| SKU | Size | Availability | Price | Qty |
|---|---|---|---|---|
| O654713-1ml | 1ml | Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding. | $385.90 |
| Specifications & Purity | 10mM in DMSO |
|---|---|
| Storage Temp | Store at -80°C |
| Shipped In | Ice chest + Ice pads |
| Product Description | Opiranserin (VVZ-149) hydrochloride, a non-opioid and non-NSAID analgesic candidate, is a dual antagonist of glycine transporter type 2 (GlyT2) and serotonin receptor 2A (5HT2A) , with IC 50 s of 0.86 and 1.3 μM, respectively. Opiranserin hydrochloride shows antagonistic activity on rP2X3 (IC 50 =0.87 μM). Opiranserin hydrochloride is development as an injectable agent for the treatment of postoperative pain IC50& Target:GlyT2 0.86 μM (IC 50 ) P2X3 Receptor rP2X3 0.87 μM (IC 50 ) 5-HT 2A Receptor 1.3 μM (IC 50 ) |
| Canonical SMILES | O=C(C1=CC(OC)=C(OCCCC)C(OC)=C1)NCC2(CCOCC2)N(C)C.[H]Cl |
|---|---|
| Molecular Weight | 430.97 |
Enter Lot Number to search for COA:
