O6BTG-octylglucoside is a potent O 6 -methylguanine-DNAmethyl-transferase ( MGMT ) inhibitor, with IC 50 s of 32 nM in vitro (cell extracts) and 10 nM in HeLa S3 cells.
In Vitro
O6BTG-octylglucoside is a potent and non-toxic MGMT inhibitor, with IC 50 s of 32 nM in vitro (cell extracts) and 10 nM in HeLa S3 cells. MCE has not independently confirmed the accuracy of these methods. They are for reference only.