p32 inhibitor M36 (M36) is a p32 mitochondrial protein inhibitor, which binds directly to p32 and inhibits p32 association with LyP-1
In Vitro
p32 Inhibitor M36 inhibits SF188 glioma cells proliferation (IC 50 of 77.9 μM in complete media) and is much more potent under low glucose conditions with an IC 50 of 7.3 μM. p32 Inhibitor M36 is selective for p32 overexpressing cells. p32 Inhibitor M36 is also a potent inhibitor of patient-derived neurospheres with an IC 50 of 2.8 μM. MCE has not independently confirmed the accuracy of these methods. They are for reference only.