| SKU | Size | Availability | Price | Qty |
|---|---|---|---|---|
| P654665-1ml | 1ml | Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding. | $465.90 |
| Specifications & Purity | 10mM in DMSO |
|---|---|
| Biochemical and Physiological Mechanisms | PD-1-IN-24 (compound 1) is an orally active PD-1 inhibitor. |
| Storage Temp | Protected from light,Desiccated,Store at -80°C |
| Shipped In | Ice chest + Ice pads |
| Product Description | PD-1-IN-24 (compound 1) is an orally active PD-1 inhibitor. In Vivo PD-1-IN-24 (compound 1, 15mg/kg, PO, BID) exhibits TGI(%) of 19.96% in the subcutaneous 4T1 murine breast cancer model in BALB/c mice . PD-1-IN-24 (compound 1, 15mg/kg, PO, BID) dose-dependently inhibits tumor growth in the Bl6F10 models with TGI% of 35.59% (30 mg/kg), 38.87% (60 mg/kg) and 47.35% (120 mg/kg), respectively . MCE has not independently confirmed the accuracy of these methods. They are for reference only. |
| Canonical SMILES | CC1=C(C2=CC=CC=C2)C=CC=C1/C=C/C3=C(C=CC(CN[C@](CO)(C)C(O)=O)=C3)C(F)(F)F |
|---|---|
| Molecular Weight | 469.50 |
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