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Paroxetine - 97%, high purity , Serotonin transporter inhibitor, CAS No.61869-08-7, Serotonin transporter inhibitor

  • Moligand™
  • ≥97%
Item Number
P304169
Grouped product items
SKUSizeAvailabilityPrice Qty
P304169-250mg
250mg
In stock
$241.90
P304169-1g
1g
In stock
$756.90
View related series
P2X4 Antagonist SERT Inhibitor

Basic Description

Synonymsparoxetine|61869-08-7|Paxil|Frosinor|Casbol|Motivan|PaxPar|Paxil CR|Paxetil|Paroxetina|Paroxetinum|Seroxat|Aropax|Paroxetinum [INN-Latin]|Paroxetina [INN-Spanish]|BRL 29060|Arketis|Besitram|Daparox|Oxetine|Parogen|Xetanor|Arotin|BRL-29060|(-)-Paroxetine|F
Specifications & Purity97%
Storage TempStore at 2-8°C,Protected from light,Argon charged
Shipped InWet ice
GradeMoligand™
Action TypeANTAGONIST, INHIBITOR
Mechanism of actionSerotonin transporter inhibitor

Associated Targets

CYP2D6 Tclin Cytochrome P450 2D6 1 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

SLC6A2 Tclin Sodium-dependent noradrenaline transporter 5 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

SLC6A3 Tclin Sodium-dependent dopamine transporter 4 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

SLC6A4 Tclin Sodium-dependent serotonin transporter 18 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

MPO Tchem Myeloperoxidase 1 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

CHRM5 Tclin Muscarinic acetylcholine receptor M5 1 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

CHRM3 Tclin Muscarinic acetylcholine receptor M3 1 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

CHRM4 Tclin Muscarinic acetylcholine receptor M4 1 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

CHRM1 Tclin Muscarinic acetylcholine receptor M1 1 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

KCNH2 Tclin Potassium voltage-gated channel subfamily H member 2 1 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

P2RX4 Tchem P2X purinoceptor 4 3 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

Names and Identifiers

Pubchem Sid488183349
Pubchem Sid Urlhttps://pubchem.ncbi.nlm.nih.gov/substance/488183349
IUPAC Name (3S,4R)-3-(1,3-benzodioxol-5-yloxymethyl)-4-(4-fluorophenyl)piperidine
INCHI InChI=1S/C19H20FNO3/c20-15-3-1-13(2-4-15)17-7-8-21-10-14(17)11-22-16-5-6-18-19(9-16)24-12-23-18/h1-6,9,14,17,21H,7-8,10-12H2/t14-,17-/m0/s1
InChi Key AHOUBRCZNHFOSL-YOEHRIQHSA-N
Canonical SMILES C1CNCC(C1C2=CC=C(C=C2)F)COC3=CC4=C(C=C3)OCO4
Isomeric SMILES C1CNC[C@H]([C@@H]1C2=CC=C(C=C2)F)COC3=CC4=C(C=C3)OCO4
PubChem CID 43815
Molecular Weight 329.37

Certificates

Certificate of Analysis(COA)

Enter Lot Number to search for COA:

To view the certificate results,please click on a Lot number.For Lot numbers from past orders,please use our order status section

4 results found

Lot NumberCertificate TypeDateItem
D2320845Certificate of AnalysisApr 10, 2023 P304169
D2320847Certificate of AnalysisApr 10, 2023 P304169
D2320854Certificate of AnalysisApr 10, 2023 P304169
D2320863Certificate of AnalysisApr 10, 2023 P304169

Chemical and Physical Properties

Sensitivitylight sensitive
Flash Point(°C)227.0±28.7℃
Boil Point(°C)451.7±45.0 ℃ at 760 mmHg

Safety and Hazards(GHS)

Pictogram(s) GHS08,   GHS09,   GHS07
Signal Danger
Hazard Statements

H302:Harmful if swallowed

H400:Very toxic to aquatic life

H410:Very toxic to aquatic life with long lasting effects

H360:May damage fertility or the unborn child

H361:Suspected of damaging fertility or the unborn child

Precautionary Statements

P273:Avoid release to the environment.

P280:Wear protective gloves/protective clothing/eye protection/face protection.

P405:Store locked up.

P501:Dispose of contents/container to ...

P264:Wash hands [and …] thoroughly after handling.

P270:Do not eat, drink or smoke when using this product.

P391:Collect spillage.

P330:Rinse mouth.

P203:Obtain, read and follow all safety instructions before use.

P301+P317:IF SWALLOWED: Get medical help.

P318:if exposed or concerned, get medical advice.

Related Documents

References

1. Coleman JA, Green EM, Gouaux E.  (2016)  X-ray structures and mechanism of the human serotonin transporter..  Nature,  532  (7599): (334-9).  [PMID:27049939]

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