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O-Acetyl-L-carnitine hydrochloride - 99%, high purity , CAS No.5080-50-2

  • ≥99%
Item Number
A129120
Grouped product items
SKUSizeAvailabilityPrice Qty
A129120-1g
1g
Available within 4-8 weeks(?)
Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience!
$19.90
A129120-5g
5g
Available within 4-8 weeks(?)
Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience!
$74.90
A129120-25g
25g
Available within 4-8 weeks(?)
Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience!
$226.90
A129120-100g
100g
Available within 4-8 weeks(?)
Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience!
$813.90
A129120-500g
500g
Available within 4-8 weeks(?)
Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience!
$3,662.90

L-Carnitine ( ab142499 ) derivative that enables CoA function. Antioxidant.

View related series
Chemical Biology Peptide chemistry

Basic Description

SynonymsAcetyl-L-carnitine hydrochloride|o-Acetyl-L-carnitine hydrochloride|5080-50-2|O-Acetyl-L-carnitine HCl|Acetylcarnitine chloride|acetyl l-carnitine hydrochloride|UNII-NDW10MX58T|Acetylcarnitine L-form HCl|Acetylcarnitine hydrochloride|NDW10MX58T|Nicetile|A
Specifications & Purity≥99%
Biochemical and Physiological MechanismsEnables CoA function. Lowers oxidative stress marker levels. Improves mitochondrial function. Blood-brain barrier permeable. Exhibits antidepressant, neuroprotective, analgesic and antinociceptive activities in vivo .
Storage TempStore at 2-8°C,Argon charged
Shipped InWet ice
NoteWherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour. Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
Product Description

Endogenous mitochondrial metabolite that transports acetyl groups across the mitochondrial membrane. Exogenous acetylcarnitine enhances mitochondrial function in aged rats. As an acetate donor to coenzyme A, it increases the central and peripheral acetylcholine synthesis and function. Acetylcarnitine has antinociceptive activity that may be mediated by enhanced activity of muscarinic cholinergic receptors or mGlu2 glutamate receptors.
A cholinergic agonist that stimulates neuronal response to serotonin and acetylcholine.

Associated Targets

TARDBP Tchem TAR DNA-binding protein 43 0 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

Names and Identifiers

IUPAC Name [(2R)-2-acetyloxy-3-carboxypropyl]-trimethylazanium;chloride
INCHI InChI=1S/C9H17NO4.ClH/c1-7(11)14-8(5-9(12)13)6-10(2,3)4;/h8H,5-6H2,1-4H3;1H/t8-;/m1./s1
InChi Key JATPLOXBFFRHDN-DDWIOCJRSA-N
Canonical SMILES CC(=O)OC(CC(=O)O)C[N+](C)(C)C.[Cl-]
Isomeric SMILES CC(=O)O[C@H](CC(=O)O)C[N+](C)(C)C.[Cl-]
WGK Germany 3
PubChem CID 2733928
Molecular Weight 239.7
Beilstein 4340103
Reaxy-Rn 11461033

Certificates

Certificate of Analysis(COA)

Enter Lot Number to search for COA:

To view the certificate results,please click on a Lot number.For Lot numbers from past orders,please use our order status section

5 results found

Lot NumberCertificate TypeDateItem
I2215088Certificate of AnalysisJun 23, 2022 A129120
I2215096Certificate of AnalysisJun 23, 2022 A129120
I2219423Certificate of AnalysisJun 23, 2022 A129120
I2219424Certificate of AnalysisJun 23, 2022 A129120
I2219430Certificate of AnalysisJun 23, 2022 A129120

Chemical and Physical Properties

SolubilitySoluble in water (100 mg/ml), alcohol, and ethanol (10%). Insoluble in ether.
SensitivityHygroscopic
Specific Rotation[α]-28° (C=1,H2O)
Melt Point(°C)194℃

Safety and Hazards(GHS)

Pictogram(s) GHS07
Signal Warning
Hazard Statements

H315:Causes skin irritation

H319:Causes serious eye irritation

H335:May cause respiratory irritation

Precautionary Statements

P261:Avoid breathing dust/fume/gas/mist/vapors/spray.

P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses if present and easy to do - continue rinsing.

P280:Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352:IF ON SKIN: wash with plenty of water.

P321:Specific treatment (see ... on this label).

P405:Store locked up.

P501:Dispose of contents/container to ...

P264:Wash hands [and …] thoroughly after handling.

P271:Use only outdoors or in a well-ventilated area.

P304+P340:IF INHALED: Remove person to fresh air and keep comfortable for breathing.

P403+P233:Store in a well-ventilated place. Keep container tightly closed.

P362+P364:Take off contaminated clothing and wash it before reuse.

P264+P265:Wash hands [and …] thoroughly after handling. Do not touch eyes.

P337+P317:If eye irritation persists: Get medical help.

P332+P317:If skin irritation occurs: Get medical help.

P319:Get medical help if you feel unwell.

WGK Germany 3
Reaxy-Rn 11461033
Merck Index 84

Related Documents

Solution Calculators