FALLOTEIN | PDGFC | PDGF-C | platelet derived growth factor C | platelet-derived growth factor C | SCDGFSpinal cord-derived growth factor | secretory growth factor-like protein | VEGF-E | Fallotein antibody | hSCDGF antibody | PDGF-C antibody | PDGFC anti
Specifications & Purity
ExactAb™, Validated, Carrier Free, 1.0 mg/mL
Host species
Rabbit
Specificity
PDGFC
Immunogen
KLH-conjugated synthetic peptide encompassing a sequence within the center region of human PDGFC.
Positive Control
WB: A549 and HEL cell lysates. IHC: Human colon cancer tissue.
Conjugation
Unconjugated
Grade
Carrier Free, ExactAb™, Validated
Product Description
Rabbit anti Human PDGFC Antibody, Polyclonal, could be used for WB, IHC and so on. Application WB: 1/500-1/1000 IHC: 1/50 - 1/100 Protein Function Potent mitogen and chemoattractant for cells of mesenchymal origin. Binding of this growth factor to its affinity receptor elicits a variety of cellular responses. Appears to be involved in the three stages of wound healing: inflammation, proliferation and remodeling. Involved in fibrotic processes, in which transformation of interstitial fibroblasts into myofibroblasts plus collagen deposition occurs. Acts as a specific ligand for alpha platelet-derived growth factor receptor homodimer, and alpha and beta heterodimer. Binding to receptors induces their activation by tyrosine phosphorylation. The CUB domain has mitogenic activity in coronary artery smooth muscle cells, suggesting a role beyond the maintainance of the latency of the PDGF domain. In the nucleus, PDGFC seems to have additional function. Seems to be involved in palatogenesis.
Product Properties
Isotype
Rabbit IgG
SDS-PAGE
150 kDa
Purification Method
Immunogen affinity purified
Form
Liquid
Concentration
1.0 mg/mL
Storage Temp
Store at -20°C,Avoid repeated freezing and thawing
Shipped In
Ice chest + Ice pads
Stability And Storage
Store at 4℃ short term (1-2 weeks). Store at -20℃ long term (12 months). Upon delivery aliquot. Avoid freeze/thaw cycle.
Images
PDGFC Antibody (Ab120901) - Western Blot All lanes: PDGFC Antibody (Ab120901) at 1/1000 dilution Samples: Lysates at 20 µg per lane Secondary: Goat Anti-Rabbit IgG H&L (HRP) (Ab176443) at 1/20000 dilution Predicted band size: 39 kDa Observed band size: 18 kDa Exposure time: 20.0 s
PDGFC Antibody (Ab120901) - IHC Immunohistochemical analysis of PDGFC staining in human colon cancer formalin fixed paraffin embedded tissue section. The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH 6.0). The section was then incubated with PDGFC Antibody (Ab120901) at room temperature and detected using an HRP conjugated compact polymer system.
Associated Targets(Human)
PDGFCTbioPlatelet-derived growth factor C (0 Activities)