Patisiran sodium - 96%, high purity , CAS No.1386913-72-9

Item Number

P646702

• Specifications & Purity: ≥96%
• Biochemical and Physiological Mechanisms: 帕替西兰钠是一种双链小干扰 RNA，靶向转甲状腺素（TTR）信使 RNA 中的一个序列。帕替西兰钠能特异性抑制突变型和野生型 TTR 的肝脏合成。帕替西兰钠可用于
• Storage Temp: Store at -20°C,Argon charged
• Shipped In: Ice chest + Ice pads

Product Description

Patisiran sodium is a double-stranded small interfering RNA that targets a sequence within the transthyretin (TTR) messenger RNA. Patisiran sodium specifically inhibits hepatic synthesis of mutant and wild-type TTR. Patisiran sodium can be used for the research of hereditary TTR amyloidosis .

In Vitro

Patisiran sodium causes TTR degradation (via RNA interference) and subsequently a reduction in serum TTR protein levels and tissue TTR protein deposits by specifically binding to a genetically conserved sequence in the 3' untranslated region of mutant and wild-type transthyretin (TTR) messenger RNA. MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Form:Solid