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ONO-RS-082 - ≥98%, high purity , CAS No.99754-06-0

  • ≥98%
Item Number
O275137
Grouped product items
SKUSizeAvailabilityPrice Qty
O275137-5mg
5mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$68.90
O275137-10mg
10mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$115.90
O275137-25mg
25mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$224.90
O275137-50mg
50mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$406.90
O275137-100mg
100mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$607.90

Potent, reversible phospholipase A 2 (PLA 2 ) inhibitor

Basic Description

SynonymsOno-RS-082|99754-06-0|2-(4-amylcinnamoyl)amino-4-chlorobenzoic acid|2-(p-AMYLCINNAMOYL)AMINO-4-CHLOROBENZOIC ACID|(E)-4-CHLORO-2-(3-(4-PENTYLPHENYL)ACRYLAMIDO)BENZOIC ACID|4-chloro-2-[[(E)-3-(4-pentylphenyl)prop-2-enoyl]amino]benzoic acid|CHEMBL3818672|4-
Specifications & Purity≥98%
Biochemical and Physiological MechanismsPotent, reversible PLA 2 inhibitor (IC 50 = 7 µM). Cell-permeable. Active in ex vivo preparations.
Storage TempProtected from light,Store at -20°C,Desiccated
Shipped InIce chest + Ice pads
NoteWherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour. Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
Product Description

Store at -20°C. It is important to note that this product is reported to be light sensitive. Store In the Dark. Store under desiccating conditions.

Associated Targets

TRPM2 Tchem Transient receptor potential cation channel subfamily M member 2 0 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

KCNK2 Tclin Potassium channel subfamily K member 2 1 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

Names and Identifiers

IUPAC Name 4-chloro-2-[[(E)-3-(4-pentylphenyl)prop-2-enoyl]amino]benzoic acid
INCHI InChI=1S/C21H22ClNO3/c1-2-3-4-5-15-6-8-16(9-7-15)10-13-20(24)23-19-14-17(22)11-12-18(19)21(25)26/h6-14H,2-5H2,1H3,(H,23,24)(H,25,26)/b13-10+
InChi Key MDVFITMPFHDRBZ-JLHYYAGUSA-N
Canonical SMILES CCCCCC1=CC=C(C=C1)C=CC(=O)NC2=C(C=CC(=C2)Cl)C(=O)O
Isomeric SMILES CCCCCC1=CC=C(C=C1)/C=C/C(=O)NC2=C(C=CC(=C2)Cl)C(=O)O
PubChem CID 6438389
Molecular Weight 371.9

Certificates

Certificate of Analysis(COA)

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9 results found

Lot NumberCertificate TypeDateItem
H2426305Certificate of AnalysisMay 14, 2024 O275137
H2426308Certificate of AnalysisMay 14, 2024 O275137
H2426309Certificate of AnalysisMay 14, 2024 O275137
H2426337Certificate of AnalysisMay 14, 2024 O275137
H2426338Certificate of AnalysisMay 14, 2024 O275137
H2426339Certificate of AnalysisMay 14, 2024 O275137
H2426340Certificate of AnalysisMay 14, 2024 O275137
H2426341Certificate of AnalysisMay 14, 2024 O275137
H2426485Certificate of AnalysisMay 14, 2024 O275137

Chemical and Physical Properties

SolubilitySoluble in DMSO to 50 mM (with warming) and in ethanol to 25 mM (with warming)
Sensitivitylight sensitive

Related Documents

Solution Calculators