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Nimustine Hydrochloride - >98.0%(HPLC)(T), high purity , CAS No.55661-38-6

  • ≥98%(HPLC)(T)
Item Number
N159515
Grouped product items
SKUSizeAvailabilityPrice Qty
N159515-250mg
250mg
In stock
$58.90
N159515-1g
1g
Available within 4-8 weeks(?)
Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience!
$181.90
N159515-5g
5g
Available within 4-8 weeks(?)
Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience!
$816.90

DNA alkylator and cross-linking agent

View related series
Alkylating antitumor agents ureas

Basic Description

SynonymsNimustine hydrochloride|55661-38-6|Nimustine HCl|ACNU|Nidran|Nidran hydrochloride|Nimustine (hydrochloride)|52208-23-8|Nimustina clorhidrato|CS 439 HCl|Nimustine hydrochloride [JAN]|NSC-245,382|DFR965WKBU|CHEBI:7576|3-((4-Amino-2-methyl-5-pyrimidinyl)meth
Specifications & Purity≥98%(HPLC)(T)
Biochemical and Physiological MechanismsDNA alkylator and cross-linking agent. Antineoplastic agent. Active in vivo .
Shipped InNormal
NoteWherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour. Toxic, refer to SDS for further information. Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.

Associated Targets

RAPGEF4 Tchem Rap guanine nucleotide exchange factor 4 0 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

POLI Tchem DNA polymerase iota 0 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

TDP1 Tchem Tyrosyl-DNA phosphodiesterase 1 0 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

Names and Identifiers

IUPAC Name 3-[(4-amino-2-methylpyrimidin-5-yl)methyl]-1-(2-chloroethyl)-1-nitrosourea;hydrochloride
INCHI InChI=1S/C9H13ClN6O2.ClH/c1-6-12-4-7(8(11)14-6)5-13-9(17)16(15-18)3-2-10;/h4H,2-3,5H2,1H3,(H,13,17)(H2,11,12,14);1H
InChi Key KPMKNHGAPDCYLP-UHFFFAOYSA-N
Canonical SMILES CC1=NC=C(C(=N1)N)CNC(=O)N(CCCl)N=O.Cl
Isomeric SMILES CC1=NC=C(C(=N1)N)CNC(=O)N(CCCl)N=O.Cl
RTECS YR8450000
PubChem CID 91657
Molecular Weight 309.15
Reaxy-Rn 4220350

Certificates

Certificate of Analysis(COA)

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Chemical and Physical Properties

SolubilitySoluble in Methanol; Insoluble in Benzene,Ether,Chloroform
Sensitivitylight sensitive
Melt Point(°C)186°C(lit.)

Safety and Hazards(GHS)

Pictogram(s) GHS06
Signal Danger
Hazard Statements

H301:Toxic if swallowed

Precautionary Statements

P321:Specific treatment (see ... on this label).

P405:Store locked up.

P501:Dispose of contents/container to ...

P264:Wash hands [and …] thoroughly after handling.

P270:Do not eat, drink or smoke when using this product.

P330:Rinse mouth.

P301+P316:IF SWALLOWED: Get emergency medical help immediately.

RTECS YR8450000
Reaxy-Rn 4220350
Merck Index 6553

Related Documents

Solution Calculators