiazinin | NIAZININ A | HY-N8471 | MS-25259 | CS-0144627 | AKOS040762117 | O-Methyl (4-(((2S,3R,4R,5R,6S)-3,4,5-trihydroxy-6-methyltetrahydro-2H-pyran-2-yl)oxy)benzyl)carbamothioate | O-methyl N-[[4-[(2S,3R,4R,5R,6S)-3,4,5-trihydroxy-6-methyloxan-2-yl]oxy
Specifications & Purity≥99%
Biochemical and Physiological MechanismsNiazinin is a thiocarbamate glycoside with antileishmanial activities, with an IC 50 value of 5.25 μM. Niazinin also shows a binding affinity with the target protein 3CL protease . Niazinin has promising leishmanicidal, anti-inflammatory and anti-pyretic
Storage TempProtected from light,Store at -80°C
Shipped InIce chest + Ice pads
Product Description

Niazinin is a thiocarbamate glycoside with antileishmanial activities, with an IC 50 value of 5.25 μM. Niazinin also shows a binding affinity with the target protein 3CL protease. Niazinin has promising leishmanicidal, anti-inflammatory and anti-pyretic activity.

In Vitro

Niazinin, is cytotoxic at substantially higher concentration (CC50 of 31.6 µM) than its antileishmanial concentration (IC50 of 5.25 µM). MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Form:Solid

Names and Identifiers

IUPAC Name O-methyl N-[[4-[(2S,3R,4R,5R,6S)-3,4,5-trihydroxy-6-methyloxan-2-yl]oxyphenyl]methyl]carbamothioate
INCHI InChI=1S/C15H21NO6S/c1-8-11(17)12(18)13(19)14(21-8)22-10-5-3-9(4-6-10)7-16-15(23)20-2/h3-6,8,11-14,17-19H,7H2,1-2H3,(H,16,23)/t8-,11-,12+,13+,14-/m0/s1
InChi Key ZOIAMMQYAZSWRX-CNJBRALLSA-N
Canonical SMILES CC1C(C(C(C(O1)OC2=CC=C(C=C2)CNC(=S)OC)O)O)O
Isomeric SMILES C[C@H]1[C@@H]([C@H]([C@H]([C@@H](O1)OC2=CC=C(C=C2)CNC(=S)OC)O)O)O
Alternate CAS 147821-57-6
PubChem CID 10088810
Molecular Weight 343.40

Certificates

C of A & Other Certificates(BSE/TSE, COO)

Chemical and Physical Properties

SolubilityDMSO : ≥ 50 mg/mL (145.60 mM)

Related Documents

Solution Calculators