NQDI 1 - 97%, high purity , CAS No.175026-96-7

Item Number

N288303

• Synonyms: 2,7-Dihydro-2,7-dioxo-3H-naphtho[1,2,3-de]quinoline-1-carboxylic acid ethyl ester; ethyl 2,7-dioxo-3,7-dihydro-2H-naphtho[1,2,3-de]quinoline-1-carboxylate;NQDI-1
• Specifications & Purity: ≥97%
• Biochemical and Physiological Mechanisms: Selective inhibitor of apoptosis signal-regulating kinase 1 (ASK1, MAP3K5) (IC50= 3μM, Ki= 500 nM).NQDI-1 is an inhibitor of apoptosis signal-regulating kinase (ASK1), Ki = 500 nM. NQDI-1 shows little or no inhibitory activity against Aurora A or ROCK kin
• Storage Temp: Store at -20°C
• Shipped In: Ice chest + Ice pads

Product Description

Product Application：

NQDI-1 was used to study LPS-induced activation and role of ASK1 and p38 in anti-inflammatory cytokine production by macrophages.