NRX-252262 - 10mM in DMSO, high purity , CAS No.2438637-61-5(DMSO)

  • 10mM in DMSO
Item Number
N655065
Grouped product items
SKUSizeAvailabilityPrice Qty
N655065-1ml
1ml
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$420.90

Basic Description

Specifications & Purity10mM in DMSO
Biochemical and Physiological MechanismsNRX-252262 is a potent enhancer of the interaction between β-Catenin , and its cognate E3 ligase , SCF β-TrCP , induces mutant β-catenin degradation, with an EC 50 of 3.8 nM.
Storage TempStore at -80°C
Shipped InIce chest + Ice pads
Product Description

NRX-252262 is a potent enhancer of the interaction between β-Catenin , and its cognate E3 ligase , SCF β-TrCP , induces mutant β-catenin degradation, with an EC 50 of 3.8 nM

In Vitro

NRX-252262 (35 μM) causes S33E/S37A mutant β-catenin degradation in cells. MCE has not independently confirmed the accuracy of these methods. They are for reference only.

IC50& Target:EC50: 3.8 nM (β-Catenin-SCF β-TrCP )

Names and Identifiers

Canonical SMILES COC1=C(C=C2CN(CC2=C1)C(=O)C3=C(C=C(NC3=O)C(F)(F)F)SC4=C(C=CC=C4Cl)Cl)OC
Molecular Weight 545.36

Certificates

Certificate of Analysis(COA)

Enter Lot Number to search for COA:

Related Documents

Solution Calculators