Click Here for 5% Off Your First Aladdin Purchase!

PD 174265 - ≥98%, high purity , CAS No.216163-53-0, Inhibitor of epidermal growth factor receptor

  • Moligand™
  • ≥98%
Item Number
P276170
Grouped product items
SKUSizeAvailabilityPrice Qty
P276170-1mg
1mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$118.90

Potent, selective, reversible EGFR tyrosine kinase inhibitor

Basic Description

SynonymsN-[4-[(3-Bromophenyl)amino]-6-quinazolinyl]propanamide
Specifications & PurityMoligand™, ≥98%
Biochemical and Physiological MechanismsPotent, selective, reversible EGFR tyrosine kinase inhibitor (IC 50 = 0.45 nM). Antitumor agent. Cell permeable. Active in vivo and in vitro .s
SourceSynthetic
Storage TempStore at -20°C,Desiccated
Shipped InIce chest + Ice pads
GradeMoligand™
Action TypeINHIBITOR
Mechanism of actionInhibitor of epidermal growth factor receptor
NoteWherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour. Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
Product Description

Store at -20°C. Store under desiccating conditions. The product can be stored for up to 12 months.

Names and Identifiers

IUPAC Name N-[4-(3-bromoanilino)quinazolin-6-yl]propanamide
INCHI InChI=1S/C17H15BrN4O/c1-2-16(23)21-13-6-7-15-14(9-13)17(20-10-19-15)22-12-5-3-4-11(18)8-12/h3-10H,2H2,1H3,(H,21,23)(H,19,20,22)
InChi Key WUPUZEMRHDROEO-UHFFFAOYSA-N
Canonical SMILES CCC(=O)NC1=CC2=C(C=C1)N=CN=C2NC3=CC(=CC=C3)Br
Isomeric SMILES CCC(=O)NC1=CC2=C(C=C1)N=CN=C2NC3=CC(=CC=C3)Br
PubChem CID 4709
Molecular Weight 371.23

Certificates

Certificate of Analysis(COA)

Enter Lot Number to search for COA:

Chemical and Physical Properties

SolubilitySoluble in DMSO to 100 mM

Related Documents

Solution Calculators