JavaScript seems to be disabled in your browser. For the best experience on our site, be sure to turn on Javascript in your browser.

྾

NYX-2925 , CAS No.N612447, Allosteric modulator of GluN2A

Item Number

N612447

Grouped product items
SKU	Size	Availability	Price	Qty
N612447-5mg	5mg	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$1,090.90
N612447-25mg	25mg	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$3,814.90

View related series

Basic Description

Synonyms	NYX-2925\|X062KF5ZV3\|UNII-X062KF5ZV3\|(2S,3R)-3-Hydroxy-2-((R)-5-isobutyryl-1-oxo-2,5-diazaspiro(3.4)octan-2yl)butanamide\|2012536-16-0\|2,5-Diazaspiro(3.4)octane-2-acetamide, alpha-((1R)-1-hydroxyethyl)-5-(2-methyl-1-oxopropyl)-1-oxo-, (alphaS,4R)-\|CHEMBL509
Grade	Moligand™
Action Type	ALLOSTERIC MODULATOR
Mechanism of action	Allosteric modulator of GluN2A

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

IUPAC Name	(2S,3R)-3-hydroxy-2-[(4R)-5-(2-methylpropanoyl)-3-oxo-2,5-diazaspiro[3.4]octan-2-yl]butanamide
INCHI	InChI=1S/C14H23N3O4/c1-8(2)12(20)17-6-4-5-14(17)7-16(13(14)21)10(9(3)18)11(15)19/h8-10,18H,4-7H2,1-3H3,(H2,15,19)/t9-,10+,14-/m1/s1
InChi Key	NFXPEHLDVKVVKA-ISTVAULSSA-N
Canonical SMILES	CC(C(=O)N1CCC[C@@]21CN(C2=O)[C@H](C(=O)N)[C@H](O)C)C
Isomeric SMILES	C[C@H]([C@@H](C(=O)N)N1C[C@@]2(C1=O)CCCN2C(=O)C(C)C)O
PubChem CID	122594417

PubChem CID	122594417

Enter Lot Number to search for COA:

1. Khan MA, Houck DR, Gross AL, Zhang XL, Cearley C, Madsen TM, Kroes RA, Stanton PK, Burgdorf J, Moskal JR. (2018) NYX-2925 Is a Novel NMDA Receptor-Specific Spirocyclic-β-Lactam That Modulates Synaptic Plasticity Processes Associated with Learning and Memory.. Int J Neuropsychopharmacol, 21 (3): (242-254). [PMID:29099938]

Determine the necessary mass, volume, or concentration for preparing a solution.

Determine the dilution needed to prepare a stock solution.