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NIBR-17 - 98%, high purity , CAS No.944396-88-7

≥98%

CAS#: 944396-88-7
Formula: C₁₈H₂₀N₈O₂
Molecular Weight: 380.4
PubChem CID: 53322732

Item Number

N412353

Grouped product items
SKU	Size	Availability	Price
N412353-1mg	1mg	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$182.90
N412353-5mg	5mg	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$371.90
N412353-10mg	10mg	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$552.90
N412353-25mg	25mg	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$885.90
N412353-50mg	50mg	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$1,199.90
N412353-100mg	100mg	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$1,599.90

View related series

PI3K PI3K/Akt/mTOR

Basic Description

Specifications & Purity	≥98%
Biochemical and Physiological Mechanisms	NIBR-17 is a pan class I PI3K inhibitor with IC50 of 1 nM, 9.2 nM, 9 nM and 20 nM for PI3KKα, PI3KKβ, PI3KKγ and PI3KKδ, respectively .
Storage Temp	Store at -20°C
Shipped In	Ice chest + Ice pads
Product Description	Information NIBR-17 is a pan class I PI3K inhibitor with IC50 of 1 nM, 9.2 nM, 9 nM and 20 nM for PI3KKα, PI3KKβ, PI3KKγ and PI3KKδ, respectively .

Associated Targets

PIK3CG Tclin Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform 1 Activities

Discover Target: PIK3CG

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

PIK3CA Tclin Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform 0 Activities

Discover Target: PIK3CA

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

PIK3CB Tchem Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform 0 Activities

Discover Target: PIK3CB

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

PIK3CD Tclin Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform 1 Activities

Discover Target: PIK3CD

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

PI4KB Tchem Phosphatidylinositol 4-kinase beta 0 Activities

Discover Target: PI4KB

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

PIK3C3 Tchem Phosphatidylinositol 3-kinase catalytic subunit type 3 0 Activities

Discover Target: PIK3C3

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

MTOR Tclin Serine/threonine-protein kinase mTOR 0 Activities

Discover Target: MTOR

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

Names and Identifiers

IUPAC Name	6-(2-aminopyrimidin-5-yl)-N-(6-methoxypyridin-3-yl)-2-morpholin-4-ylpyrimidin-4-amine
INCHI	InChI=1S/C18H20N8O2/c1-27-16-3-2-13(11-20-16)23-15-8-14(12-9-21-17(19)22-10-12)24-18(25-15)26-4-6-28-7-5-26/h2-3,8-11H,4-7H2,1H3,(H2,19,21,22)(H,23,24,25)
InChi Key	XZTYTIOLZIKUJR-UHFFFAOYSA-N
Canonical SMILES	COC1=NC=C(C=C1)NC2=NC(=NC(=C2)C3=CN=C(N=C3)N)N4CCOCC4
Isomeric SMILES	COC1=NC=C(C=C1)NC2=NC(=NC(=C2)C3=CN=C(N=C3)N)N4CCOCC4
PubChem CID	53322732
Molecular Weight	380.4

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