Determine the necessary mass, volume, or concentration for preparing a solution.
Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) |
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SKU | Size | Availability | Price | Qty |
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A129120-1g | 1g | Available within 4-8 weeks(?) Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience! | $19.90 | |
A129120-5g | 5g | Available within 4-8 weeks(?) Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience! | $74.90 | |
A129120-25g | 25g | Available within 4-8 weeks(?) Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience! | $226.90 | |
A129120-100g | 100g | Available within 4-8 weeks(?) Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience! | $813.90 | |
A129120-500g | 500g | Available within 4-8 weeks(?) Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience! | $3,662.90 |
L-Carnitine ( ab142499 ) derivative that enables CoA function. Antioxidant.
Synonyms | Acetyl-L-carnitine hydrochloride|o-Acetyl-L-carnitine hydrochloride|5080-50-2|O-Acetyl-L-carnitine HCl|Acetylcarnitine chloride|acetyl l-carnitine hydrochloride|UNII-NDW10MX58T|Acetylcarnitine L-form HCl|Acetylcarnitine hydrochloride|NDW10MX58T|Nicetile|A |
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Specifications & Purity | ≥99% |
Biochemical and Physiological Mechanisms | Enables CoA function. Lowers oxidative stress marker levels. Improves mitochondrial function. Blood-brain barrier permeable. Exhibits antidepressant, neuroprotective, analgesic and antinociceptive activities in vivo . |
Storage Temp | Store at 2-8°C,Argon charged |
Shipped In | Wet ice |
Note | Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour. Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details. |
Product Description | Endogenous mitochondrial metabolite that transports acetyl groups across the mitochondrial membrane. Exogenous acetylcarnitine enhances mitochondrial function in aged rats. As an acetate donor to coenzyme A, it increases the central and peripheral acetylcholine synthesis and function. Acetylcarnitine has antinociceptive activity that may be mediated by enhanced activity of muscarinic cholinergic receptors or mGlu2 glutamate receptors. |
Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) |
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IUPAC Name | [(2R)-2-acetyloxy-3-carboxypropyl]-trimethylazanium;chloride |
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INCHI | InChI=1S/C9H17NO4.ClH/c1-7(11)14-8(5-9(12)13)6-10(2,3)4;/h8H,5-6H2,1-4H3;1H/t8-;/m1./s1 |
InChi Key | JATPLOXBFFRHDN-DDWIOCJRSA-N |
Canonical SMILES | CC(=O)OC(CC(=O)O)C[N+](C)(C)C.[Cl-] |
Isomeric SMILES | CC(=O)O[C@H](CC(=O)O)C[N+](C)(C)C.[Cl-] |
WGK Germany | 3 |
PubChem CID | 2733928 |
Molecular Weight | 239.7 |
Beilstein | 4340103 |
Reaxy-Rn | 11461033 |
Enter Lot Number to search for COA:
To view the certificate results,please click on a Lot number.For Lot numbers from past orders,please use our order status section
Lot Number | Certificate Type | Date | Item |
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I2215088 | Certificate of Analysis | Jun 23, 2022 | A129120 |
I2215096 | Certificate of Analysis | Jun 23, 2022 | A129120 |
I2219423 | Certificate of Analysis | Jun 23, 2022 | A129120 |
I2219424 | Certificate of Analysis | Jun 23, 2022 | A129120 |
I2219430 | Certificate of Analysis | Jun 23, 2022 | A129120 |
Solubility | Soluble in water (100 mg/ml), alcohol, and ethanol (10%). Insoluble in ether. |
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Sensitivity | Hygroscopic |
Specific Rotation[α] | -28° (C=1,H2O) |
Melt Point(°C) | 194℃ |
Pictogram(s) | GHS07 |
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Signal | Warning |
Hazard Statements | H315:Causes skin irritation H319:Causes serious eye irritation H335:May cause respiratory irritation |
Precautionary Statements | P261:Avoid breathing dust/fume/gas/mist/vapors/spray. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses if present and easy to do - continue rinsing. P280:Wear protective gloves/protective clothing/eye protection/face protection. P302+P352:IF ON SKIN: wash with plenty of water. P321:Specific treatment (see ... on this label). P405:Store locked up. P501:Dispose of contents/container to ... P264:Wash hands [and …] thoroughly after handling. P271:Use only outdoors or in a well-ventilated area. P304+P340:IF INHALED: Remove person to fresh air and keep comfortable for breathing. P403+P233:Store in a well-ventilated place. Keep container tightly closed. P362+P364:Take off contaminated clothing and wash it before reuse. P264+P265:Wash hands [and …] thoroughly after handling. Do not touch eyes. P337+P317:If eye irritation persists: Get medical help. P332+P317:If skin irritation occurs: Get medical help. P319:Get medical help if you feel unwell. |
WGK Germany | 3 |
Reaxy-Rn | 11461033 |
Merck Index | 84 |