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OTSSP167 - 98%, high purity , CAS No.1431697-89-0, Inhibitor of maternal embryonic leucine zipper kinase

  • Moligand™
  • ≥98%
Item Number
O356679
Grouped product items
SKUSizeAvailabilityPrice Qty
O356679-5mg
5mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$75.90
O356679-25mg
25mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$115.90
O356679-50mg
50mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$282.90
O356679-100mg
100mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$432.90

Basic Description

SynonymsVY778IXU5T | 1431697-89-0 (free base) | AKOS030526527 | 1-(6-(3,5-Dichloro-4-hydroxyphenyl)-4-(((1r,4r)-4-((dimethylamino)methyl)cyclohexyl)amino)-1,5-naphthyridin-3-yl)ethan-1-one | 1-(6-(3,5-Dichloro-4-hydroxyphenyl)-4-((trans-4-((dimethylamino)methyl)c
Specifications & Purity98%
Storage TempStore at -20°C
Shipped InIce chest + Ice pads
GradeMoligand™
Action TypeINHIBITOR
Mechanism of actionInhibitor of maternal embryonic leucine zipper kinase

Associated Targets

MELK Tchem Maternal embryonic leucine zipper kinase 1 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

Names and Identifiers

IUPAC Name 1-[6-(3,5-dichloro-4-hydroxyphenyl)-4-[[4-[(dimethylamino)methyl]cyclohexyl]amino]-1,5-naphthyridin-3-yl]ethanone
INCHI InChI=1S/C25H28Cl2N4O2/c1-14(32)18-12-28-22-9-8-21(16-10-19(26)25(33)20(27)11-16)30-24(22)23(18)29-17-6-4-15(5-7-17)13-31(2)3/h8-12,15,17,33H,4-7,13H2,1-3H3,(H,28,29)
InChi Key DKZYXHCYPUVGAF-UHFFFAOYSA-N
Canonical SMILES CC(=O)C1=CN=C2C=CC(=NC2=C1NC3CCC(CC3)CN(C)C)C4=CC(=C(C(=C4)Cl)O)Cl
Isomeric SMILES CC(=O)C1=CN=C2C=CC(=NC2=C1NC3CCC(CC3)CN(C)C)C4=CC(=C(C(=C4)Cl)O)Cl
PubChem CID 135398499
UN Number 3077
Packing Group III
Molecular Weight 487.42

Certificates

Certificate of Analysis(COA)

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Safety and Hazards(GHS)

Class 9

Related Documents

References

1. Chung S, Suzuki H, Miyamoto T, Takamatsu N, Tatsuguchi A, Ueda K, Kijima K, Nakamura Y, Matsuo Y.  (2012)  Development of an orally-administrative MELK-targeting inhibitor that suppresses the growth of various types of human cancer..  Oncotarget,  (12): (1629-40).  [PMID:23283305]

Solution Calculators