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Olsalazine Sodium - ≥99%, high purity , CAS No.6054-98-4

2 Citations

≥99%

CAS#: 6054-98-4
Formula: C₁₄H₈N₂Na₂O₆
Molecular Weight: 346.2
MDL number: MFCD00013300
PubChem CID: 135413505
PubChem SID: 488202862

Item Number

O129450

Grouped product items
SKU	Size	Availability	Price
O129450-1g	1g	In stock	$18.90
O129450-5g	5g	In stock	$77.90
O129450-25g	25g	In stock	$351.90

Anti-inflammatory agent

View related series

Pharmaceutical ingredients

Basic Description

Synonyms	P17048 \| UNII-Y7JEW0XG7I \| Benzoic acid, 3,3'-azobis(6-hydroxy-, disodium salt \| SW219353-1 \| SW219659-1 \| 4,4'-Dihydroxyazobenzene-3,3'-dicarboxylic Acid Disodium Salt \| FT-0657732 \| HMS3264H09 \| Y7JEW0XG7I \| ZJEFYLVGGFISGT-UHFFFAOYSA-L \| 3,3'-azo-bis(6-
Specifications & Purity	≥99%
Storage Temp	Protected from light,Store at -20°C
Shipped In	Ice chest + Ice pads
Product Description	Olsalazine Sodium is a mesalamine dimer.Olsalazine Sodium is a anti-inflammatory prodrug, which consists of two 5-ASA moieties linked by an azo bond. An anti-inflammatory agent

Names and Identifiers

Pubchem Sid	488202862
Pubchem Sid Url	https://pubchem.ncbi.nlm.nih.gov/substance/488202862
IUPAC Name	disodium;2-carboxy-4-[(3-carboxy-4-oxidophenyl)diazenyl]phenolate
INCHI	InChI=1S/C14H10N2O6.2Na/c17-11-3-1-7(5-9(11)13(19)20)15-16-8-2-4-12(18)10(6-8)14(21)22;;/h1-6,17-18H,(H,19,20)(H,21,22);;/q;2*+1/p-2
InChi Key	ZJEFYLVGGFISGT-UHFFFAOYSA-L
Canonical SMILES	C1=CC(=C(C=C1N=NC2=CC(=C(C=C2)[O-])C(=O)O)C(=O)O)[O-].[Na+].[Na+]
Isomeric SMILES	C1=CC(=C(C=C1N=NC2=CC(=C(C=C2)[O-])C(=O)O)C(=O)O)[O-].[Na+].[Na+]
PubChem CID	135413505
Molecular Weight	346.2

Certificates

Certificate of Analysis(COA)

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10 results found

Lot Number	Certificate Type	Date	Item
J1822058	Certificate of Analysis	Jul 05, 2024	O129450
E2317931	Certificate of Analysis	Jan 04, 2023	O129450
E2317938	Certificate of Analysis	Jan 04, 2023	O129450
E2317964	Certificate of Analysis	Jan 04, 2023	O129450
E2317968	Certificate of Analysis	Jan 04, 2023	O129450
E2317969	Certificate of Analysis	Jan 04, 2023	O129450
E2317976	Certificate of Analysis	Jan 04, 2023	O129450
K2221162	Certificate of Analysis	Dec 06, 2022	O129450
K1827159	Certificate of Analysis	Oct 15, 2022	O129450
J1822057	Certificate of Analysis	Oct 15, 2022	O129450

Solubility

Soluble in water, and DMSO.

Sensitivity

light sensitive;Moisture sensitive

Melt Point(°C)

294 °C(dec.)

Safety and Hazards(GHS)

Pictogram(s)	GHS07
Signal	Warning
Hazard Statements	H315:Causes skin irritation H319:Causes serious eye irritation H335:May cause respiratory irritation
Precautionary Statements	P261:Avoid breathing dust/fume/gas/mist/vapors/spray. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses if present and easy to do - continue rinsing. P280:Wear protective gloves/protective clothing/eye protection/face protection. P302+P352:IF ON SKIN: wash with plenty of water. P321:Specific treatment (see ... on this label). P405:Store locked up. P501:Dispose of contents/container to ... P264:Wash hands [and …] thoroughly after handling. P271:Use only outdoors or in a well-ventilated area. P304+P340:IF INHALED: Remove person to fresh air and keep comfortable for breathing. P403+P233:Store in a well-ventilated place. Keep container tightly closed. P362+P364:Take off contaminated clothing and wash it before reuse. P264+P265:Wash hands [and …] thoroughly after handling. Do not touch eyes. P337+P317:If eye irritation persists: Get medical help. P332+P317:If skin irritation occurs: Get medical help. P319:Get medical help if you feel unwell.
Merck Index	6841

Citations of This Product

1. Jiaying Li, Yuji Pu, Sai Li, Bin He, Jianlin Chen. (2023) Orally Administrated Olsalazine-Loaded Multilayer Pectin/Chitosan/Alginate Composite Microspheres for Ulcerative Colitis Treatment. BIOMACROMOLECULES, 24 (5): (2250–2263). [PMID:37068182]
2. Qiqi Sun, Jun Chen, Quan Zhao, Ziyun He, Lei Tang, Yuji Pu, Bin He. (2023) Bio-adhesive and ROS-scavenging hydrogel microspheres for targeted ulcerative colitis therapy. INTERNATIONAL JOURNAL OF PHARMACEUTICS, 639 (122962). [PMID:37068716]

References

1. Jiaying Li, Yuji Pu, Sai Li, Bin He, Jianlin Chen. (2023) Orally Administrated Olsalazine-Loaded Multilayer Pectin/Chitosan/Alginate Composite Microspheres for Ulcerative Colitis Treatment. BIOMACROMOLECULES, 24 (5): (2250–2263). [PMID:37068182]
2. Qiqi Sun, Jun Chen, Quan Zhao, Ziyun He, Lei Tang, Yuji Pu, Bin He. (2023) Bio-adhesive and ROS-scavenging hydrogel microspheres for targeted ulcerative colitis therapy. INTERNATIONAL JOURNAL OF PHARMACEUTICS, 639 (122962). [PMID:37068716]

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