PDGFC Antibody

    Application:
  • IHC
  • WB
Features and benefits
  • Host species: Rabbit
  • Species reactivity(Reacts with): Human,Mouse
  • Isotype: Rabbit IgG
  • Conjugation: Unconjugated
Item Number
Ab120901
Grouped product items
SKUSizeAvailabilityPrice Qty
Ab120901-10μl
10μl
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$69.90
Ab120901-50μl
50μl
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$199.90
Ab120901-100μl
100μl
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$269.90
Ab120901-1ml
1ml
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$2,499.90

pAb; Rabbit anti Human PDGFC Antibody; WB, IHC; Unconjugated

Basic Description

Product NamePDGFC Antibody
SynonymsFALLOTEIN | PDGFC | PDGF-C | platelet derived growth factor C | platelet-derived growth factor C | SCDGFSpinal cord-derived growth factor | secretory growth factor-like protein | VEGF-E | Fallotein antibody | hSCDGF antibody | PDGF-C antibody | PDGFC anti
Specifications & PurityExactAb™, Validated, Carrier Free, 1.0 mg/mL
Host speciesRabbit
SpecificityPDGFC
ImmunogenKLH-conjugated synthetic peptide encompassing a sequence within the center region of human PDGFC.
Positive ControlWB: A549 and HEL cell lysates. IHC: Human colon cancer tissue.
ConjugationUnconjugated
GradeCarrier Free, ExactAb™, Validated
Product Description

Rabbit anti Human PDGFC Antibody, Polyclonal, could be used for WB, IHC and so on.
Application
WB: 1/500-1/1000
IHC: 1/50 - 1/100
Protein Function
Potent mitogen and chemoattractant for cells of mesenchymal origin. Binding of this growth factor to its affinity receptor elicits a variety of cellular responses. Appears to be involved in the three stages of wound healing: inflammation, proliferation and remodeling. Involved in fibrotic processes, in which transformation of interstitial fibroblasts into myofibroblasts plus collagen deposition occurs. Acts as a specific ligand for alpha platelet-derived growth factor receptor homodimer, and alpha and beta heterodimer. Binding to receptors induces their activation by tyrosine phosphorylation. The CUB domain has mitogenic activity in coronary artery smooth muscle cells, suggesting a role beyond the maintainance of the latency of the PDGF domain. In the nucleus, PDGFC seems to have additional function. Seems to be involved in palatogenesis.

Product Properties

IsotypeRabbit IgG
SDS-PAGE150 kDa
Purification MethodImmunogen affinity purified
FormLiquid
Concentration1.0 mg/mL
Storage TempStore at -20°C,Avoid repeated freezing and thawing
Shipped InIce chest + Ice pads
Stability And StorageStore at 4℃ short term (1-2 weeks). Store at -20℃ long term (12 months). Upon delivery aliquot. Avoid freeze/thaw cycle.

Images

PDGFC Antibody (Ab120901) - Western Blot
All lanes: PDGFC Antibody (Ab120901) at 1/1000 dilution
Samples: Lysates at 20 µg per lane
Secondary: Goat Anti-Rabbit IgG H&L (HRP) (Ab176443) at 1/20000 dilution
Predicted band size: 39 kDa
Observed band size: 18 kDa
Exposure time: 20.0 s

PDGFC Antibody (Ab120901) - IHC
Immunohistochemical analysis of PDGFC staining in human colon cancer formalin fixed paraffin embedded tissue section. The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH 6.0). The section was then incubated with PDGFC Antibody (Ab120901) at room temperature and detected using an HRP conjugated compact polymer system.

Associated Targets(Human)

PDGFC Tbio Platelet-derived growth factor C (0 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

Application

ApplicationDilution info
WB 1/500-1/1000

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1/500-1/1000

IHC

1/50-1/100

Certificates

Certificate of Analysis(COA)

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Related Documents

Solution Calculators