NS13001 , CAS No.1063331-94-1, Activator of K Ca2.2;Activator of K Ca2.3

Item Number

N412979

Grouped product items
SKU	Size	Availability	Price
N412979-5mg	5mg	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$129.90
N412979-10mg	10mg	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$199.90
N412979-25mg	25mg	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$379.90
N412979-50mg	50mg	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$569.90
N412979-100mg	100mg	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$879.90
N412979-250mg	250mg	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$1,799.90

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Basic Description

Synonyms	1063331-94-1\|ns13001\|N-(4-chlorophenyl)-2-(3,5-dimethyl-1H-pyrazol-1-yl)-9-methyl-9H-purin-6-amine\|N-(4-chlorophenyl)-2-(3,5-dimethylpyrazol-1-yl)-9-methylpurin-6-amine\|DVQOPNIPUIOXHU-UHFFFAOYSA-N\|NS-13001\|SCHEMBL183176\|GTPL9316\|BCP15598\|EX-A4859\|MFCD2609
Specifications & Purity	97%
Storage Temp	Store at -20°C
Shipped In	Ice chest + Ice pads
Grade	Moligand™
Action Type	ACTIVATOR
Mechanism of action	Activator of K Ca2.2;Activator of K Ca2.3
Product Description	Information NS13001 is a potent, selective, orally active allosteric positive modulator of SK channels (small conductance calcium-activated potassium channels) with EC50 of 1.8 μM and 0.14 μM for SK2 and SK3, respectively.

Associated Targets

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

Names and Identifiers

IUPAC Name	N-(4-chlorophenyl)-2-(3,5-dimethylpyrazol-1-yl)-9-methylpurin-6-amine
INCHI	InChI=1S/C17H16ClN7/c1-10-8-11(2)25(23-10)17-21-15(14-16(22-17)24(3)9-19-14)20-13-6-4-12(18)5-7-13/h4-9H,1-3H3,(H,20,21,22)
InChi Key	DVQOPNIPUIOXHU-UHFFFAOYSA-N
Canonical SMILES	CC1=CC(=NN1C2=NC(=C3C(=N2)N(C=N3)C)NC4=CC=C(C=C4)Cl)C
Isomeric SMILES	CC1=CC(=NN1C2=NC(=C3C(=N2)N(C=N3)C)NC4=CC=C(C=C4)Cl)C
Alternate CAS	1063331-94-1
PubChem CID	44472568
MeSH Entry Terms	4-(chlorophenyl)-(2-(3,5-dimethylpyrazol-1-yl)-9-methyl-9H-purin-6-yl)amine;NS13001
Molecular Weight	353.8

Certificates

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12 results found

Lot Number	Certificate Type	Date	Item
B2421635	Certificate of Analysis	Jan 11, 2024	N412979
B2421636	Certificate of Analysis	Jan 11, 2024	N412979
B2421637	Certificate of Analysis	Jan 11, 2024	N412979
B2421638	Certificate of Analysis	Jan 11, 2024	N412979
B2421639	Certificate of Analysis	Jan 11, 2024	N412979
B2421640	Certificate of Analysis	Jan 11, 2024	N412979
B2421641	Certificate of Analysis	Jan 11, 2024	N412979
B2421642	Certificate of Analysis	Jan 11, 2024	N412979
B2421643	Certificate of Analysis	Jan 11, 2024	N412979
B2421644	Certificate of Analysis	Jan 11, 2024	N412979
B2421645	Certificate of Analysis	Jan 11, 2024	N412979
B2421651	Certificate of Analysis	Jan 11, 2024	N412979

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Basic Description