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Oleuropein - analytical standard，≥98%(HPLC), high purity , CAS No.32619-42-4, Agonist of TAS2R8

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Oleuropein - analytical standard，≥98%(HPLC), high purity , CAS No.32619-42-4, Agonist of TAS2R8

analytical standard
Moligand™
≥98%(HPLC)

CAS#: 32619-42-4
Formula: C₂₅H₃₂O₁₃
Molecular Weight: 540.51
EC Number: 251-129-6
PubChem CID: 5281544

Item Number

O101532

Grouped product items
SKU	Size	Availability	Price	Qty
O101532-20mg	20mg	Available within 4-8 weeks(?) Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience!	$275.90

View related series

TAS2R8 Agonist

Basic Description

Synonyms	Oleuropein\|32619-42-4\|Oleoeuropein\|oleoeuropeine\|2-(3,4-Dihydroxyphenyl)ethyl (2S-(2alpha,3E,4beta))-3-ethylidene-2-(beta-D-glucopyranosyloxy)-3,4-dihydro-5-(methoxycarbonyl)-2H-pyran-4-acetate\|2O4553545L\|methyl (4S,5E,6S)-4-[2-[2-(3,4-dihydroxyphenyl)eth
Specifications & Purity	Moligand™, analytical standard, ≥98%(HPLC)
Biochemical and Physiological Mechanisms	Oleuropein, found in olive leaves and oil, exerts antioxidant, anti-inflammatory and anti-atherogenic effects through direct inhibition of PPARγ transcriptional activity. Oleuropein induces apoptosis in breast cancer cells via the p53-dependent pathway an
Storage Temp	Store at 2-8°C,Argon charged
Shipped In	Wet ice
Grade	analytical standard, Moligand™
Action Type	AGONIST
Mechanism of action	Agonist of TAS2R8

Associated Targets

HDAC6 Tclin Histone deacetylase 6 0 Activities

Discover Target: HDAC6

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

TAS2R8 Tchem Taste receptor type 2 member 8 0 Activities

Discover Target: TAS2R8

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

ALOX5 Tclin Arachidonate 5-lipoxygenase 0 Activities

Discover Target: ALOX5

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

Names and Identifiers

IUPAC Name	methyl (4S,5E,6S)-4-[2-[2-(3,4-dihydroxyphenyl)ethoxy]-2-oxoethyl]-5-ethylidene-6-[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy-4H-pyran-3-carboxylate
INCHI	InChI=1S/C25H32O13/c1-3-13-14(9-19(29)35-7-6-12-4-5-16(27)17(28)8-12)15(23(33)34-2)11-36-24(13)38-25-22(32)21(31)20(30)18(10-26)37-25/h3-5,8,11,14,18,20-22,24-28,30-32H,6-7,9-10H2,1-2H3/b13-3+/t14-,18+,20+,21-,22+,24-,25-/m0/s1
InChi Key	RFWGABANNQMHMZ-ZCHJGGQASA-N
Canonical SMILES	CC=C1C(C(=COC1OC2C(C(C(C(O2)CO)O)O)O)C(=O)OC)CC(=O)OCCC3=CC(=C(C=C3)O)O
Isomeric SMILES	C/C=C/1\[C@@H](C(=CO[C@H]1O[C@H]2[C@@H]([C@H]([C@@H]([C@H](O2)CO)O)O)O)C(=O)OC)CC(=O)OCCC3=CC(=C(C=C3)O)O
WGK Germany	3
PubChem CID	5281544
Molecular Weight	540.51

Database links

CAS Registry No.	32619-42-4
PubChem CID	5281544
ChEMBL Ligand	CHEMBL1911053
ChEBI	CHEBI:7747
Wikipedia	Oleuropein
Antibiotic DB	707

Certificates

Certificate of Analysis(COA)

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3 results found

Lot Number	Certificate Type	Date	Item
J2213946	Certificate of Analysis	Jul 04, 2024	O101532
G23151137	Certificate of Analysis	May 08, 2023	O101532
E2305083	Certificate of Analysis	Jul 14, 2022	O101532

Chemical and Physical Properties

Solubility	Soluble in water, acetone, ethanol, pyridine, glacial acetic acid , 5% aq NaOH, dioxane, butano, ethyl acetate, butyl acetate, DMF (50 mg/ml), and methanol. Insoluble in ether, chloroform, petr ether, benzene, and carbon tetrachloride.
Sensitivity	Hygroscopic
Specific Rotation[α]	-165° (C=0.5,EtOH)
Melt Point(°C)	89 °C

Safety and Hazards(GHS)

WGK Germany	3
Merck Index	6830

Alternative Products

References

1. Bisignano G, Tomaino A, Lo Cascio R, Crisafi G, Uccella N, Saija A. (1999) On the in-vitro antimicrobial activity of oleuropein and hydroxytyrosol.. J Pharm Pharmacol, 51 (8): (971-4). [PMID:10504039]
2. Omar SH. (2010) Oleuropein in olive and its pharmacological effects.. Sci Pharm, 78 (2): (133-54). [PMID:21179340]

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