NV03 is a potent and selective antagonist of UHRF1 (Ubiquitin-like with PHD and RING finger domains 1)- H3K9me3 interaction by binding to UHRF1 tandem tudor domain, with a K d of 2.4 μM. NV03 has anticancer activity.
Storage Temp
Store at 2-8°C,Protected from light,Desiccated
Shipped In
Wet ice
Product Description
NV03 is a potent and selective antagonist of UHRF1 (Ubiquitin-like with PHD and RING finger domains 1)- H3K9me3 interaction by binding to UHRF1 tandem tudor domain, with a K d of 2.4 μM. NV03 has anticancer activity
Form:Solid
IC50& Target:UHRF1, H3K9me3
Names and Identifiers
Canonical SMILES
O=C1N(CC(NCCCN(CC)CC)=O)N=C(C)N2C1=C(C)C3=C2C=CS3
Molecular Weight
389.51
Certificates
Certificate of Analysis(COA)
Enter Lot Number to search for COA:
Chemical and Physical Properties
Solubility
DMSO : 33.33 mg/mL (85.57 mM; ultrasonic and warming and heat to 60°C)
