Determine the necessary mass, volume, or concentration for preparing a solution.
Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) |
---|
SKU | Size | Availability | Price | Qty |
---|---|---|---|---|
N159515-250mg | 250mg | In stock | $58.90 | |
N159515-1g | 1g | Available within 4-8 weeks(?) Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience! | $181.90 | |
N159515-5g | 5g | Available within 4-8 weeks(?) Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience! | $816.90 |
DNA alkylator and cross-linking agent
Synonyms | Nimustine hydrochloride|55661-38-6|Nimustine HCl|ACNU|Nidran|Nidran hydrochloride|Nimustine (hydrochloride)|52208-23-8|Nimustina clorhidrato|CS 439 HCl|Nimustine hydrochloride [JAN]|NSC-245,382|DFR965WKBU|CHEBI:7576|3-((4-Amino-2-methyl-5-pyrimidinyl)meth |
---|---|
Specifications & Purity | ≥98%(HPLC)(T) |
Biochemical and Physiological Mechanisms | DNA alkylator and cross-linking agent. Antineoplastic agent. Active in vivo . |
Shipped In | Normal |
Note | Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour. Toxic, refer to SDS for further information. Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details. |
Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) |
---|
Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) |
---|
Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) |
---|
IUPAC Name | 3-[(4-amino-2-methylpyrimidin-5-yl)methyl]-1-(2-chloroethyl)-1-nitrosourea;hydrochloride |
---|---|
INCHI | InChI=1S/C9H13ClN6O2.ClH/c1-6-12-4-7(8(11)14-6)5-13-9(17)16(15-18)3-2-10;/h4H,2-3,5H2,1H3,(H,13,17)(H2,11,12,14);1H |
InChi Key | KPMKNHGAPDCYLP-UHFFFAOYSA-N |
Canonical SMILES | CC1=NC=C(C(=N1)N)CNC(=O)N(CCCl)N=O.Cl |
Isomeric SMILES | CC1=NC=C(C(=N1)N)CNC(=O)N(CCCl)N=O.Cl |
RTECS | YR8450000 |
PubChem CID | 91657 |
Molecular Weight | 309.15 |
Reaxy-Rn | 4220350 |
Enter Lot Number to search for COA:
Solubility | Soluble in Methanol; Insoluble in Benzene,Ether,Chloroform |
---|---|
Sensitivity | light sensitive |
Melt Point(°C) | 186°C(lit.) |
Pictogram(s) | GHS06 |
---|---|
Signal | Danger |
Hazard Statements | H301:Toxic if swallowed |
Precautionary Statements | P321:Specific treatment (see ... on this label). P405:Store locked up. P501:Dispose of contents/container to ... P264:Wash hands [and …] thoroughly after handling. P270:Do not eat, drink or smoke when using this product. P330:Rinse mouth. P301+P316:IF SWALLOWED: Get emergency medical help immediately. |
RTECS | YR8450000 |
Reaxy-Rn | 4220350 |
Merck Index | 6553 |