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Oligomycin A from Streptomyces diastatochromogenes - ≥97%, high purity , CAS No.579-13-5

≥97%

CAS#: 579-13-5
Formula: C₄₅H₇₄O₁₁
Molecular Weight: 791.06
Beilstein Registry Number: 5702132
EC Number: 209-437-3
MDL number: MFCD00065705
PubChem CID: 5281899

Item Number

O102388

Grouped product items
SKU	Size	Availability	Price	Qty
O102388-5mg	5mg	Available within 4-8 weeks(?) Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience!	$307.90
O102388-25mg	25mg	Available within 4-8 weeks(?) Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience!	$990.90

Discover Oligomycin A from Streptomyces diastatochromogenes by Aladdin Scientific in ≥97% for only $307.90. Available - in Ligands at Aladdin Scientific. Macrolide antibiotic. ATP synthase inhibitor. Tags: .

Basic Description

Synonyms	MCH 32
Specifications & Purity	≥97%
Storage Temp	Store at -20°C
Shipped In	Dry ice
Product Description	Oligomycin A inhibits ATP5 (mitochondrial ATPases, F1F0) bound to the cell membrane. This compound stimulates lysosome acidification due to shunting of membrane potential at a concentration of 1.5-3 μM. The compound has been observed to Induce apoptosis in a variety of cell types along with inducing a switch from the apoptotic to necrotic pathway. It also exhibits broad nematocidal, antifungal, and antitumor activities. Oligomycin A has caused dissipated mitochondrial membrane potential, decreased cytoplasmic ATP contents and disassembled metaphase II oocyte spindles when introduced to mouse oocytes. Oligomycin is used to inhibit membrane bount mitochondrial ATP synthase. It is used to inhibit sucrose synthesis and 14C translocation in sunflower leaves, to study antibiotic resistance, and to study carotid chemoreceptor responses to O2 and CO2 in the cat.

Names and Identifiers

IUPAC Name	(1S,4E,5'R,6R,6'R,7S,8R,10S,11S,12R,14S,15R,16S,18E,20E,22S,25R,27S,28R,29S)-22-ethyl-7,11,14,15-tetrahydroxy-6'-[(2S)-2-hydroxypropyl]-5',6,8,10,12,14,16,28,29-nonamethylspiro[2,26-dioxabicyclo[23.3.1]nonacosa-4,18,20-triene-27,2'-oxane]-3,9,13-trione
INCHI	InChI=1S/C45H74O11/c1-12-34-17-15-13-14-16-27(4)42(51)44(11,53)43(52)32(9)40(50)31(8)39(49)30(7)38(48)26(3)18-21-37(47)54-41-29(6)35(20-19-34)55-45(33(41)10)23-22-25(2)36(56-45)24-28(5)46/h13-15,17-18,21,25-36,38,40-42,46,48,50-51,53H,12,16,19-20,22-24H2,1-11H3/b14-13+,17-15+,21-18+/t25-,26-,27+,28+,29+,30-,31-,32-,33-,34-,35-,36-,38+,40+,41+,42-,44+,45-/m1/s1
InChi Key	MNULEGDCPYONBU-WMBHJXFZSA-N
Canonical SMILES	CCC1CCC2C(C(C(C3(O2)CCC(C(O3)CC(C)O)C)C)OC(=O)C=CC(C(C(C(=O)C(C(C(C(=O)C(C(C(CC=CC=C1)C)O)(C)O)C)O)C)C)O)C)C
Isomeric SMILES	CC[C@H]\1CC[C@@H]2[C@@H]([C@@H]([C@H]([C@@]3(O2)CC[C@H]([C@H](O3)C[C@H](C)O)C)C)OC(=O)/C=C/[C@H]([C@@H]([C@H](C(=O)[C@H]([C@@H]([C@H](C(=O)[C@@]([C@@H]([C@H](C/C=C/C=C1)C)O)(C)O)C)O)C)C)O)C)C
WGK Germany	3
RTECS	RK3328000
PubChem CID	5281899
Molecular Weight	791.06
Beilstein	5702132

Certificates

Certificate of Analysis(COA)

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Lot Number	Certificate Type	Date	Item
F2418104	Certificate of Analysis	Jun 28, 2024	O102388

Chemical and Physical Properties

Solubility	Soluble in DMSO (300 mg/ml), ethanol (200 mg/ml), acetone (800 mg/ml), glacial acetic acid (37.5 g/100ml) at 25 °C, water (2 mg/100ml) at 25 °C, ether (28 g/100ml) at 25 °C, and benzene (6 g/100ml) at 25 °C.

Safety and Hazards(GHS)

Pictogram(s)	GHS06, GHS08, GHS07
Signal	Danger
Hazard Statements	H301:Toxic if swallowed H302:Harmful if swallowed H370:Causes damage to organs
Precautionary Statements	P321:Specific treatment (see ... on this label). P405:Store locked up. P501:Dispose of contents/container to ... P264:Wash hands [and …] thoroughly after handling. P260:Do not breathe dust/fume/gas/mist/vapors/spray. P270:Do not eat, drink or smoke when using this product. P330:Rinse mouth. P301+P316:IF SWALLOWED: Get emergency medical help immediately. P301+P317:IF SWALLOWED: Get medical help. P308+P316:IF exposed or concerned: Get emergency medical help immediately.
WGK Germany	3
RTECS	RK3328000

References

1. Malik AU et al.. (2021) Deciphering the LRRK code: LRRK1 and LRRK2 phosphorylate distinct Rab proteins and are regulated by diverse mechanisms.. Biochem J, 478 (3): (553-578). [PMID:33459343]
2. Luciani A et al.. (2020) Impaired mitophagy links mitochondrial disease to epithelial stress in methylmalonyl-CoA mutase deficiency.. Nat Commun, 11 (970). [PMID:32080200]
3. Arthur Wang,Åsa V Keita,Van Phan,Catherine M McKay,Ida Schoultz,Joshua Lee,Michael P Murphy,Maria Fernando,Natalie Ronaghan,Dale Balce,Robin Yates,Michael Dicay,Paul L Beck,Wallace K MacNaughton,Johan D Söderholm,Derek M McKay. (2014-07-19) Targeting mitochondria-derived reactive oxygen species to reduce epithelial barrier dysfunction and colitis.. The American journal of pathology, 184 ((9)): (2516-2527). [PMID:25034594]
4. Pedram Kharaziha,Dimitris Chioureas,George Baltatzis,Pedro Fonseca,Patricia Rodriguez,Vladimir Gogvadze,Lena Lennartsson,Ann-Charlotte Björklund,Boris Zhivotovsky,Dan Grandér,Lars Egevad,Sten Nilsson,Theocharis Panaretakis. (2015-09-30) Sorafenib-induced defective autophagy promotes cell death by necroptosis.. Oncotarget, 6 ((35)): (37066-37082). [PMID:26416459]
5. Keshav Kooragayala,Norimoto Gotoh,Tiziana Cogliati,Jacob Nellissery,Talia R Kaden,Stephanie French,Robert Balaban,Wei Li,Raul Covian,Anand Swaroop. (2016-01-10) Quantification of Oxygen Consumption in Retina Ex Vivo Demonstrates Limited Reserve Capacity of Photoreceptor Mitochondria.. Investigative ophthalmology & visual science, 56 ((13)): (8428-8436). [PMID:26747773]
6. Björn-Philipp Diercks,Ralf Fliegert,Andreas H Guse. (2016-12-04) Mag-Fluo4 in T cells: Imaging of intra-organelle free Ca. Biochimica et biophysica acta, 1864 ((6)): (977-986). [PMID:27913206]
7. Yi Sak Kim,Hye-Mi Lee,Jin Kyung Kim,Chul-Su Yang,Tae Sung Kim,Mingyu Jung,Hyo Sun Jin,Sup Kim,Jichan Jang,Goo Taeg Oh,Jin-Man Kim,Eun-Kyeong Jo. (2017-03-10) PPAR-α Activation Mediates Innate Host Defense through Induction of TFEB and Lipid Catabolism.. Journal of immunology (Baltimore, Md. : 1950), 198 ((8)): (3283-3295). [PMID:28275133]
8. Christopher A Waker,Renee E Albers,Richard L Pye,Savannah R Doliboa,Christopher N Wyatt,Thomas L Brown,Debra A Mayes. (2017-03-25) AMPK Knockdown in Placental Labyrinthine Progenitor Cells Results in Restriction of Critical Energy Resources and Terminal Differentiation Failure.. Stem cells and development, 26 ((11)): (808-817). [PMID:28335680]
9. Stephanie A Zlatic,Alysia Vrailas-Mortimer,Avanti Gokhale,Lucas J Carey,Elizabeth Scott,Reid Burch,Mo. (2018-02-06) Rare Disease Mechanisms Identified by Genealogical Proteomics of Copper Homeostasis Mutant Pedigrees.. Cell systems, 6 ((3)): (368-380). [PMID:29397366]
10. Alban Ordureau,Joao A Paulo,Wei Zhang,Tim Ahfeldt,Jiuchun Zhang,Erin F Cohn,Zhonggang Hou,Jin-Mi Heo,Lee L Rubin,Sachdev S Sidhu,Steven P Gygi,J Wade Harper. (2018-04-17) Dynamics of PARKIN-Dependent Mitochondrial Ubiquitylation in Induced Neurons and Model Systems Revealed by Digital Snapshot Proteomics.. Molecular cell, 70 ((2)): (211-227). [PMID:29656925]
11. Juliane Hitzel,Eunjee Lee,Yi Zhang,Sofia Iris Bibli,Xiaogang Li,Sven Zukunft,Beatrice Pflüger,Jiong Hu,Christoph Schürmann,Andrea Estefania Vasconez,James A Oo,Adelheid Kratzer,Sandeep Kumar,Flávia Rezende,Ivana Josipovic,Dominique Thomas,Hector Giral,Yannick Schreiber,Gerd Geisslinger,Christian Fork,Xia Yang,Fragiska Sigala,Casey E Romanoski,Jens Kroll,Hanjoong Jo,Ulf Landmesser,Aldons J Lusis,Dmitry Namgaladze,Ingrid Fleming,Matthias S Leisegang,Jun Zhu,Ralf P Brandes. (2018-06-14) Oxidized phospholipids regulate amino acid metabolism through MTHFD2 to facilitate nucleotide release in endothelial cells.. Nature communications, 9 ((1)): (2292-2292). [PMID:29895827]
12. Cody A Cunningham,Suzanne Hoppins,Pamela J Fink. (2018-08-03) Cutting Edge: Glycolytic Metabolism and Mitochondrial Metabolism Are Uncoupled in Antigen-Activated CD8+ Recent Thymic Emigrants.. Journal of immunology (Baltimore, Md. : 1950), 201 ((6)): (1627-1632). [PMID:30068595]
13. Federico A Prestia,Pablo Galeano,Pamela V Martino Adami,Sonia Do Carmo,Eduardo M Castaño,A Claudio Cuello,Laura Morelli. (2018-10-26) Platelets Bioenergetics Screening Reflects the Impact of Brain Aβ Plaque Accumulation in a Rat Model of Alzheimer.. Neurochemical research, 44 ((6)): (1375-1386). [PMID:30357651]
14. Samuel E Weinberg,Benjamin D Singer,Elizabeth M Steinert,Carlos A Martinez,Manan M Mehta,Inmaculada Martínez-Reyes,Peng Gao,Kathryn A Helmin,Hiam Abdala-Valencia,Laura A Sena,Paul T Schumacker,Laurence A Turka,Navdeep S Chandel. (2019-01-11) Mitochondrial complex III is essential for suppressive function of regulatory T cells.. Nature, 565 ((7740)): (495-499). [PMID:30626970]
15. Lorna R Fiedler,Kathryn Chapman,Min Xie,Evie Maifoshie,Micaela Jenkins,Pelin Arabacilar Golforoush,Mohamed Bellahcene,Michela Noseda,Dörte Faust,Ashley Jarvis,Gary Newton,Marta Abreu Paiva,Mutsuo Harada,Daniel J Stuckey,Weihua Song,Josef Habib,Priyanka Narasimhan,Rehan Aqil,Devika Sanmugalingam,Robert Yan,Lorenzo Pavanello,Motoaki Sano,Sam C Wang,Robert D Sampson,Sunthar Kanayaganam,George E Taffet,Lloyd H Michael,Mark L Entman,Tse-Hua Tan,Sian E Harding,Caroline M R Low,Catherine Tralau-Stewart,Trevor Perrior,Michael D Schneider. (2019-03-12) MAP4K4 Inhibition Promotes Survival of Human Stem Cell-Derived Cardiomyocytes and Reduces Infarct Size In\xa0Vivo.. Cell stem cell, 24 ((4)): (579-591). [PMID:30853557]
16. Prashanti Patil,Micol Falabella,Amal Saeed,Dayeong Lee,Brett Kaufman,Sruti Shiva,Claudette St Croix,Ben Van Houten,Laura J Niedernhofer,Paul D Robbins,Joon Lee,Sowa Gwendolyn,Nam V Vo. (2019-04-20) Oxidative stress-induced senescence markedly increases disc cell bioenergetics.. Mechanisms of ageing and development, 180 (97-106). [PMID:31002926]
17. Trace Thome,Zachary R Salyers,Ravi A Kumar,Dongwoo Hahn,Fabian N Berru,Leonardo F Ferreira,Salvatore T Scali,Terence E Ryan. (2019-07-11) Uremic metabolites impair skeletal muscle mitochondrial energetics through disruption of the electron transport system and matrix dehydrogenase activity.. American journal of physiology. Cell physiology, 317 ((4)): (C701-C713). [PMID:31291144]
18. Yan Zhen,Hélène Spangenberg,Michael J Munson,Andreas Brech,Kay O Schink,Kia-Wee Tan,Vigdis Sørensen,Eva Maria Wenzel,Maja Radulovic,Nikolai Engedal,Anne Simonsen,Camilla Raiborg,Harald Stenmark. (2019-08-02) ESCRT-mediated phagophore sealing during mitophagy.. Autophagy, 16 ((5)): (826-841). [PMID:31366282]
19. Marco Tozzi,Jacob B Hansen,Ivana Novak. (2019-08-11) Pannexin-1 mediated ATP release in adipocytes is sensitive to glucose and insulin and modulates lipolysis and macrophage migration.. Acta physiologica (Oxford, England), 228 ((2)): (e13360-e13360). [PMID:31400255]
20. M Jacoupy,E Hamon-Keromen,A Ordureau,Z Erpapazoglou,F Coge,J-C Corvol,O Nosjean,C Mannoury la Cour,M J Millan,J A Boutin,J W Harper,A Brice,D Guedin,C A Gautier,O Corti. (2019-08-16) The PINK1 kinase-driven ubiquitin ligase Parkin promotes mitochondrial protein import through the presequence pathway in living cells.. Scientific reports, 9 ((1)): (11829-11829). [PMID:31413265]
21. James Hamilton,Tatiana Brustovetsky,Nickolay Brustovetsky. (2019-08-17) Mutant huntingtin fails to directly impair brain mitochondria.. Journal of neurochemistry, 151 ((6)): (716-731). [PMID:31418857]
22. Benjamin Gottschalk,Christiane Klec,Gerd Leitinger,Eva Bernhart,René Rost,Helmut Bischof,Corina T Madreiter-Sokolowski,Snježana Radulović,Emrah Eroglu,Wolfgang Sattler,Markus Waldeck-Weiermair,Roland Malli,Wolfgang F Graier. (2019-08-21) MICU1 controls cristae junction and spatially anchors mitochondrial Ca2+ uniporter complex.. Nature communications, 10 ((1)): (3732-3732). [PMID:31427612]
23. Kaifeng Niu,Hongbo Fang,Zixiang Chen,Yuqi Zhu,Qunsong Tan,Di Wei,Yueyang Li,Adayabalam S Balajee,Yongliang Zhao. (2019-08-23) USP33 deubiquitinates PRKN/parkin and antagonizes its role in mitophagy.. Autophagy, 16 ((4)): (724-734). [PMID:31432739]
24. Marta Codrich,Marina Comelli,Matilde Clarissa Malfatti,Catia Mio,Dilara Ayyildiz,Chi Zhang,Mark R Kelley,Giovanni Terrosu,Carlo E M Pucillo,Gianluca Tell. (2019-08-27) Inhibition of APE1-endonuclease activity affects cell metabolism in colon cancer cells via a p53-dependent pathway.. DNA repair, 82 (102675-102675). [PMID:31450087]
25. Yuexi Gu,Yakubu Princely Abudu,Suresh Kumar,Bhawana Bissa,Seong Won Choi,Jingyue Jia,Michael Lazarou,Eeva-Liisa Eskelinen,Terje Johansen,Vojo Deretic. (2019-10-19) Mammalian Atg8 proteins regulate lysosome and autolysosome biogenesis through SNAREs.. The EMBO journal, 38 ((22)): (e101994-e101994). [PMID:31625181]
26. Ashwini Hinge,Jingyi He,James Bartram,Jose Javier,Juying Xu,Ellen Fjellman,Hiromi Sesaki,Tingyu Li,Jie Yu,Mark Wunderlich,James Mulloy,Matthew Kofron,Nathan Salomonis,H Leighton Grimes,Marie-Dominique Filippi. (2020-02-16) Asymmetrically Segregated Mitochondria Provide Cellular Memory of Hematopoietic Stem Cell Replicative History and Drive HSC Attrition.. Cell stem cell, 26 ((3)): (420-430). [PMID:32059807]
27. Tomokazu Ohishi,Hikaru Abe,Chiharu Sakashita,Uzma Saqib,Mirza S Baig,Shun-Ichi Ohba,Hiroyuki Inoue,Takumi Watanabe,Masakatsu Shibasaki,Manabu Kawada. (2020-03-08) Inhibition of mitochondria ATP synthase suppresses prostate cancer growth through reduced insulin-like growth factor-1 secretion by prostate stromal cells.. International journal of cancer, 146 ((12)): (3474-3484). [PMID:32144767]
28. Léa Montégut,Pablo César Martínez-Basilio,Jorgelindo da Veiga Moreira,Laurent Schwartz,Mario Jolicoeur. (2020-04-17) Combining lipoic acid to methylene blue reduces the Warburg effect in CHO cells: From TCA cycle activation to enhancing monoclonal antibody production.. PloS one, 15 ((4)): (e0231770-e0231770). [PMID:32298377]
29. Jeffrey C Davis,Tiago C Alves,Aharon Helman,Jonathan C Chen,Jennifer H Kenty,Rebecca L Cardone,David R Liu,Richard G Kibbey,Douglas A Melton. (2020-05-14) Glucose Response by Stem Cell-Derived β Cells In\xa0Vitro Is Inhibited by a Bottleneck in Glycolysis.. Cell reports, 31 ((6)): (107623-107623). [PMID:32402282]
30. Eran Mick,Denis V Titov,Owen S Skinner,Rohit Sharma,Alexis A Jourdain,Vamsi K Mootha. (2020-05-29) Distinct mitochondrial defects trigger the integrated stress response depending on the metabolic state of the cell.. eLife, 9 [PMID:32463360]
31. Ayon Ibrahim,Nora Yucel,Boa Kim,Zoltan Arany. (2020-06-11) Local Mitochondrial ATP Production Regulates Endothelial Fatty Acid Uptake and Transport.. Cell metabolism, 32 ((2)): (309-319). [PMID:32521232]
32. John Quiroga,Pablo Alarcón,Carolina Manosalva,Anja Taubert,Carlos Hermosilla,María Angélica Hidalgo,María Daniella Carretta,Rafael Agustín Burgos. (2020-06-17) Glycolysis and mitochondrial function regulate the radical oxygen species production induced by platelet-activating factor in bovine polymorphonuclear leukocytes.. Veterinary immunology and immunopathology, 226 (110074-110074). [PMID:32540687]
33. Harry J Hurley,Hannah Dewald,Zachary S Rothkopf,Sukhwinder Singh,Frank Jenkins,Pratik Deb,Saurav De,Betsy J Barnes,Patricia Fitzgerald-Bocarsly. (2020-07-09) Frontline Science: AMPK regulates metabolic reprogramming necessary for interferon production in human plasmacytoid dendritic cells.. Journal of leukocyte biology, 109 ((2)): (299-308). [PMID:32640499]
34. Hamilton, et al.. (2020) Mutant huntingtin does not cross the mitochondrial outer membrane.. Human Molecular Genetics, 29 (2962-2975). [PMID:32821928]
35. Thomas Rauter,Maria R Depaoli,Helmut Bischof,Wolfgang F Graier,Roland Malli. (2020-10-29) Metabolic Profiling of Single Cancer Cells Using Mitochondrial ATP Probes.. STAR protocols, 1 ((2)): (100048-100048). [PMID:33111094]
36. Fangyuan Shao,Xueying Lyu,Kai Miao,Lisi Xie,Haitao Wang,Hao Xiao,Jie Li,Qiang Chen,Renbo Ding,Ping Chen,Fuqiang Xing,Xu Zhang,Guang-Hui Luo,Wenli Zhu,Gregory Cheng,Ng Wai Lon,Scott E Martin,Guanyu Wang,Guokai Chen,Yunlu Dai,Chu-Xia Deng. (2020-12-12) Enhanced Protein Damage Clearance Induces Broad Drug Resistance in Multitype of Cancers Revealed by an Evolution Drug-Resistant Model and Genome-Wide siRNA Screening.. Advanced science (Weinheim, Baden-Wurttemberg, Germany), 7 ((23)): (2001914-2001914). [PMID:33304752]
37. Jia Sun,Xiaozhong Huang,Chao Niu,Xuejiao Wang,Wanqian Li,Mengxue Liu,Ying Wang,Shuai Huang,Xixi Chen,Xiaokun Li,Yang Wang,Litai Jin,Jian Xiao,Weitao Cong. (2020-12-29) aFGF alleviates diabetic endothelial dysfunction by decreasing oxidative stress via Wnt/β-catenin-mediated upregulation of HXK2.. Redox biology, 39 (101811-101811). [PMID:33360774]
38. Karl Kochanowski,Timur Sander,Hannes Link,Jeremy Chang,Steven J Altschuler,Lani F Wu. (2021-01-21) Systematic alteration of in\xa0vitro metabolic environments reveals empirical growth relationships in cancer cell phenotypes.. Cell reports, 34 ((3)): (108647-108647). [PMID:33472066]
39. Mengqing Gao,Jin Wang,Sophie Rousseaux,Minjia Tan,Lulu Pan,Lijun Peng,Sisi Wang,Wenqian Xu,Jiayi Ren,Yuanfang Liu,Martin Spinck,Sophie Barral,Tao Wang,Florent Chuffart,Ekaterina Bourova-Flin,Denis Puthier,Sandrine Curtet,Lisa Bargier,Zhongyi Cheng,Heinz Neumann,Jian Li,Yingming Zhao,Jian-Qing Mi,Saadi Khochbin. (2021-07-29) Metabolically controlled histone H4K5 acylation/acetylation ratio drives BRD4 genomic distribution.. Cell reports, 36 ((4)): (109460-109460). [PMID:34320364]
40. Sarah Krantz,Young-Mee Kim,Shubhi Srivastava,Joseph W Leasure,Peter T Toth,Glenn Marsboom,Jalees Rehman. (2021-11-18) Mitophagy mediates metabolic reprogramming of induced pluripotent stem cells undergoing endothelial differentiation.. The Journal of biological chemistry, 297 ((6)): (101410-101410). [PMID:34785214]
41. Rukmini Mukherjee,Oishee Chakrabarti. (2016-01-09) Ubiquitin-mediated regulation of the E3 ligase GP78 by MGRN1 in trans affects mitochondrial homeostasis.. Journal of cell science, 129 ((4)): (757-773). [PMID:26743086]
42. Qin Hu,Anatol Manaenko,Hetao Bian,Zongduo Guo,Jun-Long Huang,Zhen-Ni Guo,Peng Yang,Jiping Tang,John H Zhang. (2017-05-13) Hyperbaric Oxygen Reduces Infarction Volume and Hemorrhagic Transformation Through ATP/NAD. Stroke, 48 ((6)): (1655-1664). [PMID:28495827]
43. Jennifer L Bays,Hannah K Campbell,Christy Heidema,Michael Sebbagh,Kris A DeMali. (2017-05-30) Linking E-cadherin mechanotransduction to cell metabolism through force-mediated activation of\xa0AMPK.. Nature cell biology, 19 ((6)): (724-731). [PMID:28553939]
44. Mei Yu,Yuhong Chen,Hu Zeng,Yongwei Zheng,Guoping Fu,Wen Zhu,Ulrich Broeckel,Praful Aggarwal,Amy Turner,Geoffrey Neale,Cliff Guy,Nan Zhu,Hongbo Chi,Renren Wen,Demin Wang. (2017-11-15) PLCγ-dependent mTOR signalling controls IL-7-mediated early B cell development.. Nature communications, 8 ((1)): (1457-1457). [PMID:29133930]
45. Jil Sander,Susanne V Schmidt,Branko Cirovic,Naomi McGovern,Olympia Papantonopoulou,Anna-Lena Hardt,Anna C Aschenbrenner,Christoph Kreer,Thomas Quast,Alexander M Xu,Lisa M Schmidleithner,Heidi Theis,Lan Do Thi Huong,Hermi Rizal Bin Sumatoh,Mario A R Lauterbach,Jonas Schulte-Schrepping,Patrick Günther,Jia Xue,Kevin Baßler,Thomas Ulas,Kathrin Klee,Natalie Katzmarski,Stefanie Herresthal,Wolfgang Krebs,Bianca Martin,Eicke Latz,Kristian Händler,Michael Kraut,Waldemar Kolanus,Marc Beyer,Christine S Falk,Bettina Wiegmann,Sven Burgdorf,Nicholas A Melosh,Evan W Newell,Florent Ginhoux,Andreas Schlitzer,Joachim L Schultze. (2017-12-21) Cellular Differentiation of Human Monocytes Is Regulated by Time-Dependent Interleukin-4 Signaling and the Transcriptional Regulator NCOR2.. Immunity, 47 ((6)): (1051-1066). [PMID:29262348]
46. Tal Yardeni,Raquel Fine,Yuvraj Joshi,Tal Gradus-Pery,Noga Kozer,Irit Reichenstein,Eran Yanowski,Shir Nevo,Hila Weiss-Tishler,Michal Eisenberg-Bord,Tal Shalit,Alexander Plotnikov,Haim M Barr,Eran Perlson,Eran Hornstein. (2018-01-10) High content image analysis reveals function of miR-124 upstream of Vimentin in regulating motor neuron mitochondria.. Scientific reports, 8 ((1)): (59-59). [PMID:29311649]
47. Azadeh Seidi,Linden S Muellner-Wong,Esther Rajendran,Edwin T Tjhin,Laura F Dagley,Vincent Yt Aw,Pierre Faou,Andrew I Webb,Christopher J Tonkin,Giel G van Dooren. (2018-09-12) Elucidating the mitochondrial proteome of Toxoplasma gondii reveals the presence of a divergent cytochrome c oxidase.. eLife, 7 [PMID:30204084]
48. Hufei Wang,Jiamin Chen,Megumi Suda,Yukie Yanagiba,Zuquan Weng,Rui-Sheng Wang. (2018-09-22) Acute inhalation co-exposure to 1,2-dichloropropane and dichloromethane cause liver damage by inhibiting mitochondrial respiration and defense ability in mice.. Journal of applied toxicology : JAT, 39 ((2)): (260-270). [PMID:30240022]
49. Eduardo Seiji Yamamoto,Jéssica Adriana Jesus,Adriana Bezerra-Souza,Márcia Dalastra Laurenti,Susan Pereira Ribeiro,Luiz Felipe Domingues Passero. (2018-12-21) Activity of Fenticonazole, Tioconazole and Nystatin on New World Leishmania Species.. Current topics in medicinal chemistry, 18 ((27)): (2338-2346). [PMID:30569856]
50. Qianqian Liu,Yang Sun,Zaiyi Fei,Zhibin Yang,Ke Duan,Jiaji Zi,Qinghua Cui,Min Yu,Wei Xiong. (2019-06-13) Leptin promotes fatty acid oxidation and OXPHOS via the c-Myc/PGC-1 pathway in cancer cells.. Acta biochimica et biophysica Sinica, 51 ((7)): (707-714). [PMID:31187140]
51. Romain Guièze,Vivian M Liu,Daniel Rosebrock,Alexis A Jourdain,María Hernández-Sánchez,Aina Martinez Zurita,Jing Sun,Elisa Ten Hacken,Kaitlyn Baranowski,Philip A Thompson,Jin-Mi Heo,Zachary Cartun,Ozan Aygün,J Bryan Iorgulescu,Wandi Zhang,Giulia Notarangelo,Dimitri Livitz,Shuqiang Li,Matthew S Davids,Anat Biran,Stacey M Fernandes,Jennifer R Brown,Ana Lako,Zoe B Ciantra,Matthew A Lawlor,Derin B Keskin,Namrata D Udeshi,William G Wierda,Kenneth J Livak,Anthony G Letai,Donna Neuberg,J Wade Harper,Steven A Carr,Federica Piccioni,Christopher J Ott,Ignaty Leshchiner,Cory M Johannessen,John Doench,Vamsi K Mootha,Gad Getz,Catherine J Wu. (2019-09-24) Mitochondrial Reprogramming Underlies Resistance to BCL-2 Inhibition in Lymphoid Malignancies.. Cancer cell, 36 ((4)): (369-384). [PMID:31543463]
52. Patrycja Michalska,Giammarco Tenti,Michelle Satriani,Angel Cores,María Teresa Ramos,Antonio G García,José Carlos Menéndez,Rafael León. (2019-11-07) Aza-CGP37157-lipoic hybrids designed as novel Nrf2-inducers and antioxidants exert neuroprotection against oxidative stress and show neuroinflammation inhibitory properties.. Drug development research, 81 ((3)): (283-294). [PMID:31693218]
53. Mario A Lauterbach,Jasmin E Hanke,Magdalini Serefidou,Matthew S J Mangan,Carl-Christian Kolbe,Timo Hess,Maximilian Rothe,Romina Kaiser,Florian Hoss,Jan Gehlen,Gudrun Engels,Maike Kreutzenbeck,Susanne V Schmidt,Anette Christ,Axel Imhof,Karsten Hiller,Eicke Latz. (2019-12-19) Toll-like Receptor Signaling Rewires Macrophage Metabolism and Promotes Histone Acetylation via ATP-Citrate Lyase.. Immunity, 51 ((6)): (997-1011). [PMID:31851905]
54. Daan M Panneman,Saskia B Wortmann,Charlotte A Haaxma,Peter M van Hasselt,Nicole I Wolf,Yvonne Hendriks,Benno Küsters,Sjenet van Emst-de Vries,Els van de Westerlo,Werner J H Koopman,Liesbeth Wintjes,Frans van den Brandt,Maaike de Vries,Dirk J Lefeber,Jan A M Smeitink,Richard J Rodenburg. (2020-01-21) Variants in NGLY1 lead to intellectual disability, myoclonus epilepsy, sensorimotor axonal polyneuropathy and mitochondrial dysfunction.. Clinical genetics, 97 ((4)): (556-566). [PMID:31957011]
55. Hironori Kato,Kohki Okabe,Masato Miyake,Kazuki Hattori,Tomohiro Fukaya,Kousuke Tanimoto,Shi Beini,Mariko Mizuguchi,Satoru Torii,Satoko Arakawa,Masaya Ono,Yusuke Saito,Takashi Sugiyama,Takashi Funatsu,Katsuaki Sato,Shigeomi Shimizu,Seiichi Oyadomari,Hidenori Ichijo,Hisae Kadowaki,Hideki Nishitoh. (2020-02-08) ER-resident sensor PERK is essential for mitochondrial thermogenesis in brown adipose tissue.. Life science alliance, 3 ((3)): [PMID:32029570]
56. Sas N Dijk,Margherita Protasoni,Marilena Elpidorou,Albert M Kroon,Jan-Willem Taanman. (2020-03-11) Mitochondria as target to inhibit proliferation and induce apoptosis of cancer cells: the effects of doxycycline and gemcitabine.. Scientific reports, 10 ((1)): (4363-4363). [PMID:32152409]
57. Dibyanti Mukherjee,Vivek Chander,Arun Bandyopadhyay. (2020-10-21) PARIS-DJ-1 Interaction Regulates Mitochondrial Functions in Cardiomyocytes, Which Is Critically Important in Cardiac Hypertrophy.. Molecular and cellular biology, 41 ((1)): [PMID:33077496]

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