Oxytetracycline hydrochloride - BP2007,USP, high purity , CAS No.2058-46-0

Item Number
O110726
Grouped product items
SKUSizeAvailabilityPrice Qty
O110726-100g
100g
In stock
$199.90

Basic Description

SynonymsAKOS015950811 | Forskolin - 20% | Oxytetracycline hydrochloride (JP17/USP) | Toxinal | CCRIS 200 | Intaloxin | Oxamycen | Oxytetracycline.HCl | 2-Naphthacenecarboxamide, 4-(dimethylamino)-1,4,4a,5,5a,6,11,12a-octahydro-3,5,6,10,12,12a-hexahydroxy-6-methyl
Specifications & PurityPharmPure™, USP, BP
Biochemical and Physiological MechanismsOxytetracycline inhibits translation which results in cell death. It binds to the 30S ribosomal subunit and prevents the amino-acyl tRNA from binding to the A site of the ribosome. The binding is reversible in nature. Oxytetracycline is lipophilic so it c
Storage TempStore at 2-8°C
Shipped InWet ice
GradeBP, PharmPure™, USP
Product Description

Oxytetracycline is a tetracycline analog isolated from the actinomycete streptomyces rimosus. Oxytetracycline is an antibiotic indicated for treatment of infections caused by Gram positive and Gram negative microorganisms such as Mycoplasma pneumoniae, Pasteurella pestis, Escherichia coli, Haemophilus influenzae, and Diplococcus pneumoniae. It is used in studies on the oxytetracycline-resistanc?e gene (otrA). Oxytetracycline hydrochloride is used to study phagosome-lysosome (P-L) fusion in P388D1 cells and antibiotic susceptibilities of Mycopasma bovis isolates.

Names and Identifiers

IUPAC Name (4S,4aR,5S,5aR,6S,12aR)-4-(dimethylamino)-1,5,6,10,11,12a-hexahydroxy-6-methyl-3,12-dioxo-4,4a,5,5a-tetrahydrotetracene-2-carboxamide;hydrochloride
INCHI InChI=1S/C22H24N2O9.ClH/c1-21(32)7-5-4-6-8(25)9(7)15(26)10-12(21)17(28)13-14(24(2)3)16(27)11(20(23)31)19(30)22(13,33)18(10)29;/h4-6,12-14,17,25-26,28,30,32-33H,1-3H3,(H2,23,31);1H/t12-,13-,14+,17+,21-,22+;/m1./s1
InChi Key SVDOODSCHVSYEK-IFLJXUKPSA-N
Canonical SMILES CC1(C2C(C3C(C(=O)C(=C(C3(C(=O)C2=C(C4=C1C=CC=C4O)O)O)O)C(=O)N)N(C)C)O)O.Cl
Isomeric SMILES C[C@@]1([C@H]2[C@@H]([C@H]3[C@@H](C(=O)C(=C([C@]3(C(=O)C2=C(C4=C1C=CC=C4O)O)O)O)C(=O)N)N(C)C)O)O.Cl
WGK Germany 2
RTECS QI8225000
PubChem CID 54680782
Molecular Weight 496.89
Beilstein 3853107

Certificates

Certificate of Analysis(COA)

Enter Lot Number to search for COA:

Chemical and Physical Properties

Specific Rotation[α]-172° (C=1,1mol/L HCl)
Melt Point(°C)180°C

Safety and Hazards(GHS)

Pictogram(s) GHS08,   GHS09,   GHS07
Signal Warning
Hazard Statements

H319:Causes serious eye irritation

H410:Very toxic to aquatic life with long lasting effects

H361:Suspected of damaging fertility or the unborn child

H362:May cause harm to breast-fed children

Precautionary Statements

P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses if present and easy to do - continue rinsing.

P273:Avoid release to the environment.

P280:Wear protective gloves/protective clothing/eye protection/face protection.

P405:Store locked up.

P501:Dispose of contents/container to ...

P264:Wash hands [and …] thoroughly after handling.

P260:Do not breathe dust/fume/gas/mist/vapors/spray.

P270:Do not eat, drink or smoke when using this product.

P391:Collect spillage.

P263:Avoid contact during pregnancy/while nursing.

P203:Obtain, read and follow all safety instructions before use.

P264+P265:Wash hands [and …] thoroughly after handling. Do not touch eyes.

P318:if exposed or concerned, get medical advice.

P337+P317:If eye irritation persists: Get medical help.

WGK Germany 2
RTECS QI8225000
Merck Index 6976

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Citations of This Product

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3. Lin He, Jiabin Zhou, Dan Liu, Yajie Wen, Yuxin Gan.  (2024)  Preparation of Fe3O4@GO@MIL-101 nanocomposites and efficient degradation of oxytetracycline hydrochloride by promoting charge separation during the photo-Fenton process.  MATERIALS SCIENCE IN SEMICONDUCTOR PROCESSING,  172  (108050).  [PMID:] [10.1016/j.mssp.2023.108050]
4. Ting Zhu, Jinyang Chen, Shasha Zeng, Jintao Chen, Chunjiao Qi.  (2023)  Highly Stable Fluorescent-Traffic-Light Sensor for Point-of-Care Detection of Tetracycline.  ACS Sensors,  (11): (4272–4280).  [PMID:37862265] [10.1021/acssensors.3c01620]
5. Xiangdong Zhang, Jian Zhang, Bowen Hou, Xueying Yang, Junlian Ren, Chen Shao.  (2024)  Efficient removal of oxytetracycline hydrochloride by ZIF-67 coated hollow spherical CuS (CuS-PVP@ZIF-67) under the synergistic effect of adsorption and PMS activation.  APPLIED SURFACE SCIENCE,  643  (158663).  [PMID:18636086] [10.1016/j.apsusc.2023.158663]
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7. Ciyang Zhang, Keren Lu, Linrui Li, Wu Lei, Mingzhu Xia, Fengyun Wang.  (2024)  A water-stabilized Tb-MOF can be used as a sensitive and selective fluorescence sensor for the detection of oxytetracycline hydrochloride.  SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY,  304  (15): (123379).  [PMID:37729814] [10.1016/j.saa.2023.123379]
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Solution Calculators