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Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) |
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SKU | Size | Availability | Price | Qty |
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O412143-1mg | 1mg | Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding. | $57.90 | |
O412143-5mg | 5mg | Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding. | $119.90 | |
O412143-10mg | 10mg | Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding. | $179.90 | |
O412143-25mg | 25mg | Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding. | $379.90 |
Synonyms | CHEMBL4581355 | CID 118278442 | 3-(cyclopropylmethyl)-6-fluoro-7-methyl-N-[5-(1-methylimidazol-4-yl)pyridin-2-yl]benzimidazol-5-amine |
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Specifications & Purity | Moligand™, ≥98% |
Biochemical and Physiological Mechanisms | ONO-8590580 is a negative allosteric modulator of GABAA α5. |
Storage Temp | Store at -20°C |
Shipped In | Ice chest + Ice pads |
Grade | Moligand™ |
Action Type | ALLOSTERIC MODULATOR |
Mechanism of action | Allosteric modulator of GABA A receptor α5 subunit |
Product Description | Information ONO-8590580 is a negative allosteric modulator of GABAA α5. |
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IUPAC Name | 3-(cyclopropylmethyl)-6-fluoro-7-methyl-N-[5-(1-methylimidazol-4-yl)pyridin-2-yl]benzimidazol-5-amine |
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INCHI | InChI=1S/C21H21FN6/c1-13-20(22)16(7-18-21(13)25-12-28(18)9-14-3-4-14)26-19-6-5-15(8-23-19)17-10-27(2)11-24-17/h5-8,10-12,14H,3-4,9H2,1-2H3,(H,23,26) |
InChi Key | INGJMHPGMVUEKY-UHFFFAOYSA-N |
Canonical SMILES | CC1=C(C(=CC2=C1N=CN2CC3CC3)NC4=NC=C(C=C4)C5=CN(C=N5)C)F |
Isomeric SMILES | CC1=C(C(=CC2=C1N=CN2CC3CC3)NC4=NC=C(C=C4)C5=CN(C=N5)C)F |
PubChem CID | 118278442 |
MeSH Entry Terms | 1-(cyclopropylmethyl)-5-fluoro-4-methyl-N-(5-(1-methyl-1H-imidazol-4-yl)pyridin-2-yl)-1H-benzo(d)imidazol-6-amine;ONO-8590580 |
Molecular Weight | 376.4 |
Enter Lot Number to search for COA:
To view the certificate results,please click on a Lot number.For Lot numbers from past orders,please use our order status section
Lot Number | Certificate Type | Date | Item |
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C2421612 | Certificate of Analysis | Jan 22, 2024 | O412143 |
C2421613 | Certificate of Analysis | Jan 22, 2024 | O412143 |
C2421614 | Certificate of Analysis | Jan 22, 2024 | O412143 |
C2421615 | Certificate of Analysis | Jan 22, 2024 | O412143 |
C2421616 | Certificate of Analysis | Jan 22, 2024 | O412143 |
C2421617 | Certificate of Analysis | Jan 22, 2024 | O412143 |