Oxytetracycline - ≥98%, high purity , CAS No.79-57-2

104 Citations
Item Number
O304654
Grouped product items
SKUSizeAvailabilityPrice Qty
O304654-25g
25g
Available within 4-8 weeks(?)
Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience!
$15.90
O304654-100g
100g
Available within 4-8 weeks(?)
Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience!
$48.90
O304654-500g
500g
Available within 4-8 weeks(?)
Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience!
$178.90

Tetracycline antibiotic

Basic Description

SynonymsOxyterracine | Terramycin | Terrafungine | Oxitetracyclin | oxytetracycline | Biostat | Oxitetraciclina | Oxymycin | Oxytetracycline anhydrous | Adamycin | Oxytetracyclinum | Oxytetracycline (anhydrous) | Ryomycin | Geomycin | Oxyterracin | Oxytetracyclin
Specifications & Purity≥98%
Storage TempStore at 2-8°C,Protected from light
Shipped InWet ice
GradeMoligand™
Product Description

Oxytetracycline is an anti-inflammatory, antibiotic, and anti-proliferative agent shown to inhibit mitochondrial protein synthesis. Mechanistic studies show that this compound reduces cytochrome c activity which eventually causes cell growth arrest. Additionally, Oxytetracycline has demonstrated the ability to reduce murine bronchial inflammation. The anti-inflammatory characteristics of this agent are due to its ability to cause a decrease in IL-4, IL-5, IL-13, immune cells, and the ovalbumin-specific IgE. Data suggests that Oxytetracycline is also an inhibitor of NF-κB activation via phosphorylation and degradation of IκB-α.

Names and Identifiers

IUPAC Name (4S,4aR,5S,5aR,6S,12aR)-4-(dimethylamino)-1,5,6,10,11,12a-hexahydroxy-6-methyl-3,12-dioxo-4,4a,5,5a-tetrahydrotetracene-2-carboxamide
INCHI InChI=1S/C22H24N2O9/c1-21(32)7-5-4-6-8(25)9(7)15(26)10-12(21)17(28)13-14(24(2)3)16(27)11(20(23)31)19(30)22(13,33)18(10)29/h4-6,12-14,17,25-26,28,30,32-33H,1-3H3,(H2,23,31)/t12-,13-,14+,17+,21-,22+/m1/s1
InChi Key OWFJMIVZYSDULZ-PXOLEDIWSA-N
Canonical SMILES CC1(C2C(C3C(C(=O)C(=C(C3(C(=O)C2=C(C4=C1C=CC=C4O)O)O)O)C(=O)N)N(C)C)O)O
Isomeric SMILES C[C@@]1([C@H]2[C@@H]([C@H]3[C@@H](C(=O)C(=C([C@]3(C(=O)C2=C(C4=C1C=CC=C4O)O)O)O)C(=O)N)N(C)C)O)O
PubChem CID 54675779
Molecular Weight 460.43

Certificates

Certificate of Analysis(COA)

Enter Lot Number to search for COA:

Find and download the COA for your product by matching the lot number on the packaging.

17 results found

Lot NumberCertificate TypeDateItem
H2416336Certificate of AnalysisAug 03, 2024 O304654
H2416335Certificate of AnalysisAug 03, 2024 O304654
H2416334Certificate of AnalysisAug 03, 2024 O304654
H2416333Certificate of AnalysisAug 03, 2024 O304654
I2306666Certificate of AnalysisAug 09, 2023 O304654
I2306665Certificate of AnalysisAug 09, 2023 O304654
I2306654Certificate of AnalysisAug 09, 2023 O304654
K2216311Certificate of AnalysisNov 23, 2022 O304654
J2218329Certificate of AnalysisOct 20, 2022 O304654
J2218340Certificate of AnalysisOct 20, 2022 O304654
G2328015Certificate of AnalysisDec 21, 2021 O304654
E2305087Certificate of AnalysisDec 21, 2021 O304654
C2303235Certificate of AnalysisDec 21, 2021 O304654
A2214629Certificate of AnalysisDec 21, 2021 O304654
A2214628Certificate of AnalysisDec 21, 2021 O304654
A2214627Certificate of AnalysisDec 21, 2021 O304654
H2231017Certificate of AnalysisJun 17, 2021 O304654

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Chemical and Physical Properties

SolubilitySparingly soluble in aqueous solution at 0.6 mg/mL
SensitivityAir sensitive;Light sensitive;Moisture sensitive
Melt Point(°C)183 °C

Safety and Hazards(GHS)

Pictogram(s) GHS08,   GHS09,   GHS07
Signal Danger
Hazard Statements

H319:Causes serious eye irritation

H302:Harmful if swallowed

H317:May cause an allergic skin reaction

H312:Harmful in contact with skin

H400:Very toxic to aquatic life

H332:Harmful if inhaled

H410:Very toxic to aquatic life with long lasting effects

H360:May damage fertility or the unborn child

H361:Suspected of damaging fertility or the unborn child

H362:May cause harm to breast-fed children

Precautionary Statements

P261:Avoid breathing dust/fume/gas/mist/vapors/spray.

P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses if present and easy to do - continue rinsing.

P273:Avoid release to the environment.

P280:Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352:IF ON SKIN: wash with plenty of water.

P321:Specific treatment (see ... on this label).

P405:Store locked up.

P501:Dispose of contents/container to ...

P264:Wash hands [and …] thoroughly after handling.

P260:Do not breathe dust/fume/gas/mist/vapors/spray.

P271:Use only outdoors or in a well-ventilated area.

P270:Do not eat, drink or smoke when using this product.

P304+P340:IF INHALED: Remove person to fresh air and keep comfortable for breathing.

P272:Contaminated work clothing should not be allowed out of the workplace.

P333+P313:IF SKIN irritation or rash occurs: Get medical advice/attention.

P362+P364:Take off contaminated clothing and wash it before reuse.

P391:Collect spillage.

P330:Rinse mouth.

P263:Avoid contact during pregnancy/while nursing.

P203:Obtain, read and follow all safety instructions before use.

P264+P265:Wash hands [and …] thoroughly after handling. Do not touch eyes.

P301+P317:IF SWALLOWED: Get medical help.

P318:if exposed or concerned, get medical advice.

P317:Get emergency medical help.

P337+P317:If eye irritation persists: Get medical help.

Related Documents

Citations of This Product

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2. Qiang Li, Haochen Li, Xiaofei Zong, Haochao Sun, Yunhao Liu, Ziyi Zhan, Shou Mei, Yanjie Qi, Yangbo Huang, Yuxuan Ye, Fei Pan.  (2024)  Highly efficient adsorption of ciprofloxacin from aqueous solutions by waste cation exchange resin-based activated carbons: Performance, mechanism, and theoretical calculation.  SCIENCE OF THE TOTAL ENVIRONMENT,  912  (169534).  [PMID:38141999]
3. Lin Wang, Fangkun Xiao, Haochen Ge, Yunbo Tong, Congjie Gao, Guiru Zhu.  (2024)  The fabrication of thin-film nanocomposite membrane for organic solvent forward osmosis via host-guest chemistry of α-cyclodextrin.  DESALINATION,  574  (117247).  [PMID:]
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5. Li Wang, Ya Jiao, Kaixin Zhao, Guohao Cheng, Lin Liu, Yongli Liu, Guifen Zhu.  (2024)  A novel carbonized polymer dots-based molecularly imprinted polymer with superior affinity and selectivity for oxytetracycline removal.  JOURNAL OF COLLOID AND INTERFACE SCIENCE,  656  (22): (332).  [PMID:37995403]
6. Song Yan, Cao Chaochao, Shaobo Yang, Jiawei Ji, Zheng Zhou, Yaxin Gu, Chaoze Liu, Rongjuan Zhang, Yanming Xue, Chengchun Tang.  (2024)  Porous boron nitride nanosheets via pyrolysis of melamine phosphate and borate assembly for water purification.  MICROPOROUS AND MESOPOROUS MATERIALS,  366  (112951).  [PMID:]
7. Junru Li, Yunqi Huang, Yanli Zhou, Hui Dong, Haoyuan Wang, Haoran Shan, Yifei Li, Maotian Xu, Xiaobing Wang.  (2023)  Controllable Construction of Two-Dimensional Conductive M3(HHTP)2 Nanorods for Electrochemical Sensing of Malachite Green in Fish.  ACS Applied Nano Materials,  (24): (22916–22926).  [PMID:]
8. Bao Siqi, Yu Xiaotong, Li Xiaolin.  (2023)  Study on the dominant mechanism of direct hole oxidation for the photodegradation of tetracycline.  ENVIRONMENTAL SCIENCE AND POLLUTION RESEARCH,    (1-14).  [PMID:38091223]
9. Peizeng Yang, Jiayue Dong, Haiyan Wang, Teng Zhang, Gregory V. Korshin, Junhe Lu.  (2023)  Formation of N-Nitrosodimethylamine by Sunlight Irradiation of Dimethylamine Compounds in the Presence of Nitrite.  ACS ES&T Water,      [PMID:]
10. Xin-Yu Liu, Xiao-Yun Gu, Chen Liu, Lanre Anthony Gbadegesin, Yang He, Jian-Qiang Zhang.  (2024)  Field migration of veterinary antibiotics via surface runoff from chicken-raising orchard in responding to natural rainfalls.  SCIENCE OF THE TOTAL ENVIRONMENT,  909  (25): (168527).  [PMID:37967624]
11. Qi Pu, Lu Zhang, Nengsheng Ye, Yuhong Xiang.  (2024)  Lanthanide coordination carbon quantum dots construct a ratiometric fluorescent sensor for the detection of norfloxacin in milk.  DYES AND PIGMENTS,  222  (111815).  [PMID:2576652]
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13. Baoliang Dai, Yijing Hu, Yidan Ding, Liguo Shen, Renjie Li, Dieling Zhao, Yang Jiao, Yanchao Xu, Hongjun Lin.  (2024)  Innovative construction of nano-wrinkled polyamide membranes using covalent organic framework nanoflowers for efficient desalination and antibiotic removal.  DESALINATION,  570  (117083).  [PMID:21258371]
14. Xin Xiang, Wenxuan Deng, Zhiyi He, Dongyun Chen, Najun Li, Qingfeng Xu, Hua Li, Jianmei Lu.  (2023)  Graphene aerogel-doped CoFe2O4/MoS2 sheets for magnetic oil absorption and the degradation of contaminants.  Journal of Environmental Chemical Engineering,  11  (111239).  [PMID:10204114]
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16. Fredrick Gudda, Emmanuel Stephen Odinga, Lei Tang, Michael Gatheru Waigi, Jian Wang, Dyaaaldin Abdalmegeed, Yanzheng Gao.  (2023)  Tetracyclines uptake from irrigation water by vegetables: Accumulation and antimicrobial resistance risks.  ENVIRONMENTAL POLLUTION,  338  (122696).  [PMID:37804902]
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18. Shuanghui Jia, Yilan Wu, Hongling Zhou, Hangjun Yan, Yang Liao, Hui Mao.  (2023)  Plant tannin foam anchored iron nanoparticles: Efficient and recyclable degradation of tetracycline antibiotics under high salt conditions.  Journal of Cleaner Production,  426  (4): (139188).  [PMID:30127001]
19. Ligui Wu, Qiaofeng Wu, Jingcheng Xu, Lingling Rong, Xiaoli Yu, Chen Cai, Xiangfeng Huang, Xiaoming Zou.  (2023)  Responses of antibiotic resistance genes in the enhanced biological phosphorus removal system under various antibiotics: Mechanisms and implications.  SCIENCE OF THE TOTAL ENVIRONMENT,  905  (167247).  [PMID:37739079]
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23. Yajun Tian, Xiaohong Wang, Yifan Liang, Benhang Li, Yongze Liu, Li Feng, Jun Li, Liqiu Zhang.  (2023)  Removal of oxytetracycline and sulfamethoxazole in vertical down-up flow constructed wetlands: Efficiency, removal pathways, and occurrence of antibiotic resistance genes.  Journal of Water Process Engineering,  55  (104142).  [PMID:]
24. Tingxia Li, Zhongxiu Chen, Zhongshuai Zhao, Zhongde Liu.  (2023)  A portable test strip fabricated of luminescence lanthanide-functionalized metal-organic frameworks for rapid and visual detection of tetracycline antibiotics.  Analytical Methods,      [PMID:37642116]
25. Bing Wang, RuiQing Zhang, HuiYong Chen, Zhuo Li, EnZhou Liu, HaiXia Ma, Bo Zhou, Hong Hao, LinYu Jiao.  (2023)  Construction of supramolecular S-scheme heterojunctions assisted by hydrogen bond subtle-tuning actuates highly efficient photocatalytic oxidation.  CHEMICAL ENGINEERING JOURNAL,  473  (145290).  [PMID:]
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27. Pengfei Zhu, Xiaolong Wu, Xingyang Xiao, Ming Duan, Dan Luo, Jinru Lin.  (2023)  Construction of Bi12O17Cl2/ZnO-CN Z-scheme photocatalyst with ZIF-8 as precursor to remove antibiotics and Cr(VI) under visible light: Optimization, mechanism and degradation path.  JOURNAL OF ALLOYS AND COMPOUNDS,  966  (171513).  [PMID:]
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32. Yang Zhenhua, Yang Xintong, Zhang Yuexia, Fan Xiaopeng, Cao Yujuan, Li Zhongping, Dong Chuan.  (2023)  Detection of oxytetracycline in milk using a novel carbon dots-based fluorescence probe via facile pyrolysis synthesis.  ENVIRONMENTAL SCIENCE AND POLLUTION RESEARCH,  30  (35): (84002-84010).  [PMID:37353701]
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40. Yujia Yang, Huiyi Shen, Lejin Xu.  (2023)  Three-dimensional graphene anchored nZVI hybrid MnO2 as a dissolved oxygen activated Fenton-like catalyst for efficient mineralization of oxytetracycline.  CHEMICAL ENGINEERING JOURNAL,  464  (142781).  [PMID:]
41. Jiajia Li, Yi Li, Mengzhen Zhu, Qiong Mei, Xi Tang, Yao Wu, Shijun Yue, Yuping Tang, Qizhao Wang.  (2023)  Constructing aloe-emodin/FeOOH organic-inorganic heterojunction for synergetic photocatalysis-Fenton eliminating antibiotic pollutants.  Journal of Environmental Chemical Engineering,  11  (109775).  [PMID:]
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49. Yulin Wang, Libo Nie, Yongbiao Hua, Liang Gong, Xiuzhen Qiu, Huishi Guo.  (2023)  A simple paper-based nickel nanocluster-europium mixed ratio fluorescent probe for rapid visual sensing of tetracyclines.  SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY,  292  (122431).  [PMID:36753865]
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51. Qingyi Zeng, Jing Tan, Beibei Gao, Tao Cai, Qingyan Zhang, Yi-Lin Liu, Sheng Chang, Shuaifei Zhao, Suqing Wu.  (2023)  Embedding Co in perovskite MoO3 for superior catalytic oxidation of refractory organic pollutants with peroxymonosulfate.  CHEMOSPHERE,  314  (137726).  [PMID:36596326]
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53. Lin Li, Sijia Zhang, Yingying Li, Ting Wang, Xiaohong Hou.  (2023)  Hierarchically porous zeolitic imidazole framework-8/cellulose membrane installed in filter as sorbent for microextraction in packed syringe towards trace tetracyclines in water samples.  NEW JOURNAL OF CHEMISTRY,  47  (8): (4068-4073).  [PMID:]
54. Tingting Li, Guoqiang Guo, Haoming Xing, Yiru Wang, Xinyu Luo, Linfan Wang, Chenjie Gu, Yafei Hou, Da Chen.  (2023)  Energy transfer mediated rapid and visual discrimination of tetracyclines and quercetin in food by using N, Cu Co-doped carbon dots.  ANALYTICA CHIMICA ACTA,  1239  (340706).  [PMID:36628714]
55. Fan Yunfeng, Liu Zhimin, Wang Jie, Cui Chen, Hu Leqian.  (2023)  An “off–on” electrochemiluminescence aptasensor for determination of lincomycin based on CdS QDs/carboxylated g-C3N4.  MICROCHIMICA ACTA,  190  (1): (1-9).  [PMID:36477444]
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57. Li Chen, Tahir Maqbool, Ghazanfar Nazir, Congyu Hou, Yanna Xu, Yulong Yang, Xihui Zhang.  (2023)  Peroxymonosulfate activated by composite ceramic membrane for the removal of pharmaceuticals and personal care products (PPCPs) mixture: Insights of catalytic and noncatalytic oxidation.  WATER RESEARCH,  229  (119444).  [PMID:36470049]
58. Li Zhang, Linhong Ge, Lamei Deng, Xinman Tu.  (2022)  Dual Application: p-CuS/n-ZnS Nanocomposite Construction for High-Efficiency Colorimetric Determination and Photocatalytic Degradation of Tetracycline in Water.  Nanomaterials,  12  (23): (4123).  [PMID:36500746]
59. Yiying Yue, Jiamin Gu, Wanli Cheng, Guangping Han, Jingquan Han, Jianchun Jiang.  (2023)  Solid–liquid convertible hydrogel mediated by dual-functional cellulose nanofiber/Eu–dipicolinic acid/carbon dot complexes for high-precision sequential luminescence detection of cupric ion and oxytetracycline.  COMPOSITES SCIENCE AND TECHNOLOGY,  232  (109854).  [PMID:]
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Solution Calculators