Determine the necessary mass, volume, or concentration for preparing a solution.
Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) |
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SKU | Size | Availability | Price | Qty |
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P129988-1mg | 1mg | In stock | $47.90 | |
P129988-5mg | 5mg | In stock | $195.90 | |
P129988-10mg | 10mg | In stock | $325.90 | |
P129988-25mg | 25mg | In stock | $597.90 | |
P129988-50mg | 50mg | In stock | $935.90 | |
P129988-100mg | 100mg | In stock | $1,632.90 |
Synonyms | A903150 | CS-0006648 | D72431 | EX-A2121 | P276 | AS-78319 | DRP53ZDY6H | P-27600;2-(2-chlorophenyl)-5,7-dihydroxy-8-((2R,3S)-2-(hydroxymethyl)-1-methylpyrrolidin-3-yl)-4H-chromen-4-one hydrochloride;P276-00 | 920113-03-7 (HCl) | SCHEMBL663220 | VLB11303 |
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Specifications & Purity | ≥98% |
Storage Temp | Store at -20°C |
Shipped In | Ice chest + Ice pads |
Product Description | P276-00 is a novel CDK1, CDK4 and CDK9 inhibitor with IC50 of 79 nM, 63 nM and 20 nM, respectively. Phase 2/3. |
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Mechanism of Action | Action Type | target ID | Target Name | Target Type | Target Organism | Binding Site Name | References |
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Pubchem Sid | 488200363 |
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Pubchem Sid Url | https://pubchem.ncbi.nlm.nih.gov/substance/488200363 |
IUPAC Name | 2-(2-chlorophenyl)-5,7-dihydroxy-8-[(2R,3S)-2-(hydroxymethyl)-1-methylpyrrolidin-3-yl]chromen-4-one;hydrochloride |
INCHI | InChI=1S/C21H20ClNO5.ClH/c1-23-7-6-12(14(23)10-24)19-15(25)8-16(26)20-17(27)9-18(28-21(19)20)11-4-2-3-5-13(11)22;/h2-5,8-9,12,14,24-26H,6-7,10H2,1H3;1H/t12-,14+;/m1./s1 |
InChi Key | OOVTUOCTLAERQD-OJMBIDBESA-N |
Canonical SMILES | CN1CCC(C1CO)C2=C(C=C(C3=C2OC(=CC3=O)C4=CC=CC=C4Cl)O)O.Cl |
Isomeric SMILES | CN1CC[C@H]([C@@H]1CO)C2=C(C=C(C3=C2OC(=CC3=O)C4=CC=CC=C4Cl)O)O.Cl |
PubChem CID | 23643975 |
Molecular Weight | 438.3 |
Enter Lot Number to search for COA:
Find and download the COA for your product by matching the lot number on the packaging.
Lot Number | Certificate Type | Date | Item |
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Certificate of Analysis | Dec 10, 2024 | P129988 | |
Certificate of Analysis | Dec 10, 2024 | P129988 | |
Certificate of Analysis | Dec 10, 2024 | P129988 | |
Certificate of Analysis | Dec 08, 2022 | P129988 | |
Certificate of Analysis | Dec 08, 2022 | P129988 | |
Certificate of Analysis | Dec 08, 2022 | P129988 | |
Certificate of Analysis | Dec 08, 2022 | P129988 | |
Certificate of Analysis | Dec 08, 2022 | P129988 | |
Certificate of Analysis | Dec 08, 2022 | P129988 | |
Certificate of Analysis | Dec 08, 2022 | P129988 | |
Certificate of Analysis | Dec 08, 2022 | P129988 | |
Certificate of Analysis | Dec 08, 2022 | P129988 |
Solubility | DMSO: 88 mg/mL;Water:88 mg/mL;Ethanol:7 mg/mL |
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Sensitivity | Moisture sensitive |
Starting at $1,087.90